Article
Medicine, General & Internal
Samuel Knoedler, Leonard Knoedler, Helena Baecher, Martin Kauke-Navarro, Doha Obed, Cosima C. Hoch, Yannick F. Diehm, Peter S. Vosler, Ulrich Harreus, Ulrich Kneser, Adriana C. Panayi
Summary: This study retrospectively analyzed the outcomes of OSA surgery at a national level, and identified risk factors for complications such as alkaline phosphatase levels, male gender, extreme BMI, and diabetes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Otorhinolaryngology
Min-Seok Rha, Yeonsu Jeong, Chang-Hoon Kim, Joo-Heon Yoon, Hyung-Ju Cho
Summary: This study found that the presence of mixed apnea (MA) events in patients with obstructive sleep apnea (OSA) leads to different clinical characteristics and surgical outcomes. The mixed group had a lower surgical success rate and smaller postoperative improvements in sleep apnea indices compared to the pure group. Logistic regression analysis confirmed that the presence of MA is an independent predictor of poor surgical outcomes in OSA patients.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Endocrinology & Metabolism
M. Leentjens, Abdulmohsen Alterki, Mohamed Abu-Farha, P. F. N. Bosschieter, CAL. de Raaff, CEE. de Vries, Eman Al Shawaf, Thangavel Alphonse Thanaraj, Irina Al-Khairi, Preethi Cherian, Arshad Channanath, Sina Kavalakatt, B. A. van Wagensveld, N. de Vries, Jehad Abubaker
Summary: This study found significantly increased levels of ANGPTL7 in both the circulation and adipose tissue of patients with OSA, which were associated with increased inflammation and OSA severity. Bariatric surgery was shown to significantly reduce ANGPTL7 levels and improve OSA.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Gabriela Bosco, Marta Morato, Nuria Perez-Martin, Andres Navarro, Miguel A. Racionero, Carlos O'Connor-Reina, Peter Baptista, Guillermo Plaza
Summary: The results suggest that one-stage multilevel surgery is a safe and successful treatment option for patients who cannot tolerate continuous positive airway pressure (CPAP) for obstructive sleep apnea-hypopnea syndrome (OSAHS), with significant improvements in postoperative AHI and ESS scores.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Otorhinolaryngology
Junbo Zhang, Jingjing Li, Guoping Yin, Xin Cao, Jingying Ye
Summary: The study found that velopharyngeal surgery has significant therapeutic effects on obstructive sleep apnea (OSA), with factors like tonsil size, percentage of time with oxygen saturation below 90%, vertical distance between lower margin of mandible and hyoid, and surgical methods being independently associated with treatment outcomes. The factors for surgical success differ in obese and non-obese patients, underlining the importance of considering obesity in pre-operative patient selection.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Somya Shankar, Annie E. Moroco, Zachary T. Elliott, Maurits Boon, Colin Huntley
Summary: This study retrospectively examined the health outcomes of patients with Trisomy 21 (T21) and obstructive sleep apnea (OSA) 10 years after their diagnosis of OSA. The results showed that patients with T21 and OSA had significantly higher incidence of adverse health outcomes in various cardiovascular, neurological, and endocrinological aspects. Patients who underwent sleep surgery had significantly reduced incidence of adverse health outcomes compared to those using continuous positive airway pressure.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Otorhinolaryngology
Yi Cai, Priyanka Tripuraneni, Arushi Gulati, Erika M. Stephens, Dang-Khoa Nguyen, Megan L. Durr, Jolie L. Chang
Summary: The treatment goals and values of adult patients with obstructive sleep apnea (OSA) vary based on age, symptoms, positive airway pressure (PAP) history, and severity of OSA. Understanding patient-specific goals is crucial in the shared decision-making process when choosing surgical or nonsurgical treatments.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Review
Health Care Sciences & Services
Sy Duong-Quy, Hoang Nguyen-Huu, Dinh Hoang-Chau-Bao, Si Tran-Duc, Lien Nguyen-Thi-Hong, Thai Nguyen-Duy, Tram Tang-Thi-Thao, Chandat Phan, Khue Bui-Diem, Quan Vu-Tran-Thien, Thu Nguyen-Ngoc-Phuong, Vinh Nguyen-Nhu, Huong Le-Thi-Minh, Timothy Craig
Summary: Obstructive Sleep Apnea (OSA) is a common disease that is often underestimated and undertreated in all age groups. Personalized diagnosis and treatment approaches are necessary for clinical practice due to morphological differences, clinical phenotype diversity, and variations in diagnosis and treatment of OSA in children and adults. Treatment should be based on individual tolerance to sleep-quality-related parameters, the harmful effects of hypoxia on the cardiovascular system, and patients' comorbidities.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Health Care Sciences & Services
Andreea Zabara-Antal, Ionela Grosu-Creanga, Mihai Lucian Zabara, Andrei Tudor Cernomaz, Bogdan Mihnea Ciuntu, Oana Melinte, Cristian Lupascu, Antigona Carmen Trofor
Summary: This review discusses the role of surgery in the treatment of sleep apnea and emphasizes the importance of individualized therapy. Depending on the type and severity of the apnea, the causal factor, obesity, hypercapnia, and associated pathologies, the optimal therapeutic method is determined for each individual case.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Otorhinolaryngology
Jerome R. Lechien, Carlos-Miguel Chiesa-Estomba, Nicolas Fakhry, Sven Saussez, Ibrahim Badr, Tareck Ayad, Younes Chekkoury-Idrissi, Antoine E. Melkane, Ahmed Bahgat, Lise Crevier-Buchman, Marc Blumen, Giovanni Cammaroto, Claudio Vicini, Stephane Hans
Summary: Transoral robotic surgery (TORS) for base of tongue (BOT) reduction in obstructive sleep apnea syndrome (OSAS) patients shows a high success rate and significant improvement in AHI, ESS, and lowest O-2 saturation.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Article
Medicine, General & Internal
Cristian Locci, Caterina Cenere, Giovanni Sotgiu, Mariangela Valentina Puci, Laura Saderi, Davide Rizzo, Francesco Bussu, Roberto Antonucci
Summary: Adenotonsillectomy (AT) has significant improvements in clinical and functional outcomes for children with obstructive sleep apnea syndrome (OSAS), although residual OSAS may occur in severe cases. Long-term post-surgical follow-up is highly recommended.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Su Young Jung, Young Min Mun, Gyu Man Lee, Sung Wan Kim
Summary: This study evaluated the effects of surgical treatment on fatigue, stress, and resilience in patients with obstructive sleep apnea. The results showed that multilevel surgery significantly improved fatigue and stress levels, and increased resilience in these patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Otorhinolaryngology
Joselina Antunes, Joao Orfao, Joao Rito, Cristina Adonis, Filipe Freire
Summary: This study investigates the effect of surgical treatment of OSA on sleep architecture and finds that the surgery can significantly improve sleep structure, allowing patients to spend more time in deep sleep.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Medicine, Research & Experimental
Alysha Rasool, Derrick R. Randall, Jason K. M. Chau
Summary: This study evaluated subjective swallowing function before and after sleep surgery in patients with OSA and found that subjective dysphagia peaked at 1 month postoperatively but returned to preoperative levels at 3 and 6 months postoperatively. Patients with pre-existing dysphagia showed improved swallowing function at 6 months postoperatively.
Article
Clinical Neurology
Hiwa Mohammadi, Ardalan Aarabi, Mohammad Rezaei, Habibolah Khazaie, Serge Brand
Summary: The study found that individuals with OSAS have significantly lower spindle density in N3 and shorter spindle duration in N2 compared to healthy controls. Furthermore, individuals with mild OSAS showed sleep spindle characteristics more similar to healthy controls, unlike those with moderate and severe OSAS.
FRONTIERS IN NEUROLOGY
(2021)
Article
Surgery
Richard J. Barth Jr, Eleah D. Porter, Julia L. Kelly, Sarah Y. Bessen, Lida B. Molloy, Joseph D. Phillips, Andrew P. Loehrer, Matthew Z. Wilson, Srinivas J. Ivatury, Sarah E. Billmeier, John D. Seigne, Sandra L. Wong, Ivy Wilkinson-Ryan
Summary: The aim of this study was to determine the frequency and reasons for long-term opioid prescriptions after surgery in the setting of guideline-directed prescribing and a high rate of excess opioid disposal. The results showed that 15.3% of patients filled an opioid prescription 3 to 12 months after surgery, mainly due to new painful medical conditions and new surgeries. The conclusion is that none of the patients in this study became persistent opioid users solely as a result of the opioid prescription given after their index surgery.
Article
Surgery
Andrew P. Loehrer, Louisa Chen, Qianfei Wang, Carrie H. Colla, Sandra L. Wong
Summary: The objective of this study was to examine the impact of rural residence on the access and outcomes of lung cancer surgery for Medicare beneficiaries. Lung cancer is the leading cause of cancer-related death in the United States, and rural patients have higher mortality rates. The study found that living in nonmetropolitan areas was associated with lower probability of cancer surgery, longer wait times for surgery, decreased use of minimally invasive surgery, and increased emergency department visits after surgery.
Article
Surgery
Andrew P. Loehrer, Priscila C. Cevallos, Rafael T. Jimenez, Sandra L. Wong
Summary: This study reviews the surgical literature on racial disparities in breast cancer mortality, specifically evaluating the inclusion, justification, and discussion of race and ethnicity. Among the 52 studies assessed, none provided a formal definition for race and/or ethnicity. Although 81% of studies discussed at least 1 potential driver of observed racial disparities, only 1 study explicitly named racism as a driver of racial disparities.
Article
Oncology
Heather G. Lyu, Pamela Lu, David A. Mahvi, Lindsay E. Y. Kuo, Sandra L. Wong, Chandrajit P. Raut, Nancy L. Cho
Summary: This study investigated the gender breakdown of presenters at recent Society of Surgical Oncology meetings. The results showed that the proportion of female presenters was comparable to the society demographics, but the representation of female senior authors was relatively low. Female first authorship was higher in poster sessions compared to other session types.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Education, Scientific Disciplines
Robert D. Shaw, Casey R. Lamb, Matthew C. Carroll, Sandra L. Wong, Kari M. Rosenkranz
Summary: The implementation of a standardized sub-internship curriculum in students' scheduled rotations can improve student confidence in their abilities related to the AAMC Core Entrustable Professional Activities for Entering Residency (CEPAERs).
JOURNAL OF SURGICAL EDUCATION
(2022)
Article
Medicine, Research & Experimental
Michael J. Hassett, Sandra Wong, Raymond U. Osarogiagbon, Jessica Bian, Don S. Dizon, Hannah Hazard Jenkins, Hajime Uno, Christine Cronin, Deborah Schrag
Summary: This research aims to improve symptom control and quality of life for cancer patients in the USA through an electronic symptom management program, and evaluate its impact through interdisciplinary collaboration and a pragmatic trial design.
Article
Surgery
Luke M. M. Funk, Justin Barr, Fabian M. M. Johnston, Brigitte K. K. Smith, Zara Cooper, Carla Pugh, Justin B. B. Dimick, Pierre-Alain Clavien, Thomas E. E. Read, Sandra L. L. Wong
Review
Oncology
Emily Z. Keung, Kate J. Krause, Jessica Maxwell, Carol D. Morris, Aimee M. Crago, Matthew T. Houdek, John Kane, Valerae Lewis, Dario Callegaro, Benjamin Miller, Alexander J. Lazar, Rebecca Gladdy, Chandrajit P. Raut, Nicola Fabbri, Waddah Al-Refaie, Mark Fairweather, Sandra L. Wong, Christina L. Roland
Summary: Regional lymph node metastasis (RLNM) is uncommon in patients with soft tissue sarcoma (STS), although certain STS subtypes are more prone to RLNM. The impact of node-positive disease on patient survival is still controversial. There is ongoing debate about the benefits of sentinel lymph node biopsy (SLNB) in STS patients. Further multicenter prospective studies are needed to determine the true incidence and potential benefits of SLNB in patients with clinically occult RLNM.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Editorial Material
Oncology
Emily Z. Keung, Kate J. Krause, Jessica Maxwell, Carol D. Morris, Aimee M. Crago, Matthew T. Houdek, John Kane, Valerae Lewis, Dario Callegaro, Benjamin Miller, Alexander J. Lazar, Rebecca Gladdy, Chandrajit P. Raut, Nicola Fabbri, Waddah Al-Refaie, Mark Fairweather, Sandra L. Wong, Christina L. Roland
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Medicine, General & Internal
Niveditta Ramkumar, Carrie H. Colla, Qianfei Wang, A. James O'Malley, Sandra L. Wong, Gabriel A. Brooks
Summary: Rural patients with colon cancer are more likely to undergo surgery but also more likely to undergo emergent surgery and less likely to have minimally invasive surgery compared to urban patients. The experiences of rural patients vary by race, with higher postoperative mortality for Black patients in rural areas.
Review
Surgery
Peter D. Congelosi, Matthew C. Carroll, Sandra L. Wong
Summary: This scoping review analyzed 12 studies and found that patient numeracy is generally poor, which has important implications for pre-operative risk understanding, accuracy of health measurement tools, and long-term surgical outcomes.
AMERICAN JOURNAL OF SURGERY
(2023)
Article
Health Care Sciences & Services
Niveditta Ramkumar, Qianfei Wang, Gabriel A. Brooks, Anna N. A. Tosteson, Sandra L. Wong, Andrew P. Loehrer
Summary: This study examined the association between rural residence and the use of palliative care and hospice services. The results showed that patients in small town and rural areas had lower odds of receiving hospice care compared to those in metropolitan areas. This highlights the need to improve access to hospice services in rural communities and enhance the quality of end-of-life care for patients.
JOURNAL OF RURAL HEALTH
(2023)
Article
Gastroenterology & Hepatology
Ingrid Woelfel, Daria Faulkner, Sandra Wong, Kenneth Washburn, Austin Schenk
Summary: Although patients and physicians have different perceptions of success, there is significant agreement in their definitions, including avoidance of death, restoration of physical and mental function, return to society, acquisition of new health care knowledge, and open communication between patient and physician. Patients emphasize relief from worry about their future health status, while physicians highlight decreased health care costs. Patients understand that a liver transplant does not have to be perfect, free from complications, to be considered successful.
LIVER TRANSPLANTATION
(2023)
Article
Oncology
Reagan A. Collins, Salma A. Sheriff, Christopher Yoon, Adrianne N. Cobb, Anai N. Kothari, Lisa A. Newman, Lesly A. Dossett, Alliric I. Willis, Sandra L. Wong, Callisia N. Clarke
Summary: This study assesses the racial and ethnic representation in medical students, general surgery residents, and complex general surgical oncology fellows. The results showed a decrease in minority representation at every stage of surgical oncology training, with underrepresentation of Black/African American and Hispanic/Latino individuals compared to the 2020 Census data. Efforts are needed to address barriers for Black/African American and Hispanic/Latino individuals applying to complex general surgical oncology fellowships.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Nigel S. Key, Alok A. Khorana, Nicole M. Kuderer, Kari Bohlke, Agnes Y. Lee, Juan I. Arcelus, Sandra L. Wong, Edward P. Balaban, Christopher R. Flowers, Leigh E. Gates, Ajay K. Kakkar, Margaret A. Tempero, Shilpi Gupta, Gary H. Lyman, Anna Falanga
Summary: This article aims to update the ASCO venous thromboembolism (VTE) guideline. After identifying potentially practice-changing clinical trials, an updated systematic review was conducted for two guideline questions: perioperative thromboprophylaxis and treatment of VTE. The results highlighted the safety and effectiveness of direct factor Xa inhibitors and apixaban in extended thromboprophylaxis after surgery and in the treatment of VTE.
JOURNAL OF CLINICAL ONCOLOGY
(2023)