Article
Biochemistry & Molecular Biology
Jackapun Kwangjai, Dania Cheaha, Rodiya Manor, Nusaib Sa-ih, Nifareeda Samerphob, Acharaporn Issuriya, Chatchai Wattanapiromsakul, Ekkasit Kumarnsit
Summary: The study explored the chemical components and effects of Citrus reticulata essential oil on brain waves and sleep patterns in rats. D-limonene was identified as the major constituent, and although the EEG patterns were similar to diazepam, differences were seen in sleep-wake analyses. Citrus EO reduced REM sleep latency and increased total time and episode numbers of REM sleep. These findings demonstrated unique CNS effects of Citrus reticulata EO with potential clinical applications.
BIOMEDICAL JOURNAL
(2021)
Article
Plant Sciences
Ippolito Camele, Daniela Grul'ova, Hazem S. Elshafie
Summary: The study evaluated the potential antimicrobial activity of peppermint essential oil against common plant pathogens, showing promising antifungal effects but only moderate antibacterial effects.
Article
Chemistry, Analytical
Mejra Bektasevic, Mladenka Jurin, Marin Roje, Olivera Politeo
Summary: Bioactive compounds from plants are important in slowing neurodegenerative diseases, such as Alzheimer's disease, by inhibiting cholinesterase enzymes. Oxidative stress is associated with the development of Alzheimer's disease. The chemical composition and biological activity of the essential oil and extracts of Teucrium montanum were studied.
Article
Engineering, Multidisciplinary
Phat T. Dao, Nhi Y. T. Tran, Quyen N. Tran, Giang L. Bach, Tan Lam
Summary: Kinetic modeling is essential in large-scale extraction processes, and in this study, different kinetic models were used to extract essential oils from pomelo peel materials. The non-linear pseudo first order model was found to best fit the experimental data, with the obtained essential oil characterized by an abundance of limonene.
ALEXANDRIA ENGINEERING JOURNAL
(2022)
Article
Food Science & Technology
Nur Cebi, Azime Erarslan
Summary: Citrus oils can be used as natural preservatives and flavorings in food products. The research found that Citrus bergamia EO has antibacterial and antifungal effects against different pathogens. These findings highlight the potential use of Citrus bergamia EO in food engineering to maintain food quality, safety, and sustainability.
Article
Biochemistry & Molecular Biology
Shaza H. Aly, Omayma A. Eldahshan, Sara T. Al-Rashood, Faizah A. Binjubair, Mahmoud A. El Hassab, Wagdy M. Eldehna, Stefano Dall'Acqua, Gokhan Zengin
Summary: The chemical compositions and potential activities of Psidium guajava (Guava tree) were investigated in this study. The results showed that the extracts and essential oil of Guava tree have potential antioxidant and enzyme inhibitory properties, suggesting their potential use in the treatment of oxidative stress, neurodegenerative diseases, and diabetes mellitus.
Article
Food Science & Technology
Wei Liu, Zehua Li, Kai Yang, Peilong Sun, Ming Cai
Summary: Finger citron essential oil (FCEO) encapsulated by nanoemulsion can improve its digestion in the colon and its effects on human gut microbiota, promoting the growth of beneficial bacteria and suppressing the growth of harmful bacteria. Therefore, FCEO may have potential applications in food preservation.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Chemistry, Applied
Marika Pellegrini, Sara Palmieri, Antonella Ricci, Annalisa Serio, Antonello Paparella, Claudio Lo Sterzo
Summary: This study found that hemp essential oil has significant antioxidant capacity and good antibacterial activity, especially against certain Gram-positive bacteria.
NATURAL PRODUCT RESEARCH
(2021)
Article
Agricultural Engineering
Seyed Ali Moetamedipoor, Mohammad Jamal Saharkhiz, Ahmad Reza Khosravi, Abolfazl Jowkar
Summary: Mentha, an important aromatic plant in the Lamiaceae family, was studied for its essential oil yield and components in different regions of Iran. Gas chromatography analysis revealed the diverse composition of its essential oils, with each species consisting of 46-64 constituents. The study identified new constituents and highlighted the importance of understanding the genetic and proteomic levels of these mint species.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Integrative & Complementary Medicine
Nausheen Nazir, Muhammad Zahoor, Faheem Uddin, Mohammad Nisar
Summary: The essential oil extracted from the fruits of Elaeagnus umbellata demonstrated reasonable antioxidant, anticholinesterase, and antidiabetic potentials, suggesting it could be a potential alternative medicine in treating diabetes and neurodegenerative disorders. However, further studies are needed to isolate responsible compounds and evaluate the observed potential in animal models.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2021)
Article
Agricultural Engineering
Hamid Ahadi, Majid Shokrpour, Reza Fatahi, Mohammad Reza Naghavi, Mohammad Hossein Mirjalili
Summary: The metabolic diversity of 24 Iranian Rosa damascena genotypes was studied, and major compounds and phytochemical markers were identified. This study provides valuable information for further commercial cultivation and production of essential oils, flavonoids, and anthocyanins.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Nutrition & Dietetics
Weixuan Tang, Zhuo Zhang, Dechao Nie, Yan Li, Shutian Liu, Yanling Li
Summary: Citrus Medica limonum essential oil (LEO) has protective effects against intestinal inflammation induced by E. coli K99. LEO pretreatment alleviates diarrhea, immune organ responses, and inflammation in mice. It maintains immunoglobulin levels, reduces inflammatory cytokine levels, and improves intestinal integrity.
Article
Food Science & Technology
Jiajing Guo, Xiao Hu, Zhipeng Gao, Gaoyang Li, Fuhua Fu, Xuebo Shang, Zengenni Liang, Yang Shan
Summary: Research showed that Fingered Citron essential oil (FCEO) has strong anti-listeria activity, causing cell morphology changes, and L. monocytogenes exhibited various cell responses in its presence. Genome-wide transcriptome analysis revealed that L. monocytogenes adapt by enhancing motility, promoting escape mechanisms, increasing energy intake, and altering metallic cation uptake in response to FCEO exposure.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Plant Sciences
Nouran M. Fahmy, Sameh S. Elhady, Douha F. Bannan, Rania T. Malatani, Haidy A. Gad
Summary: The study used a mass-based metabolomic approach to analyze the essential oil compositions of six cultivars of Citrus reticulata. The antiaging capability of the essential oils was investigated by measuring their ability to inhibit enzymes involved in aging. The results identified certain cultivars with promising potential for antiaging skincare products.
Article
Biochemistry & Molecular Biology
Marijana Popovic, Maja Jukic Spika, Maja Versic Bratincevic, Tonka Nincevic, Ana Mateskovic, Marija Mandusic, Jaksa Rosin, Marija Nazlic, Valerija Dunkic, Elda Vitanovic
Summary: Olive leaves, a by-product of olive production, were analyzed to study differences in physical and chemical properties between Croatian domestic and introduced cultivars. Essential oil volatile profiles varied significantly between cultivars, with Oblica showing unique characteristics.
Article
Chemistry, Applied
Natale Badalamenti, Maurizio Bruno, Monica R. Loizzo, Valeria Puccio, Raimondo Gaglio, Nicola Francesca, Luca Settanni, Francesco Sottile
Summary: This study characterized the chemical composition of the almond skin of Prunus dulcis L. variety Casteltermini and evaluated its inhibitory activity against pathogenic, spoilage, and useful microorganisms. The n-hexane extract of almond skin showed strong inhibition against Staphylococcus aureus growth, indicating its potential as a food bio-preservative and pharmaceutical product.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Analytical
Carlo Bergonzi, Annalisa Bianchera, Giulia Remaggi, Maria Cristina Ossiprandi, Ruggero Bettini, Lisa Elviri
Summary: The growing demand for personalized medicine requires innovative drug manufacturing using 3D printing technology to produce hydrogels for controlled drug delivery. This study explored the use of chitosan/alginate-based hydrogels loaded with silver sulfadiazine for wound healing. Different 3D chitosan/alginate architectures were designed to modulate drug release, and significant differences were observed in terms of elasticity, water content, and antimicrobial potency.
Article
Pharmacology & Pharmacy
Annalisa Bianchera, Marino Nebuloni, Nicola Colombo, Davide Pirola, Ruggero Bettini
Summary: The aim of this study is to investigate the dissolution behavior of rifaximin alpha, beta, and amorphous forms in relation to their relative thermodynamic stability. The conversion from metastable alpha and amorphous forms to stable beta form mediated by solution and moisture was elucidated. The alpha form dissolves mainly by transitioning to the beta form at relative humidity higher than 40%.
Article
Food Science & Technology
Vincenzo Sicari, Rosa Romeo, Antonio Mincione, Simone Santacaterina, Rosa Tundis, Monica Rosa Loizzo
Summary: This study investigated the phytochemical content and bioactivity of Lycium barbarum collected in Calabria and evaluated the possibility of enriching traditional ciabatta bread with goji fresh flesh puree. The enriched bread showed good levels of bioactive compounds and exhibited antioxidant and inhibitory activities against metabolic enzymes. Sensory analysis confirmed the slight modification in appearance but not in flavor and taste of the bread.
Review
Chemistry, Applied
Umile Gianfranco Spizzirri, Monica Rosa Loizzo, Francesca Aiello, Sabrina Antonia Prencipe, Donatella Restuccia
Summary: This review provides an overview of different types of non-dairy kefir products, which use fruits or vegetables as substrates for fermentation. The microbiological, chemical-physical, technological, and sensory aspects of each formulation are discussed, along with other potential health benefits.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Green & Sustainable Science & Technology
Vincenzo Sicari, Irene Maria Grazia Custureri, Rosa Tundis, Monica Rosa Loizzo
Summary: This study compared the physico-chemical characteristics and biological activity of olive mill wastewater (OMW) obtained by two different types of three-phase decanters: a traditional one and a water-saving ARA decanter. The results showed that the OMW extract obtained by the ARA decanter had a higher concentration of phenolic compounds, higher antioxidant activity, and moderate enzyme inhibitory activity, while reducing environmental impact.
Article
Pharmacology & Pharmacy
Davide D'Angelo, Eride Quarta, Stefania Glieca, Giada Varacca, Lisa Flammini, Simona Bertoni, Martina Brandolini, Vittorio Sambri, Laura Grumiro, Giulia Gatti, Giorgio Dirani, Francesca Taddei, Annalisa Bianchera, Fabio Sonvico, Ruggero Bettini, Francesca Buttini
Summary: This study developed a dry inhalation powder of cyclosporine-A for lung transplantation rejection prevention and COVID-19 treatment. The impact of excipients on the powder's critical quality attributes was investigated. The optimized powder exhibited faster dissolution, better respirability, and showed efficacy in reducing IL-6 and inhibiting SARS-CoV-2 replication, suggesting its potential as a therapeutic strategy for lung rejection prevention and COVID-19 treatment.
Article
Biochemistry & Molecular Biology
Rosa Tundis, Giuseppina Augimeri, Adele Vivacqua, Rosa Romeo, Vincenzo Sicari, Daniela Bonofiglio, Monica Rosa Loizzo
Summary: This study characterized bamboo leaf and sheath extracts, revealing their antioxidant and anti-inflammatory properties. Bamboo leaves contain phenolic compounds, while sheaths are rich in phenolic acids. These findings suggest potential applications of bamboo leaf and sheath in the nutraceutical, cosmetic, and pharmaceutical industries.
Article
Food Science & Technology
Francesco Sottile, Assunta Napolitano, Natale Badalamenti, Maurizio Bruno, Rosa Tundis, Monica Rosa Loizzo, Sonia Piacente
Summary: For the first time, a new accession of myrobalan from Sicily was studied for its chemical and nutraceutical properties. The extracts of fresh myrobalan fruits were found to contain abundant phenolic compounds and antioxidants, with potential inhibitory effects on obesity and metabolic syndrome.
Review
Plant Sciences
Rosa Tundis, Jianbo Xiao, Ana Sanches Silva, Filipa Carreiro, Monica Rosa Loizzo
Summary: Citrus is a significant genus in the Rutaceae family, known for its medicinal and economic value, and including crops such as lemons, oranges, grapefruits, and limes. Citrus species are rich in carbohydrates, vitamins, dietary fiber, and phytochemicals, with various health-promoting properties. Citrus essential oils, mainly composed of monoterpenes and sesquiterpenes, have antimicrobial, antioxidant, anti-inflammatory, and anti-cancer properties. These oils are widely used in food, cosmetics, and pharmaceutical products.
Article
Food Science & Technology
Irene Maria Grazia Custureri, Vincenzo Sicari, Monica Rosa Loizzo, Rosa Tundis, Ana Cristina Soria, Angelo Maria Giuffre
Summary: The aim of this study was to investigate the impact of two enrichment processes on the quality and bioactivity of Ottobratica extra virgin olive oil with ginger. The results showed that the addition of ginger improved the antioxidant activity and inhibitory effect on enzymes.
Review
Plant Sciences
Rosa Tundis, Jayanta Kumar Patra, Marco Bonesi, Subrata Das, Rajat Nath, Anupam Das Talukdar, Gitishree Das, Monica Rosa Loizzo
Summary: Despite advancements in treatment strategies, cancer remains a leading cause of death globally. Therefore, the main focus should be on early cancer diagnosis, optimal therapeutic strategies, and the search for more effective molecules. This review comprehensively summarizes the potential anti-cancer properties of andrographolide, highlighting its mechanisms of action, pharmacokinetics, and potential side effects, while discussing future perspectives, challenges, and limitations of use.
Article
Biochemistry & Molecular Biology
Maria Concetta Tenuta, Monica Rosa Loizzo, Rosa Tundis, Annabelle Dugay, Chouaha Bouzidi, Arul Marie, Rosaria Acquaviva, Anna Rita Cappello, Brigitte Deguin
Summary: This study analyzed extracts of Cornus sanguinea and Cornus mas fruits and compared their inhibitory effects on key enzymes and their impact on health. Flavonoids, iridoids, and phenolic acids were identified as the main healthy compounds. The extracts from Cornus sanguinea showed significant antioxidant effects and promising enzyme inhibitory activity.
Article
Biochemistry & Molecular Biology
Maria Concetta Tenuta, Monica Rosa Loizzo, Rosa Tundis, Annabelle Dugay, Chouaha Bouzidi, Arul Marie, Rosaria Acquaviva, Anna Rita Cappello, Brigitte Deguin
Summary: In this study, extracts of Cornus sanguinea and Cornus mas fruits were analyzed using different extraction methods. The results showed that these extracts exhibited significant antioxidant activity and inhibited key enzymes associated with metabolic disorders. The findings suggest the potential use of Cornus species in the development of functional foods and nutraceuticals.
