A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Physiological function and molecular basis of STIM1-mediated calcium entry in immune cells

(2009) Yoshihiro Baba et al.   IMMUNOLOGICAL REVIEWS

The functional network of ion channels in T lymphocytes

(2009) Michael D. Cahalan et al.   IMMUNOLOGICAL REVIEWS

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

(2009) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Intracellular Loop of Orai1 Plays a Central Role in Fast Inactivation of Ca2+Release-activated Ca2+Channels

(2009) Sonal Srikanth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

(2009) Joseph P. Yuan et al.   NATURE CELL BIOLOGY

STIMulating store-operated Ca2+ entry

(2009) Michael D. Cahalan   NATURE CELL BIOLOGY

STIM1 gates the store-operated calcium channel ORAI1 in vitro

(2009) Yubin Zhou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels

(2009) F. M. Mullins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calmodulin Binding to the Polybasic C-Termini of STIM Proteins Involved in Store-Operated Calcium Entry†

(2008) Mikael C. Bauer et al.   BIOCHEMISTRY

Dynamic Coupling of the Putative Coiled-coil Domain of ORAI1 with STIM1 Mediates ORAI1 Channel Activation

(2008) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy

(2008) Laura Navarro-Borelly et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hair Loss and Defective T- and B-Cell Function in Mice Lacking ORAI1

(2008) Y. Gwack et al.   MOLECULAR AND CELLULAR BIOLOGY

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

(2008) Riina M. Luik et al.   NATURE

Calcium signaling in immune cells

(2008) Monika Vig et al.   NATURE IMMUNOLOGY