Clonal deletion and the fate of autoreactive thymocytes that survive negative selection

Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens

(2012) A. Y. W. Suen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Medullary interplay for central tolerance

(2011) Y. Takahama   BLOOD

Signaling in thymic selection

(2011) Nicholas RJ Gascoigne et al.   CURRENT OPINION IN IMMUNOLOGY

A Novel TCR Transgenic Model Reveals That Negative Selection Involves an Immediate, Bim-Dependent Pathway and a Delayed, Bim-Independent Pathway

(2010) Damian Kovalovsky et al.   PLoS One

The Ligase PIAS1 Restricts Natural Regulatory T Cell Differentiation by Epigenetic Repression

(2010) B. Liu et al.   SCIENCE

PD-1 signaling in primary T cells

(2009) James L. Riley   IMMUNOLOGICAL REVIEWS

Bim-Mediated Apoptosis Is Not Necessary for Thymic Negative Selection to Ubiquitous Self-Antigens

(2009) Q. Hu et al.   JOURNAL OF IMMUNOLOGY

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla

(2008) Tom M. McCaughtry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

(2008) Takeshi Egawa et al.   NATURE IMMUNOLOGY

Central tolerance: what have we learned from mice?

(2008) Tom M. McCaughtry et al.   Seminars in Immunopathology