Journal
NATURAL PRODUCT RESEARCH
Volume 27, Issue 17, Pages 1607-1610Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2012.740033
Keywords
Pseudocyphellaria coriifolia; depsides; triterpenes; trypanocidal activity
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Funding
- Direccion de Investigacion, Universidad de Valparaiso [CORFO 07-CT9-PDT-68]
- Direccion General de Investigacion y Postgrado (DGIP) of the Universidad Tecnica Federico Santa Maria (PIIC QUI)
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The lichen Pseudocyphellaria coriifolia is a species endemic to southern South America. From the lichen thallus, methyl evernate, tenuiorin and three hopane triterpenoids were isolated and identified as the main lichen constituents. Their trypanocidal effects were screened against epimastigotes of Trypanosoma cruzi. The results of the biological test showed that some hopane terpenoids exhibit antiparasitic properties.
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