Killing from the inside

Transformation-Associated Changes in Sphingolipid Metabolism Sensitize Cells to Lysosomal Cell Death Induced by Inhibitors of Acid Sphingomyelinase

(2013) Nikolaj H.T. Petersen et al.   CANCER CELL

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): A Novel Pharmacological Group of Drugs with Broad Clinical Applications

(2010) Johannes Kornhuber et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion

(2010) Misbaudeen Abdul-Hammed et al.   JOURNAL OF LIPID RESEARCH

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

(2010) Thomas Kirkegaard et al.   NATURE

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sensitization to the Lysosomal Cell Death Pathway by Oncogene-Induced Down-regulation of Lysosome-Associated Membrane Proteins 1 and 2

(2008) N. Fehrenbacher et al.   CANCER RESEARCH

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE