Active site profiling reveals coupling between domains in SRC-family kinases
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Active site profiling reveals coupling between domains in SRC-family kinases
Authors
Keywords
-
Journal
Nature Chemical Biology
Volume 9, Issue 1, Pages 43-50
Publisher
Springer Nature
Online
2012-11-12
DOI
10.1038/nchembio.1118
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cell-Based Proteome Profiling of Potential Dasatinib Targets by Use of Affinity-Based Probes
- (2012) Haibin Shi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles
- (2012) George Georghiou et al. Nature Chemical Biology
- The secret life of kinases: functions beyond catalysis
- (2011) Jens Rauch et al. Cell Communication and Signaling
- In Situ Kinase Profiling Reveals Functionally Relevant Properties of Native Kinases
- (2011) Matthew P. Patricelli et al. CHEMISTRY & BIOLOGY
- Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms
- (2011) Natalia Jura et al. MOLECULAR CELL
- Activation State-Dependent Binding of Small Molecule Kinase Inhibitors: Structural Insights from Biochemistry
- (2010) Lisa M. Wodicka et al. CHEMISTRY & BIOLOGY
- Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation Mechanism
- (2010) John J. Alvarado et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activity-based Proteomics of Enzyme Superfamilies: Serine Hydrolases as a Case Study
- (2010) Gabriel M. Simon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
- (2010) Poulikos I. Poulikakos et al. NATURE
- RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
- (2010) Georgia Hatzivassiliou et al. NATURE
- A chemical and phosphoproteomic characterization of dasatinib action in lung cancer
- (2010) Jiannong Li et al. Nature Chemical Biology
- Click Chemistry and Bioorthogonal Reactions: Unprecedented Selectivity in the Labeling of Biological Molecules
- (2009) Michael D. Best BIOCHEMISTRY
- Equally Potent Inhibition of c-Src and Abl by Compounds that Recognize Inactive Kinase Conformations
- (2009) M. A. Seeliger et al. CANCER RESEARCH
- A non-catalytic function of the Src family tyrosine kinases controls prolactin-induced Jak2 signaling
- (2009) José Manuel García-Martínez et al. CELLULAR SIGNALLING
- Allosteric networks governing regulation and catalysis of Src-family protein tyrosine kinases: Implications for disease-associated kinases
- (2009) Heung-Chin Cheng et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Hybrid Compound Design To Overcome the Gatekeeper T338M Mutation in cSrc#
- (2009) Matthäus Getlik et al. JOURNAL OF MEDICINAL CHEMISTRY
- A new screening assay for allosteric inhibitors of cSrc
- (2009) Jeffrey R Simard et al. Nature Chemical Biology
- Inhibitor hijacking of Akt activation
- (2009) Tatsuya Okuzumi et al. Nature Chemical Biology
- Proteomics strategy for quantitative protein interaction profiling in cell extracts
- (2009) Kirti Sharma et al. NATURE METHODS
- Src kinases as therapeutic targets for cancer
- (2009) Lori C. Kim et al. Nature Reviews Clinical Oncology
- HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis
- (2008) Georgyi V. Los et al. ACS Chemical Biology
- Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry
- (2008) Benjamin F. Cravatt et al. Annual Review of Biochemistry
- Structure and dynamic regulation of Src-family kinases
- (2008) J. R. Engen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Small Molecule Recognition of c-Src via the Imatinib-Binding Conformation
- (2008) Arvin C. Dar et al. CHEMISTRY & BIOLOGY
- Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib
- (2008) Oliver Hantschel et al. LEUKEMIA & LYMPHOMA
- A quantitative analysis of kinase inhibitor selectivity
- (2008) Mazen W Karaman et al. NATURE BIOTECHNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started