Multi-talented MCAK: Microtubule depolymerizer with a strong grip

The bidirectional depolymerizer MCAK generates force by disassembling both microtubule ends

(2011) Yusuke Oguchi et al.   NATURE CELL BIOLOGY

Mitotic force generators and chromosome segregation

(2010) Gul Civelekoglu-Scholey et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tubulin depolymerization may be an ancient biological motor

(2010) J. R. McIntosh et al.   JOURNAL OF CELL SCIENCE

Kinetochores’ gripping feat: conformational wave or biased diffusion?

(2010) Charles L. Asbury et al.   TRENDS IN CELL BIOLOGY

The Ndc80 Kinetochore Complex Forms Load-Bearing Attachments to Dynamic Microtubule Tips via Biased Diffusion

(2009) Andrew F. Powers et al.   CELL

Direct observation of the binding state of the kinesin head to the microtubule

(2009) Nicholas R. Guydosh et al.   NATURE

Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK

(2009) Jeremy R Cooper et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

XMAP215 Is a Processive Microtubule Polymerase

(2008) Gary J. Brouhard et al.   CELL

Kinesin-8 from Fission Yeast: A Heterodimeric, Plus-End–directed Motor that Can Couple Microtubule Depolymerization to Cargo Movement

(2008) Paula M. Grissom et al.   MOLECULAR BIOLOGY OF THE CELL