Journal
NATURAL PRODUCT RESEARCH
Volume 27, Issue 17, Pages 1532-1536Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2012.733388
Keywords
Actinosynnema pretiosum; Endophyte; Ansamitocins
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Funding
- IURA (Industry-University-Research institute Alliance) [2010ZX09401-403]
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By using various column chromatography for purification, two new compounds of ansamitocin (1 and 2) were isolated from the extracts of fermentation broth of Actinosynnema pretiosum FIM06-0063. Their structures were established as maytansinol-9-methyl ether-3-propionate (1) and maytansinol-9-methyl ether-3-3-methy-butyrate (2), respectively, by an extensive NMR analysis.
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