Article
Critical Care Medicine
Victor A. Convertino, Patrick Thompson, Natalie J. Koons, Tuan D. Le, J. Brian Lanier, Sylvain Cardin
Summary: This study aimed to test the ability of shock index (SI) in predicting hemodynamic decompensation. Through experiments on 172 subjects, it was found that SI delayed the detection of reduced central blood volume and could not differentiate individuals with varying tolerances to central hypovolemia.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2023)
Article
Clinical Neurology
Anna Ramos, Waldo R. Guerrero, Natalia Perez de la Ossa
Summary: This article reviews the importance of prehospital organization in the treatment of acute stroke, emphasizing the need for rapid treatment of large vessel occlusion. It also discusses different prehospital transfer protocols that may improve treatment outcomes.
Article
Clinical Neurology
Henry Zhao, Karen Smith, Stephen Bernard, Michael Stephenson, Henry Ma, Ronil Chandra, Thanh Phan, Christopher F. Bladin, Leonid Churilov, Douglas Crompton, Helen M. Dewey, Tissa Wijeratne, Geoffrey Cloud, Vincent Thijs, Timothy J. Kleinig, Jo Lyn Ng, Cameron Williams, Fana Alemseged, Felix Ng, Peter J. Mitchell, Mark W. Parsons, Nawaf Yassi, Stephen M. Davis, Bruce C. Campbell
Summary: Implementation of the ACT-FAST algorithm provides more stroke patients with faster EVT and avoids secondary transfers, with the benefits outweighing the disadvantages, despite some shortcomings.
Article
Clinical Neurology
Tove Almqvist, Anna Falk Delgado, Christina Sjoestrand, Niaz Ahmed, Annika Berglund, Einar Eriksson, Michael V. Mazya
Summary: The implementation of the Stockholm Stroke Triage System (SSTS) did not significantly affect the timing and outcomes of acute intracerebral hemorrhage (ICH) neurosurgery. However, it successfully directed more patients with neurosurgical indications to the comprehensive stroke center.
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS
(2023)
Article
Clinical Neurology
Kristin Tveitan Larsen, Maiken Nordahl Selseth, Silje Holt Jahr, Vigdis Hillestad, Nojoud Koubaa, Else Charlotte Sandset, Ole Morten Ronning, Espen Saxhaug Kristoffersen
Summary: This study investigated the relationship between prehospital blood pressure (BP) and clinical and radiological outcomes in acute intracerebral hemorrhage patients. The results showed that elevated prehospital BP parameters were associated with in-hospital death and hematoma expansion. Changes in prehospital BP were not consistently associated with outcome. A possible U-shaped association between prehospital BP and in-hospital death needs further investigation.
Article
Critical Care Medicine
Andrew J. Latimer, Catherine R. Counts, Molly Van Dyke, Natalie Bulger, Charles Maynard, Thomas D. Rea, Peter J. Kudenchuk, Richard B. Utarnachitt, Jennifer Blackwood, Amy J. Poel, Saman Arbabi, Michael R. Sayre
Summary: This study analyzed the application of the compensatory reserve index (CRI) in trauma patients. The study found that lower CRI-T values were associated with an increased likelihood of hemorrhagic shock and could be used as a predictor for hemorrhagic shock, but it was not as effective as prehospital vital signs in diagnosing hemorrhagic shock.
Article
Medicine, General & Internal
Luis D. Pacheco, Rebecca G. Clifton, George R. Saade, Steven J. Weiner, Samuel Parry, John M. Thorp Jr, Monica Longo, Ashley Salazar, Wendy Dalton, Alan T. N. Tita, Cynthia Gyamfi-Bannerman, Suneet P. Chauhan, Torri D. Metz, Kara Rood, Dwight J. Rouse, Jennifer L. Bailit, William A. Grobman, Hyagriv N. Simhan, George A. Macones
Summary: Prophylactic use of tranexamic acid during cesarean delivery did not lead to a significantly lower risk of maternal death or blood transfusion than placebo.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Review
Critical Care Medicine
Zaffer Qasim, Frank K. Butler, John B. Holcomb, Joseph G. Kotora, Brian J. Eastridge, Karim Brohi, Thomas M. Scalea, C. William Schwab, Brendon Drew, Jennifer Gurney, Jan O. Jansen, Lewis J. Kaplan, Matthew J. Martin, Todd E. Rasmussen, Stacy A. Shackelford, Eric A. Bank, Darren Braude, Megan Brenner, Francis X. Guyette, Bellal Joseph, William R. Hinckley, Jason L. Sperry, Juan Duchesne
Summary: Hemorrhage, especially noncompressible torso hemorrhage, is a major cause of prehospital death from trauma in the United States and globally. Some severely injured patients either die at the scene or develop irreversible hemorrhagic shock before they can receive proper hospital care, leading to poor outcomes. This paper discusses the need for trauma systems to adapt in order to provide potentially life-saving resuscitation and hemorrhage control interventions closer to the point-of-injury for select patients, and proposes a mechanism for training and incorporating prehospital advanced resuscitative care teams to deliver these interventions.
Article
Emergency Medicine
Laura Pariente Juste, Maylin Koo Gomez, Antonia Bonet Burguera, Raquel Reyes Garcia, Lourdes Perez Garcia, Irene Macia Tejada
Summary: This study examined the association between shock index and the need for massive blood transfusion, duration of hospital stay, and mortality in polytrauma patients. The findings suggest that shock index is a useful predictor to identify polytrauma patients who require early blood transfusion for optimal treatment, while other indicators may be better for predicting mortality and hospital stay.
Article
Cardiac & Cardiovascular Systems
Kristin Tveitan Larsen, Else Charlotte Sandset, Maiken Nordahl Selseth, Silje Holt Jahr, Nojoud Koubaa, Vigdis Hillestad, Espen Saxhaug Kristoffersen, Ole Morten Ronning
Summary: This study aimed to explore the interaction between antithrombotic treatment and prehospital blood pressure in patients with acute intracerebral hemorrhage. The findings showed that compared to patients without antithrombotic treatment, patients with antithrombotic treatment had stronger associations between high prehospital systolic blood pressure and in-hospital mortality, likelihood of disability improvement, and hematoma volume.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Neuroimaging
Hayato Araki, Kazutaka Uchida, Shinichi Yoshimura, Kaoru Kurisu, Nobuaki Shime, Shigeyuki Sakamoto, Shiro Aoki, Nobuhiko Ichinose, Yosuke Kajihara, Atsushi Tominaga, Hiromitsu Naka, Tatsuya Mizoue, Masayuki Sumida, Nobuyuki Hirotsune, Eiichi Nomura, Toshinori Matsushige, Junichi Kanazawa, Yukio Kato, Yukihiko Kawamoto, Kazuhiko Kuroki, Takeshi Morimoto
Summary: The study found that the use of the Japan Urgent Stroke Triage (JUST) score can effectively improve prehospital management and preparation time for patients with acute stroke, increasing the success rate of the first request to the hospital. Although the implementation of the JUST score shortened the door-to-puncture time, the prognosis for patients with acute LVO remained unchanged.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Clinical Neurology
Kazutaka Uchida, Junichi Kouno, Shinichi Yoshimura, Norito Kinjo, Fumihiro Sakakibara, Hayato Araki, Takeshi Morimoto
Summary: Recent advancements in machine learning have led to its application in developing a prehospital stroke scale. The study involved a multi-center cohort study with training data from 8 centers in Japan and testing data from 13 centers. Three different ML algorithms were used to develop models, which showed stable and superior predictive abilities in the test cohort, particularly in classifying LVO.
TRANSLATIONAL STROKE RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
Vaidehi V. Paranjape, Natalia Henao-Guerrero, Giulio Menciotti, Siddharth Saksena, Manuela Agostinho
Summary: Using general anesthesia on animals causes significant changes to the heart and blood vessels. Noninvasive electrical cardiometry (EC) can be used to monitor hemodynamics in anesthetized dogs and show trends in cardiac output (CO) measured using pulmonary artery thermodilution (PATD). EC consistently underpredicts CO values compared to PATD, but has a better performance during acute blood loss. This noninvasive method can potentially benefit patient care quality in clinics by monitoring hemodynamic trends and guiding diagnosis and treatment of cardiovascular complications.
Article
Medicine, General & Internal
Robin D. Lokerman, Eveline A. J. van Rein, Job F. Waalwijk, Rogier van der Sluijs, Roderick M. Houwert, Koen W. W. Lansink, Michael J. R. Edwards, Risco van Vliet, Thijs F. Verhagen, Nicolette Diets-Veenendaal, Luke P. H. Leenen, Mark van Heijl
Summary: In this quality improvement study, implementation of the trauma triage intervention was associated with a statistically significant decrease in the risk of undertriage, while the risk of overtriage remained unchanged.
Article
Computer Science, Information Systems
Jacob P. Kimball, Jonathan S. Zia, Sungtae An, Christopher Rolfes, Jin-Oh Hahn, Michael N. Sawka, Omer T. Inan
Summary: This study developed a global model incorporating ECG, SCG and RPPG features for estimating individual-specific decompensation from progressive relative and absolute hypovolemia and resuscitation. It demonstrated SCG as the most important modality to predict decompensation, the efficacy of random forest models trained on different data subsets, and the increase in prediction accuracy for different forms of hypovolemia and resuscitation when adding training data from two discrete forms of hypovolemia.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2021)
Article
Critical Care Medicine
Natalie J. Koons, Betty Nguyen, Mithun R. Suresh, Carmen Hinojosa-Laborde, Victor A. Convertino
Article
Critical Care Medicine
Victor A. Convertino, Mallory R. Wampler, Michael Johnson, Abdul Alarhayem, Tuan D. Le, Susannah Nicholson, John G. Myers, Kevin K. Chung, Katie R. Struck, Camaren Cuenca, Brian J. Eastridge
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2020)
Article
Critical Care Medicine
Avi Benov, Anat Brand, Tal Rozenblat, Ben Antebi, Anat Ben-Ari, Rotem Amir-Keret, Roy Nadler, Jacob Chen, Kevin K. Chung, Victor A. Convertino, Haim Paran
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2020)
Article
Critical Care Medicine
Natalie J. Koons, Gregory A. Owens, Donald L. Parsons, Steven G. Schauer, Jerome L. Buller, Victor A. Convertino
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2020)
Article
Critical Care Medicine
Taylor E. Schlotman, Mithun R. Suresh, Natalie J. Koons, Jeffrey T. Howard, Alicia M. Schiller, Sylvain Cardin, Victor A. Convertino
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2020)
Article
Multidisciplinary Sciences
Morten Zaar, Maryanne C. Herzig, Chriselda G. Fedyk, Robbie K. Montgomery, Nicolas Prat, Bijaya K. Parida, Carmen Hinojosa-Laborde, Gary W. Muniz, Robert E. Shade, Cassondra Bauer, Wilfred Delacruz, James A. Bynum, Victor A. Convertino, Andrew P. Cap, Heather F. Pidcoke, Nandu Goswami, Nandu Goswami, Nandu Goswami
Article
Hematology
Victor A. Convertino, Natalie J. Koons
Article
Hematology
Taylor E. Schlotman, Kevin S. Akers, Sylvain Cardin, Michael J. Morris, Tuan Le, Victor A. Convertino
Article
Medicine, General & Internal
Brandon M. Carius, Jason F. Naylor, Michael D. April, Andrew D. Fisher, Ian L. Hudson, Peter J. Stednick, Joseph K. Maddry, Erik K. Weitzel, Victor A. Convertino, Steve G. Schauer
Summary: The study focuses on the challenges of hemodynamic monitoring in combat casualties and proposes improvements. The investigation found that challenges in obtaining vital signs were mainly related to training and equipment, suggesting the need for better casualty monitoring systems, especially for critically injured casualties.
Article
Medicine, General & Internal
Steven G. Schauer, Jason F. Naylor, Gregory Dion, Michael D. April, Kevin K. Chung, Victor A. Convertino
Summary: The study found that for combat casualties receiving airway management, airway interventions did not significantly affect survival rates, supporting the role of airway interventions when indicated.
Meeting Abstract
Biochemistry & Molecular Biology
Victor A. Convertino
Review
Health Care Sciences & Services
Guy Avital, Eric J. Snider, David Berard, Saul J. Vega, Sofia I. Hernandez Torres, Victor A. Convertino, Jose Salinas, Emily N. Boice
Summary: Physiological closed-loop controlled systems play an important role in clinical practice, providing accurate and targeted care while reducing the workload of healthcare professionals. These systems offer standardized care management and have advantages in fluid management and administration, particularly in conditions that require precise care. Design and maturity level of controllers vary, but they have been tested and implemented in different areas, including peri-operative care, trauma, and acute burn care.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Biotechnology & Applied Microbiology
Carlos N. Bedolla, Jose M. Gonzalez, Saul J. Vega, Victor A. Convertino, Eric J. Snider
Summary: Accurately tracking vital signs is crucial for triaging patients and providing timely treatment. Compensatory mechanisms can often obscure the patient's condition, making it difficult to assess the severity of injuries. Compensatory reserve measurement (CRM) is a triaging tool derived from an arterial waveform that allows for early detection of hemorrhagic shock. In this study, classical machine-learning models driven by specific features extracted from the arterial waveform were used to estimate CRM, resulting in similar accuracy to deep-learning algorithms. This methodology has the potential to improve trauma patient triage and enhance military and emergency medicine.
BIOENGINEERING-BASEL
(2023)
Article
Biotechnology & Applied Microbiology
Victor A. Convertino, Eric J. Snider, Sofia I. Hernandez-Torres, James P. Collier, Samantha K. Eaton, David R. Holmes III, Clifton R. Haider, Jose Salinas
Summary: This study aims to systematically evaluate the lower body negative pressure (LBNP) as a credible tool for studying human hemorrhage physiology. The evaluation based on verification and validation demonstrates the credibility, repeatability, and validity of LBNP compared to actual blood loss. The LBNP tool can be used for testing and developing advanced monitoring algorithms and evaluating wearable sensors, with the goal of improving clinical outcomes in emergency medical settings.
BIOENGINEERING-BASEL
(2023)
Review
Chemistry, Analytical
Victor A. Convertino, Steven G. Schauer, Erik K. Weitzel, Sylvain Cardin, Mark E. Stackle, Michael J. Talley, Michael N. Sawka, Omer T. Inan