Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas

Pancreatic Cancer Genetics

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Reparative inflammation takes charge of tissue regeneration

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Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A

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The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

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Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice

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Tumor Necrosis Factor Suppresses NR5A2 Activity and Intestinal Glucocorticoid Synthesis to Sustain Chronic Colitis

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Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution

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Nr5a2heterozygosity sensitises to, and cooperates with, inflammation inKRasG12V-driven pancreatic tumourigenesis

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LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function

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Gene expression dynamics after murine pancreatitis unveils novel roles for Hnf1α in acinar cell homeostasis

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Immunity, Inflammation, and Cancer

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A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

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