Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission

Glycosylation Is Dispensable for Sorting of Synaptotagmin 1 but Is Critical for Targeting of SV2 and Synaptophysin to Recycling Synaptic Vesicles

(2012) Sung E. Kwon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screen

(2012) Camin Dean et al.   MOLECULAR BIOLOGY OF THE CELL

Doc2 Is a Ca2+ Sensor Required for Asynchronous Neurotransmitter Release

(2011) Jun Yao et al.   CELL

Receptor Binding Enables Botulinum Neurotoxin B to Sense Low pH for Translocation Channel Assembly

(2011) Shihu Sun et al.   Cell Host & Microbe

Spontaneous Glutamate Release Is Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor

(2011) N. P. Vyleta et al.   JOURNAL OF NEUROSCIENCE

Membrane Penetration by Synaptotagmin Is Required for Coupling Calcium Binding to Vesicle Fusion In Vivo

(2011) B. E. Paddock et al.   JOURNAL OF NEUROSCIENCE

Mechanism and function of synaptotagmin-mediated membrane apposition

(2011) Enfu Hui et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synaptotagmin Increases the Dynamic Range of Synapses by Driving Ca2+-Evoked Release and by Clamping a Near-Linear Remaining Ca2+ Sensor

(2011) Olexiy Kochubey et al.   NEURON

Spontaneous Neurotransmission: An Independent Pathway for Neuronal Signaling?

(2011) Ege T. Kavalali et al.   PHYSIOLOGY

Regulation of Exocytosis and Fusion Pores by Synaptotagmin-Effector Interactions

(2010) Zhen Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

Single-molecule FRET–derived model of the synaptotagmin 1–SNARE fusion complex

(2010) Ucheor B Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Doc2b Is a High-Affinity Ca2+ Sensor for Spontaneous Neurotransmitter Release

(2010) A. J. Groffen et al.   SCIENCE

Synaptotagmin-Mediated Bending of the Target Membrane Is a Critical Step in Ca2+-Regulated Fusion

(2009) Enfu Hui et al.   CELL

Autapses and Networks of Hippocampal Neurons Exhibit Distinct Synaptic Transmission Phenotypes in the Absence of Synaptotagmin I

(2009) H. Liu et al.   JOURNAL OF NEUROSCIENCE

Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release

(2009) Jun Xu et al.   NATURE NEUROSCIENCE

Tilting the Balance between Facilitatory and Inhibitory Functions of Mammalian and Drosophila Complexins Orchestrates Synaptic Vesicle Exocytosis

(2009) Mingshan Xue et al.   NEURON

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

How Does Synaptotagmin Trigger Neurotransmitter Release?

(2008) Edwin R. Chapman   Annual Review of Biochemistry

Conformation and Membrane Position of the Region Linking the Two C2 Domains in Synaptotagmin 1 by Site-Directed Spin Labeling†

(2008) Hao Huang et al.   BIOCHEMISTRY

Analysis of the Synaptotagmin Family during Reconstituted Membrane Fusion

(2008) Akhil Bhalla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptotagmin C2B Domain Regulates Ca2+-triggered Fusionin Vitro

(2008) Jon D. Gaffaney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+

(2008) Michael C Chicka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY