4.7 Editorial Material

IRF1: a deus ex machina in T(H)1 differentiation

Journal

NATURE IMMUNOLOGY
Volume 9, Issue 1, Pages 9-10

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NATURE PUBLISHING GROUP
DOI: 10.1038/ni0108-9

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The cytokines IFN-gamma and IL-12, a long with the transcription factors STAT4 and T-bet, are necessary for driving T(H)1 development. Fresh data now indicate that the transcription factor IRF1 is also essential in this process.

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