Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta

Evaluation of teriparatide treatment in adults with osteogenesis imperfecta

(2014) Eric S. Orwoll et al.   JOURNAL OF CLINICAL INVESTIGATION

Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma

(2014) John C. Morris et al.   PLoS One

Differential Effects of Collagen Prolyl 3-Hydroxylation on Skeletal Tissues

(2014) Erica P. Homan et al.   PLoS Genetics

E-selectin ligand 1 regulates bone remodeling by limiting bioactive TGF-  in the bone microenvironment

(2013) T. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms

(2012) Frank Thiele et al.   HUMAN MOLECULAR GENETICS

The Biology of Small Leucine-rich Proteoglycans in Bone Pathophysiology

(2012) Dragana Nikitovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

(2012) Lingling Xian et al.   NATURE MEDICINE

Antibody Targeting of TGF-β in Cancer Patients

(2011) Scott Lonning et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis

(2011) Howard Trachtman et al.   KIDNEY INTERNATIONAL

Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo

(2010) James R Edwards et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Generalized Connective Tissue Disease in Crtap-/- Mouse

(2010) Dustin Baldridge et al.   PLoS One

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

(2010) Z.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variable bone fragility associated with an Amish COL1A2 variant and a knock-in mouse model

(2009) Ethan Daley et al.   JOURNAL OF BONE AND MINERAL RESEARCH

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

Effect of the -Gly-3(S)-hydroxyprolyl-4(R)-hydroxyprolyl- tripeptide unit on the stability of collagen model peptides

(2008) Kazunori Mizuno et al.   FEBS Journal

CRTAPandLEPRE1mutations in recessive osteogenesis imperfecta

(2008) Dustin Baldridge et al.   HUMAN MUTATION