4.4 Article

Redox properties of Abarema cochliacarpos (Gomes) Barneby & Grime (Fabaceae) stem bark ethanol extract and fractions

Journal

NATURAL PRODUCT RESEARCH
Volume 27, Issue 16, Pages 1479-1483

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2012.722083

Keywords

Abarema cochliacarpos; redox properties; oxidative damage; superoxide dismutase; NO scavenger; TRAP/TAR

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The redox properties of the hydroethanol extract (EE) and its ethyl acetate (EAF) and hydromethanol (HMF) fractions obtained from Abarema cochliacarpos (Gomes) Barneby & Grimes stem bark were evaluated. EAF had the highest total phenol content (848.62 +/- 78.18mgg(-1)), while EE showed the highest content of catechin (71.2 mu gg(-1)). EE, EAF and HMF exhibited the highest levels of antioxidant activity at 100 and 1000 mu gmL(-1) when the non-enzymatic antioxidant potential was evaluated by the total reactive antioxidant potential, total antioxidant reactivity and nitric oxide scavenging assays. In addition, EAF and HMF showed SOD-like activity. The results for EE, EAF and HMF in this study showed that A. cochliacarpos (Gomes) Barneby & Grimes stem bark have redox properties and may be able to help the endogenous enzymatic and non-enzymatic systems to keep the redox balance.

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