Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1

Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

(2011) Ian P. M. Tomlinson et al.   PLoS Genetics

Identification of candidate predisposing copy number variants in familial and early-onset colorectal cancer patients

(2010) Ramprasath Venkatachalam et al.   INTERNATIONAL JOURNAL OF CANCER

Germline Bone Morphogenesis Protein Receptor 1A Mutation Causes Colorectal Tumorigenesis in Hereditary Mixed Polyposis Syndrome

(2009) Peh Yean Cheah et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer

(2009) I P M Tomlinson et al.   BRITISH JOURNAL OF CANCER

PTEN hamartoma tumor syndrome: An overview

(2009) Judith A Hobert et al.   GENETICS IN MEDICINE

Deciphering the genetics of hereditary non-syndromic colorectal cancer

(2008) Eli Papaemmanuil et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Sporadic and Syndromic Hyperplastic Polyps and Serrated Adenomas of the Colon: Classification, Molecular Genetics, Natural History, and Clinical Management

(2008) James E. East et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice

(2008) Stefania Segditsas et al.   HUMAN MOLECULAR GENETICS