Article
Plant Sciences
Darren C. J. Wong, James Perkins, Rod Peakall
Summary: Sexually deceptive plants attract specific male insects for pollination by mimicking their characteristics. This study investigated the flower color biochemistry and gene expression patterns in different groups of the sexually deceptive orchid genus Chiloglottis using chemical and transcriptome analysis. The results showed that the dark calli/callus structures in these plants have conserved biochemical basis across the genus, but there are differences in the proportion of methoxylated anthocyanin and flavonol glycoside derivatives and gene expression levels between the Reflexa/Formicifera clades and the Valida clade.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Food Science & Technology
Ming Zhao, Jiakun Fan, Qianting Liu, Hui Luo, Qingyan Tang, Chongping Li, Jurun Zhao, Xinfeng Zhang
Summary: This study investigated the phytochemicals and antioxidative activities in the flowers of Dendrobium officinale and Dendrobium devonianum. Both flowers were found to contain various amino acids, flavonoids, and fatty acids, with antioxidative capacities. These findings suggest that these edible flowers have potential for use in functional foods and pharmaceuticals.
FOOD SCIENCE & NUTRITION
(2021)
Article
Chemistry, Medicinal
Hai-Yan Zhao, Ya-Qi Wang, Yan-Cai Li, Qian Lan, Hai-Bing Liao, Heng-Shan Wang, Dong Liang
Summary: Multiple new flavonol glycosides and phenylpropanoid glycosides were isolated from Neoshirakia japonica, showing significant inhibitory effects against neuroinflammation. Compounds 1, 8, and 9 demonstrated stronger inhibitory activities compared to the positive control minocycline.
Article
Biochemistry & Molecular Biology
Aleksandra Burzacka-Hinz, Magdalena Narajczyk, Magdalena Dudek, Dariusz L. Szlachetko
Summary: Dendrobium is a species-rich genus of Paleotropical orchids, with over 1000 species, most of which are epiphytes. This study focused on the micromorphology of the labellum in 21 species of Dendrobium, revealing various types of trichomes and papillae. The presence/absence of labellum structures may not necessarily reflect phylogenetic relationships, as convergence can lead to similar structures in unrelated species.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Jinyu Li, Xinyue Zhang, Yumeng Li, Bo Liu, Rui Zhan
Summary: Eleven phenolic compounds, including two new bibenzyl-phenylpropane hybrids, were isolated from cultivated Dendrobium devonianum Paxt. Compound 1, a rare bibenzyl-phenylpropane hybrid with a coumarin core, showed potential as a natural immunosuppressive agent for T lymphocytes.
PHYTOCHEMISTRY LETTERS
(2023)
Article
Agriculture, Multidisciplinary
Qinggang Yin, Xiaoyan Han, Jingwang Chen, Zongxian Han, Liang Shen, Wei Sun, Shilin Chen
Summary: The study identified panasenoside and kaempferol 3-O-glucoside as commonly accumulated flavonol glycosides in ginseng leaves with cultivation years. A total of 50 UDP-glycosyltransferases (UGTs) were screened out to explore flavonol glycosylation in ginseng, with specific UGTs identified for the formation and modification of kaempferol 3-O-glucoside. The study highlights the significance of integrated metabolite profiles, proteomics, and phylogenetic analysis in understanding flavonol glycosylation pathways in ginseng.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Plant Sciences
Francesco Saverio Robustelli della Cuna, Jacopo Calevo, Miriam Bazzicalupo, Cristina Sottani, Elena Grignani, Stefania Preda
Summary: This study evaluated the essential oil composition of five Indian Dendrobium species, identifying different compounds present in varying concentrations in each species. The unique distribution of organic acids in certain species suggests a particular feature of these plants.
Article
Plant Sciences
Mengting Wang, Wenhui Yu, Jiapeng Yang, Zhenyu Hou, Chao Li, Zhitao Niu, Benhou Zhang, Qingyun Xue, Wei Liu, Xiaoyu Ding
Summary: Our study focuses on the Dendrobium orchids, which have large morphological divergence and difficulties in species taxonomy. We assembled the complete mitogenomes of two Dendrobium species and compared them with other orchids. The results reveal extensive variations in repetitive and chloroplast-derived sequences in Dendrobium mitogenomes, and the intergenic content has undergone expansion during evolution. We also sequenced the mitogenomes of 26 Dendrobium species and reconstructed their phylogenetic relationships based on mitochondrial and plastid data. The mitochondrial phylogeny shows partial characteristics of the plastid phylogeny and provides new insights into the phylogenetic relationships of Dendrobium species.
Article
Immunology
Xueping Wei, Wei Sun, Pengpeng Zhu, Guoteng Ou, Sheng Zhang, Yuanyuan Li, Jingjin Hu, Xuefeng Qu, Yan Zhong, Wenying Yu, Zhenqiang You, Yin Wang, Yueguo Wu
Summary: The novel polysaccharide DVP-1 from Dendrobium devonianum activates immunity through the TLR4/MyD88/NF-kappa B pathway, which enhances the ability of mice to prevent H1N1 influenza virus infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Plant Sciences
Darren C. J. Wong, James Perkins, Rod Peakall
Summary: This study investigates the chemical composition and genetic regulation of flower color patterns in Chiloglottis trapeziformis, a sexually deceptive orchid. The researchers found that flower color in this orchid is achieved through complex tissue-specific coordinated regulation of genes and biochemical pathways across multiple developmental stages.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Meng-Ting Wang, Zhen-Yu Hou, Chao Li, Jia-Peng Yang, Zhi-Tao Niu, Qing-Yun Xue, Wei Liu, Xiao-Yu Ding
Summary: The study focuses on the reconstruction of mitochondrial genomes of angiosperms with a specific focus on Dendrobium species. The findings reveal the intricate nature of the mitochondrial genomes in Dendrobium, with frequent recombinations and structural variations. The study also explores the dynamic structures of the mitochondrial genomes by quantifying gene copy numbers and DNA contents. Additionally, the study compares the phylogenetic relationships of nuclear and mitochondrial genes, discovering discordance and inferring reticulate evolution and hybridization events in Dendrobium species.
JOURNAL OF SYSTEMATICS AND EVOLUTION
(2022)
Article
Biochemistry & Molecular Biology
Haoliang Wan, Yihui Liu, Tongtong Wang, Peng Jiang, Weiwei Wen, Jiyun Nie
Summary: The downregulation of the transcription factor CsERF003 can increase the contents of major flavonoids and the precursor phenylalanine in the mutant orange and result in darker fruit color in tomato. CsERF003 may be a potentially promising gene for fruit quality improvement and engineering of natural flavonoid components.
Article
Chemistry, Medicinal
Quentin Favre-Godal, Jane Hubert, Alexis Kotland, Delphine Garnier, Camille Beaugendre, Lorene Gourguillon, Aurelie Urbain, Sonia Lordel-Madeleine, Patrick Choisy
Summary: This study combined two analytical strategies to describe the detailed composition of the hydroethanolic extract of Dendrobium fimbriatum Hook. A total of 28 metabolites were structurally elucidated, with 23 of them being reported for the first time.
NATURAL PRODUCT COMMUNICATIONS
(2022)
Article
Chemistry, Applied
Yongxiang Wang, Xue Xie, Lina Liu, Hongda Zhang, Fuyong Ni, Jianhui Wen, Yun Wu, Zhenzhong Wang, Wei Xiao
Summary: Four new flavonol glycosides were isolated from Ginkgo biloba leaves, along with nine known flavonoids and two known lignans. Their structures were determined by spectroscopic analyses, and they showed stronger cardioprotective effects compared to acylated flavonol glycosides.
NATURAL PRODUCT RESEARCH
(2021)
Article
Plant Sciences
Mark Arcebal K. Naive, Frankie Handoyo, Jeffrey Champion
Summary: A new species of orchid, Dendrobium ormerodii Handoyo, Naive & J.Champ. from Kalimantan, Borneo, is described and illustrated. It is similar to D. fulminicaule but differs in characteristics such as shorter stem and narrower leaf. The description includes detailed information on morphology, distribution, and conservation assessment.
Article
Chemistry, Applied
Wenjing Wang, Rui Zhan, Yegao Chen
NATURAL PRODUCT RESEARCH
(2020)
Article
Chemistry, Applied
Bo Liu, Ye-Gao Chen, Xing-Jun Tian, Rui Zhan
Summary: Three new diarylpropanes were isolated from the twigs and leaves of Horsfieldia kingii, along with three known compounds. Spectroscopic analysis confirmed their structures. However, bioactive evaluation showed that the new compounds were inactive in inhibiting DDC enzyme.
NATURAL PRODUCT RESEARCH
(2021)
Article
Plant Sciences
Ying Liu, Zhao Lu, Mei Wang, Yang Chen, Rui Zhan, Li-Dong Shao, Ye-Gao Chen
PHYTOCHEMISTRY LETTERS
(2020)
Article
Chemistry, Organic
Rui Zhan, Dashan Li, Yuan-Lie Liu, Xiao-Yan Xie, Lei Chen, Li-Dong Shao, Wen-Jing Wang, Ye-Gao Chen
Article
Plant Sciences
You-Xi Zhang, Zhao Lu, Wen-Chao Wu, Ye-Gao Chen, Rui Zhan
Summary: Thirteen flavonoids, including two new compounds, were isolated from the twigs and leaves of Knema elegans. Compounds 1-3, 12, and 13 showed moderate inhibitory effects against α-glycosidase, with IC50 values ranging from 11.80 to 15.77 μM. Additionally, compounds 1, 2, 4, 7, 11, and 13 exhibited radical scavenging capacities in the DPPH and APTS models.
PHYTOCHEMISTRY LETTERS
(2021)
Article
Chemistry, Organic
Mei Wang, Yuan-Lie Liu, Dashan Li, Wen-Wen Xiao, Yang Chen, Hong-Lin Zhang, Rui Zhan, Li-Dong Shao
Summary: Inspired by the oxy-tyrosinase type II copper enzyme, a biomimetic synthesis of the natural product hors-fiequinone A was achieved, showing inhibitory activity on nitric oxide production and potential anti-inflammatory effects.
TETRAHEDRON LETTERS
(2021)
Review
Chemistry, Medicinal
Mei Wang, Wei Wang, Dashan Li, Wen-Jing Wang, Rui Zhan, Li-Dong Shao
Summary: This review highlighted the significant advances in alpha-C(sp(3))-H arylations of cyclic carbonyl compounds in recent years, including methods, mechanisms, and applications, emphasizing their importance in the total synthesis of natural products.
NATURAL PRODUCTS AND BIOPROSPECTING
(2021)
Article
Biochemistry & Molecular Biology
Ying Liu, Jia-Qian Zhang, Rui Zhan, Ye-Gao Chen
Summary: Two new isopentenyl bibenzyls and 26 known phenolic compounds were isolated from the stems of cultivated Dendrobium chrysotoxum. The isolated compounds showed anti-inflammatory and anti-proliferative activities, indicating their potential in therapeutic applications.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Biochemistry & Molecular Biology
Shun-Yi Yang, Gao-Hua Jiang, Qiong-Hui Sun, Qing Luo, Chao-Xun Wang, Bo Liu, Rui Zhan, Haji Akber Aisa, Ye-gao Chen
Summary: The first phytochemical investigation of Machilus salicina Hance resulted in the isolation of thirteen compounds, including some that had never been found in the Machilus genus before. These compounds belong to various chemical classes and have significant chemotaxonomic implications.
BIOCHEMICAL SYSTEMATICS AND ECOLOGY
(2022)
Article
Chemistry, Organic
Yang Chen, Xin-Ting Hu, Xiao-Yan Xie, Dashan Li, Chun-Xia Zheng, You-Xi Zhang, Wen-Jing Wang, Rui Zhan, Li-Dong Shao
Summary: Herein, a two-step synthesis of 1-methyl-6H-indol-6-one, an N-containing 6/5 fused bicyclic building block in Amaryllidaceae alkaloids, is described. The key step involves a 'one-pot' ozonolysis/reductive amination/cyclization reaction of allylated cyclohexa-1,3-dione to yield bicyclic compounds. Furthermore, the formal total synthesis of natural product gamma-lycorane was accomplished through a photo-promoted cyclization/oxidation cascade reaction starting from the resulting bicyclic intermediate.
SYNTHESIS-STUTTGART
(2023)
Article
Biochemistry & Molecular Biology
Chao -Fan Wang, Ying Liu, Shou-Zhen Du, Ye-Gao Chen, Rui Zhan
Summary: Five compounds were isolated from Horsfieldia kingii, including a dimeric diarylpropane, a new flavane, and three spirocyclic monomers. The structures and absolute configurations of these compounds were determined through spectroscopic data and ECD calculations. Biological evaluations showed that compounds 1-3 and 5-6 exhibited immunosuppressive activities against T lymphocytes and compound 1 also showed anti-inflammatory effects.
BIOORGANIC CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Wen-Wen Xiao, Hong-Lin Zhang, Chao-Fan Wang, Yang Chen, Rui Zhan, Dashan Li, Li-Dong Shao
Summary: A new phenylpropanoid compound named myristriol (1) was isolated from the seed kernel of Myristica fragrans Houtt, along with 11 known compounds. The chemical structures were determined through extensive spectroscopic analysis. The relative configuration of compound 1 was confirmed as erythro-1 by comparing its NMR data with those of synthetic erythro- and threo-diastereoisomers.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Biochemistry & Molecular Biology
Rui Zhan, Xin-Yue Zhang, Zhi-Yuan Li, Bo Liu, Ye-Gao Chen
Summary: Two new bibenzyl-phenylpropane hybrids, dendrophenols A and B (1 and 2), along with nine known bibenzyls, were isolated from the aerial part of Dendrobium devonianum Paxt. Their structures were determined by extensive spectroscopic methods and methylation. Bioassays revealed that compounds 1-9 exhibited specific immunosuppressive effects on T lymphocytes, with IC50 values ranging from 0.41 to 9.4 μM. Compounds 1 (IC50 = 1.62 μM) and 2 (IC50 = 0.41 μM) showed promising potential as immunosuppressive agents for T lymphocytes, with selectivity indices of 19.9 and 79.5, respectively.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Plant Sciences
Jinyu Li, Xinyue Zhang, Yumeng Li, Bo Liu, Rui Zhan
Summary: Eleven phenolic compounds, including two new bibenzyl-phenylpropane hybrids, were isolated from cultivated Dendrobium devonianum Paxt. Compound 1, a rare bibenzyl-phenylpropane hybrid with a coumarin core, showed potential as a natural immunosuppressive agent for T lymphocytes.
PHYTOCHEMISTRY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Chao-Fan Wang, Fang Kuang, Wen-Jiang Wang, Lei Luo, Qiu-Xia Li, Ying Liu, Rui Zhan
Summary: Knema furfuracea is a tropical evergreen plant that belongs to the Myristicaceae family. Phytochemical investigation led to the isolation of 11 phenolic compounds, including a new flavonoid knemavane A. Compounds 1, 2, and 6 showed inhibitory activities against nitric oxide production in LPS-activated macrophages.
RESULTS IN CHEMISTRY
(2021)
