4.8 Article

SNP imputation in association studies

Journal

NATURE BIOTECHNOLOGY
Volume 27, Issue 4, Pages 349-351

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nbt0409-349

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Only a subset of single-nucleotide polymorphisms (SNPs) can be genotyped in genome-wide association studies. Imputation methods can infer the alleles of 'hidden' variants and use those inferences to test the hidden variants for association.

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