Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

Clinical picture and treatment of 2212 patients with common variable immunodeficiency

(2014) Benjamin Gathmann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CTLA-4 Controls Regulatory T Cell Peripheral Homeostasis and Is Required for Suppression of Pancreatic Islet Autoimmunity

(2014) E. M. Schmidt et al.   JOURNAL OF IMMUNOLOGY

Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4

(2014) H. S. Kuehn et al.   SCIENCE

Germline Mutations in NFKB2 Implicate the Noncanonical NF-κB Pathway in the Pathogenesis of Common Variable Immunodeficiency

(2013) Karin Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Long-term safety of abatacept in patients with rheumatoid arthritis

(2013) Fabiola Atzeni et al.   AUTOIMMUNITY REVIEWS

Human regulatory T cells are selectively activated by low-dose application of the CD28 superagonist TGN1412/TAB08

(2013) Paula Tabares et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Treg and CTLA-4: Two intertwining pathways to immune tolerance

(2013) Lucy S.K. Walker   JOURNAL OF AUTOIMMUNITY

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

(2013) Carrie L Lucas et al.   NATURE IMMUNOLOGY

Genetic insights into common pathways and complex relationships among immune-mediated diseases

(2013) Miles Parkes et al.   NATURE REVIEWS GENETICS

Phosphoinositide 3-Kinase   Gene Mutation Predisposes to Respiratory Infection and Airway Damage

(2013) I. Angulo et al.   SCIENCE

Immunodeficiency with Autoimmunity: Beyond the Paradox

(2013) R. Bacchetta et al.   Frontiers in Immunology

Abatacept for lupus nephritis: Alternative definitions of complete response support conflicting conclusions

(2012) David Wofsy et al.   ARTHRITIS AND RHEUMATISM

The many faces of the clinical picture of common variable immune deficiency

(2012) Elena S. Resnick et al.   Current Opinion in Allergy and Clinical Immunology

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Severe Developmental B Lymphopoietic Defects in Foxp3-Deficient Mice are Refractory to Adoptive Regulatory T Cell Therapy

(2012) Julia Riewaldt et al.   Frontiers in Immunology

Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome: A Paradigm of Immunodeficiency with Autoimmunity

(2012) Federica Barzaghi et al.   Frontiers in Immunology

The variant call format and VCFtools

(2011) P. Danecek et al.   BIOINFORMATICS

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation

(2011) Kajsa Wing et al.   TRENDS IN IMMUNOLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

An Enigmatic Tail of CD28 Signaling

(2010) J. S. Boomer et al.   Cold Spring Harbor Perspectives in Biology

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells

(2009) Hélène Bour-Jordan et al.   IMMUNOLOGICAL REVIEWS

CD4+regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

(2009) Randall H. Friedline et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE