Journal
NATURAL PRODUCT RESEARCH
Volume 27, Issue 19, Pages 1732-1736Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2012.750318
Keywords
Cyperus rotundus L; rotunduside; iridoid glycoside; macrophages respiratory burst
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Funding
- Key Science and Technology Program of Zhanjiang City [2012C3102017]
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A new iridoid glycoside, rotunduside (1), along with four known iridoid glycosides, 10-O-p-hydroxybenzoyltheviridoside (2), 10-O-vanilloyltheviridoside (3), 6-O-(trans-p-coumaroyl)-procumbide (4) and loganic acid (5), was isolated from the rhizomes of Cyperus rotundus L. Their chemical structures were elucidated on the basis of UV, IR, MS and NMR spectroscopic analyses. In addition, the macrophages respiratory burst (MRB) inhibitory activity of the isolated compounds was reported. Compound 2 exhibited considerable MRB inhibitory activity in the test with IC50 value of approximate to 37M.
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