Editorial Material
Immunology
Joanna R. Groom, James E. Vince
Summary: A T(H)17 cell NLRP3-caspase-8-caspase-3-GSDME axis is found to release the alarmin IL-1 alpha without inducing cell death.
Article
Biochemistry & Molecular Biology
Rachel R. Rock, Peter J. Turnbaugh
Summary: Aging is associated with increased risk of diseases and the role of the microbiome in aging is understudied. This Essay highlights recent progress in understanding the contribution of the microbiome to aging and age-associated diseases. The need to consider sexually dimorphic phenotypes and the broad implications for interdisciplinary research are also discussed.
Article
Biotechnology & Applied Microbiology
Ghaith Zamzam, Christopher W. J. Lee, Fiona Milne, Jenna Etsell, Dion G. Durnford
Summary: The mass cultivation of algal biomass faces challenges due to the underdeveloped concept of aging, which can affect biomass and bioproduct accumulation. This study examines the effects of acetate content on the longevity of Chlamydomonas reinhardtii and finds that acetate influences biomass accumulation, chlorophyll content, starch accumulation, and cell survival. High acetate levels are correlated with accelerated senescence and death.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Review
Biology
Eisuke Tasaki, Mamoru Takata, Kenji Matsuura
Summary: Lifespan varies greatly across different organisms, with some extending longevity through trade-offs between reproduction and longevity, while social insect reproductives are exceptions, exhibiting both high reproductive outputs and long lives, attracting much attention for the reasons and mechanisms behind their extended lifespans.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Juliane Hartke, Alejandro Ceron-Noriega, Marah Stoldt, Tom Sistermans, Marion Kever, Jenny Fuchs, Falk Butter, Susanne Foitzik
Summary: Parasites with complex life cycles often manipulate the phenotype of their intermediate hosts to increase transmission to their definitive hosts. Infection with Anomotaenia brevis, a cestode that uses Temnothorax nylanderi ants as intermediate hosts, leads to extended host lifespan and changes in behavior, morphology, and coloration. The parasite releases proteins into its host that may explain these changes, with two antioxidants being the most abundant among them.
Review
Biology
Bruce Zhang, David Gems
Summary: Evolutionary medicine suggests that modern diseases may arise due to mismatches between our current environment and our evolved biology. Restoring commensal microbes and helminths may have therapeutic effects on allergic and autoimmune conditions, as well as age-related diseases such as inflammaging. Further research is needed to explore the potential broad-spectrum protective effects of worm infections against age-related illnesses.
Article
Obstetrics & Gynecology
P. Lehert, P. Arvis, C. Avril, N. Massin, J. Parinaud, G. Porcu, C. Rongieres, P. Sagot, R. Wainer, T. D'Hooghe
Summary: The PROsPeR score can effectively predict live birth outcomes in patients with poor ovarian response, showing fair discrimination and calibration. The score can be used to assess the likelihood of live birth based on female age, serum AMH, and PNO, providing a valuable tool for comparing outcomes in different populations.
HUMAN REPRODUCTION
(2021)
Article
Construction & Building Technology
Meichen Liang, Meng Guo, Yiqiu Tan, Shuxin He, Xiuli Du
Summary: An additive called BARAA, which resists all-weather ageing, has been developed in this study. It has excellent anti-ageing performance and fewer side effects, and is able to double the service life of bitumen. The study also found that the anti-ageing index and influence index can quantitatively evaluate the performance of anti-ageing additives.
INTERNATIONAL JOURNAL OF PAVEMENT ENGINEERING
(2023)
Review
Hematology
J. L. Vives Corrons, L. Berga Casafont, E. Feliu Frasnedo
Summary: The average lifespan of a human red blood cell is around 120 days. At this point, the cell is usually worn out and undergoes phagocytosis by macrophages in the spleen or liver, where iron is recycled and hem molecule is eliminated as bilirubin.
ANNALS OF HEMATOLOGY
(2021)
Review
Construction & Building Technology
Ingrid Gabrielle do Nascimento Camargo, Taha Ben Dhia, Amara Loulizi, Bernard Hofko, Johannes Mirwald
Summary: Asphalt binder ageing makes it brittle and prone to cracking, with the rate depending on factors like chemical composition and mix design. Anti-ageing additives are used to prevent ageing, with the selection process involving iterative steps. Evaluation of the additives' appropriateness can be done through rheology performance parameters before and after ageing.
ROAD MATERIALS AND PAVEMENT DESIGN
(2021)
Article
History & Philosophy Of Science
Christopher S. Wareham
Summary: The article discusses two types of concerns in ethical debates about extending human lifespan: one focusing on the value of living longer, the other on the value of aiming for longer life. The author argues that features of human psychology and life structure should also be taken into account when considering how long one should aim to live.
HISTORY AND PHILOSOPHY OF THE LIFE SCIENCES
(2021)
Review
Ecology
Ragan M. Callaway, Jacob E. Lucero, Jose L. Hierro, C. J. Lortie
Summary: This study reevaluates the evolution of increased competitive ability (EICA) theory by using meta-analysis. By testing Leaf-Specific Mass as a response trait and partitioning competitive effect and competitive tolerance measures, the study finds evidence consistent with the classic trade-off inherent to EICA, showing that plants from non-native ranges impose greater competitive effects and are less quantitatively defended than plants from native ranges.
Article
Area Studies
Grant W. Walton, Husnia Hushang
Summary: This article examines the sustainability of anti-corruption funding during and after the RAMSI intervention in Solomon Islands and finds that political elites have maintained their commitment to anti-corruption policy transfer in the post-RAMSI era, with funding levels surpassing those of neighboring Papua New Guinea.
ASIA & THE PACIFIC POLICY STUDIES
(2022)
Article
Immunology
Lei Wang, Erik A. M. Verschuuren, Davy Paap, Christien Rondaan, Elisabeth Raveling-Eelsing, Siqi Liu, Johanna Westra, Nicolaas A. Bos
Summary: The average age of lung transplant recipients has increased significantly over time. Elderly recipients are more at risk of developing herpes zoster (HZ) and have poorer vaccination responses compared to younger individuals. The study focused on the relationship between immune responses to HZ vaccination and T and B cell subsets, particularly in elderly individuals.
Review
Biochemistry & Molecular Biology
Sarah Bouzroud, Ezzouhra El Maaiden, Mansour Sobeh, Nawal Merghoub, Hassan Boukcim, Lamfeddal Kouisni, Youssef El Kharrassi
Summary: Plants are a valuable source of bioactive compounds for cosmetic products. Plant tissue culture techniques offer a sustainable method to produce these compounds independently of external factors. This work explores the use of biotechnological tools and approaches to increase production and develop sustainable plant-derived cosmetic products.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)