Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells
Authors
Keywords
-
Journal
NATURE
Volume 553, Issue 7687, Pages 171-177
Publisher
Springer Nature
Online
2018-01-03
DOI
10.1038/nature25154
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks
- (2016) David W. Wyatt et al. MOLECULAR CELL
- p53 downregulates the Fanconi anaemia DNA repair pathway
- (2016) Sara Jaber et al. Nature Communications
- The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription
- (2015) Rebekka A. Schwab et al. MOLECULAR CELL
- The Fanconi Anemia Pathway Protects Genome Integrity from R-loops
- (2015) María L. García-Rubio et al. PLoS Genetics
- Aldehyde dehydrogenase-2 polymorphism contributes to the progression of bone marrow failure in children with idiopathic aplastic anaemia
- (2014) Nozomu Kawashima et al. BRITISH JOURNAL OF HAEMATOLOGY
- Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis
- (2014) Nina Cabezas-Wallscheid et al. Cell Stem Cell
- Maternal Aldehyde Elimination during Pregnancy Preserves the Fetal Genome
- (2014) Nina Oberbeck et al. MOLECULAR CELL
- Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining
- (2014) Hind Ghezraoui et al. MOLECULAR CELL
- Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells
- (2014) Johanna Flach et al. NATURE
- Genome sequencing of normal cells reveals developmental lineages and mutational processes
- (2014) Sam Behjati et al. NATURE
- Dominance of the Inactive Asian Variant Over Activity and Protein Contents of Mitochondrial Aldehyde Dehydrogenase 2 in Human Liver
- (2013) Ching-Long Lai et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Why does the bone marrow fail in Fanconi anemia?
- (2013) J. I. Garaycoechea et al. BLOOD
- Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients
- (2013) A. Hira et al. BLOOD
- SLAM Family Markers Resolve Functionally Distinct Subpopulations of Hematopoietic Stem Cells and Multipotent Progenitors
- (2013) Hideyuki Oguro et al. Cell Stem Cell
- Massively Parallel Sequencing Reveals the Complex Structure of an Irradiated Human Chromosome on a Mouse Background in the Tc1 Model of Down Syndrome
- (2013) Susan M. Gribble et al. PLoS One
- Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function
- (2012) Juan I. Garaycoechea et al. NATURE
- Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
- (2011) Brad Dykstra et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
- (2011) Frédéric Langevin et al. NATURE
- Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
- (2011) W. W. Pang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair
- (2011) D. T. Long et al. SCIENCE
- MPprimer: a program for reliable multiplex PCR primer design
- (2010) Zhiyong Shen et al. BMC BIOINFORMATICS
- 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
- (2010) Samuel F. Bunting et al. CELL
- A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal
- (2010) Michael Milyavsky et al. Cell Stem Cell
- Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis
- (2010) Mary Mohrin et al. Cell Stem Cell
- Differential Requirement for H2AX and 53BP1 in Organismal Development and Genome Maintenance in the Absence of Poly(ADP)ribosyl Polymerase 1
- (2010) B. Orsburn et al. MOLECULAR AND CELLULAR BIOLOGY
- Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia
- (2010) Adele Adamo et al. MOLECULAR CELL
- Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway
- (2010) P. Pace et al. SCIENCE
- A large genome center's improvements to the Illumina sequencing system
- (2008) Michael A Quail et al. NATURE METHODS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now