Astrocyte-derived lactosylceramide implicated in multiple sclerosis

Inhibition of Glycosphingolipid Synthesis Ameliorates Atherosclerosis and Arterial Stiffness in Apolipoprotein E −/− Mice and Rabbits Fed a High-Fat and -Cholesterol Diet

(2014) Subroto Chatterjee et al.   CIRCULATION

Astrocyte CCL2 sustains immune cell infiltration in chronic experimental autoimmune encephalomyelitis

(2014) Roy Y. Kim et al.   JOURNAL OF NEUROIMMUNOLOGY

Multiple Sclerosis: Current and Emerging Disease-Modifying Therapies and Treatment Strategies

(2014) Dean M. Wingerchuk et al.   MAYO CLINIC PROCEEDINGS

Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation

(2014) Lior Mayo et al.   NATURE MEDICINE

 4GalT6 is involved in the synthesis of lactosylceramide with less intensity than  4GalT5

(2013) N. Tokuda et al.   GLYCOBIOLOGY

Modeling the heterogeneity of multiple sclerosis in animals

(2013) Sarah B. Simmons et al.   TRENDS IN IMMUNOLOGY

Impairment of hippocampal long-term potentiation and failure of learning in mice treated with d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol

(2012) Hiroki Fujiwara et al.   BIOMEDICAL RESEARCH-TOKYO

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

Inhibition of ganglioside synthesis reduces the neuronal survival activity of astrocytes

(2010) Yuko Akasako et al.   NEUROSCIENCE LETTERS

Early lethality of β-1,4-galactosyltransferase V-mutant mice by growth retardation

(2008) Tadahiro Kumagai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Astrocytes in multiple sclerosis: A product of their environment

(2008) A. Nair et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regulation of Lactosylceramide Synthase (Glucosylceramide β1→4 Galactosyltransferase); Implication as A Drug Target

(2008) Subroto Chatterjee et al.   CURRENT DRUG TARGETS

The Yin and Yang of lactosylceramide metabolism: Implications in cell function

(2007) Subroto Chatterjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS