Journal
NATURE MEDICINE
Volume 18, Issue 4, Pages 491-492Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nm.2718
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Funding
- NCRR NIH HHS [M01 RR000056] Funding Source: Medline
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Vitamin E is commonly taken as a dietary supplement because it has been shown to have cardioprotective effects. However, its effects on bone metabolism are unknown. A new study in mice shows that alpha-tocopherol, the main isoform of vitamin E, stimulates bone osteoclast fusion independently of its antioxidant activity, resulting in increased bone resorption (pages 589-594).
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