Journal
NATURE IMMUNOLOGY
Volume 12, Issue 1, Pages 16-17Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ni0111-16
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T(H)2 cells control immune responses to helminth infection and contribute to the development of allergic asthma. A single intronic enhancer element in Il4 can regulate T(H)2 differentiation and susceptibility to allergic asthma via interaction with the transcription factor GATA-3.
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