Journal
NATURAL PRODUCT RESEARCH
Volume 26, Issue 15, Pages 1375-1380Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2011.587187
Keywords
simaroubaceae; Ailanthus altissima; neolignan glycoside; tobacco mosaic virus; anti-phytoviral
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Funding
- Ministry of Education of China [20093515120005]
- Provincial Natural Science Foundation of Fujian [2009N0016, 2009J050490]
- Department of Education of Fujian Province [JA09100]
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A new seco-neolignan glycoside, seco-dehydrodiconiferyl alcohol-4-O-beta-D-glucopyranoside (1), together with eight known compounds, were obtained from the EtOH extract of the root bark of Ailanthus altissima. Their structures were elucidated based on the spectroscopic data. Three neolignan glycosides including 7,9,9'-trihydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan-4-O-beta-D-glucopyranoside (5), sonchifolignan B (6) and citrusin B (7) exhibited moderate in vitro inhibitory effect on tobacco mosaic virus replication with I-C50 values 0.30, 0.35 and 0.26 mmol L-1, respectively.
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