Insights into mucopolysaccharidosis I from the structure and action of α-L-iduronidase

Human α-l-iduronidase uses its ownN-glycan as a substrate-binding and catalytic module

(2013) Nobuo Maita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological chaperones facilitate the post-ER transport of recombinant N370S mutant β-glucocerebrosidase in plant cells: Evidence that N370S is a folding mutant

(2012) Gholamreza Babajani et al.   MOLECULAR GENETICS AND METABOLISM

Influence of an ER-retention signal on the N-glycosylation of recombinant human α-l-iduronidase generated in seeds of Arabidopsis

(2012) Xu He et al.   PLANT MOLECULAR BIOLOGY

Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease

(2012) Xu He et al.   Nature Communications

Conformational Analyses of the Reaction Coordinate of Glycosidases

(2011) Gideon J. Davies et al.   ACCOUNTS OF CHEMICAL RESEARCH

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification and Characterization of Pharmacological Chaperones to Correct Enzyme Deficiencies in Lysosomal Storage Disorders

(2011) Kenneth J. Valenzano et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Graphical analysis of pH-dependent properties of proteins predicted using PROPKA

(2011) Michał Rostkowski et al.   BMC STRUCTURAL BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification of Pharmacological Chaperones for Gaucher Disease and Characterization of Their Effects on β-Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry

(2008) Michael B. Tropak et al.   CHEMBIOCHEM

The mucopolysaccharidoses: a success of molecular medicine

(2008) Lorne A. Clarke   EXPERT REVIEWS IN MOLECULAR MEDICINE

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols