The RIP1-RIP3 complex initiates mitochondrial fission to fuel NLRP3

Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization and K+Efflux

(2014) Luigi Franchi et al.   JOURNAL OF IMMUNOLOGY

RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway

(2014) Xiaqiong Wang et al.   NATURE IMMUNOLOGY

The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation

(2013) Naeha Subramanian et al.   CELL

The DHX33 RNA Helicase Senses Cytosolic RNA and Activates the NLRP3 Inflammasome

(2013) Hiroki Mitoma et al.   IMMUNITY

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

The NLRP3 Inflammasome Detects Encephalomyocarditis Virus and Vesicular Stomatitis Virus Infection

(2011) J. V. Rajan et al.   JOURNAL OF VIROLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Mitochondrial fragmentation in neurodegeneration

(2008) Andrew B. Knott et al.   NATURE REVIEWS NEUROSCIENCE