Journal
NATURE GENETICS
Volume 46, Issue 4, Pages 321-323Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.2930
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A new study explores the ancient oral microbiome from the well-preserved dental calculus samples of four human individuals who lived during medieval times, using a suite of genomic, proteomic and microscopic approaches. The authors investigate the evolution of dental pathogens by reconstructing the genome of the periodontal pathogen Tannerella forsythia and also identify antibiotic resistance genes, bacterial virulence factors and host immune defense proteins.
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