Quantitative analysis of peptides and proteins in biomedicine by targeted mass spectrometry

Comparison of standard- and nano-flow liquid chromatography platforms for MRM-based quantitation of putative plasma biomarker proteins

(2012) Andrew J. Percy et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Multiplex Targeted Proteomic Assay for Biomarker Detection in Plasma: A Pancreatic Cancer Biomarker Case Study

(2012) Sheng Pan et al.   JOURNAL OF PROTEOME RESEARCH

Mass Spectrometry: Reconnaissance at the Frontiers of Biology

(2012) Alma L. Burlingame et al.   MOLECULAR & CELLULAR PROTEOMICS

Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions

(2012) Paola Picotti et al.   NATURE METHODS

Antibody-free, targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasma/serum

(2012) T. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MRM-based multiplexed quantitation of 67 putative cardiovascular disease biomarkers in human plasma

(2012) Dominik Domanski et al.   PROTEOMICS

Reproducible Quantification of Cancer-Associated Proteins in Body Fluids Using Targeted Proteomics

(2012) R. Huttenhain et al.   Science Translational Medicine

Mass Spectrometry in Biomarker Applications: From Untargeted Discovery to Targeted Verification, and Implications for Platform Convergence and Clinical Application

(2011) R. D. Smith   CLINICAL CHEMISTRY

A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease

(2011) Terri A Addona et al.   NATURE BIOTECHNOLOGY

A targeted proteomics–based pipeline for verification of biomarkers in plasma

(2011) Jeffrey R Whiteaker et al.   NATURE BIOTECHNOLOGY

mProphet: automated data processing and statistical validation for large-scale SRM experiments

(2011) Lukas Reiter et al.   NATURE METHODS

Mutant proteins as cancer-specific biomarkers

(2011) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A database of reaction monitoring mass spectrometry assays for elucidating therapeutic response in cancer

(2011) Elizabeth R. Remily-Wood et al.   Proteomics Clinical Applications

Immunoassays in microfluidic systems

(2010) Alphonsus H. C. Ng et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Online High-Flow Peptide Immunoaffinity Enrichment and Nanoflow LC-MS/MS: Assay Development for Total Salivary Pepsin/Pepsinogen

(2010) H. Neubert et al.   CLINICAL CHEMISTRY

High-content affinity-based proteomics: unlocking protein biomarker discovery

(2010) Edward N Brody et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

The Bottleneck in the Cancer Biomarker Pipeline and Protein Quantification through Mass Spectrometry-Based Approaches: Current Strategies for Candidate Verification

(2009) S. Makawita et al.   CLINICAL CHEMISTRY

Automated Detection of Inaccurate and Imprecise Transitions in Peptide Quantification by Multiple Reaction Monitoring Mass Spectrometry

(2009) S. E. Abbatiello et al.   CLINICAL CHEMISTRY

The Clinical Plasma Proteome: A Survey of Clinical Assays for Proteins in Plasma and Serum

(2009) N. L. Anderson   CLINICAL CHEMISTRY

Antibody-Based Protein Multiplex Platforms: Technical and Operational Challenges

(2009) A. A. Ellington et al.   CLINICAL CHEMISTRY

Isotope dilution strategies for absolute quantitative proteomics

(2009) Virginie Brun et al.   Journal of Proteomics

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

(2009) Terri A Addona et al.   NATURE BIOTECHNOLOGY

Immuno-MALDI-TOF MS: New perspectives for clinical applications of mass spectrometry

(2009) Katrin Sparbier et al.   PROTEOMICS

Quantification of NTproBNP in Rat Serum Using Immunoprecipitation and LC/MS/MS:  a Biomarker of Drug-Induced Cardiac Hypertrophy

(2008) Michael Berna et al.   ANALYTICAL CHEMISTRY

Quantification of Thyroglobulin, a Low-Abundance Serum Protein, by Immunoaffinity Peptide Enrichment and Tandem Mass Spectrometry

(2008) A. N. Hoofnagle et al.   CLINICAL CHEMISTRY

Clinical Quantitation of Prostate-specific Antigen Biomarker in the Low Nanogram/Milliliter Range by Conventional Bore Liquid Chromatography-Tandem Mass Spectrometry (Multiple Reaction Monitoring) Coupling and Correlation with ELISA Tests

(2008) Tanguy Fortin et al.   MOLECULAR & CELLULAR PROTEOMICS

Accurate Inclusion Mass Screening

(2008) Jacob D. Jaffe et al.   MOLECULAR & CELLULAR PROTEOMICS