4.7 Editorial Material

Don't move: LRRK2 arrests NFAT in the cytoplasm

Journal

NATURE IMMUNOLOGY
Volume 12, Issue 11, Pages 1029-1030

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NATURE PUBLISHING GROUP
DOI: 10.1038/ni.2139

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The kinase LRRK2 is a risk factor for inflammatory bowel disease. New data show that LLRK2 blocks the transport of NFAT to the nucleus and that LLRK2 deficiency results in enhanced susceptibility to experimental colitis in mice.

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