Journal
NATURAL PRODUCT RESEARCH
Volume 24, Issue 11, Pages 995-1003Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410902847302
Keywords
isolation; synthesis; flavonols; comparison; antioxidant activity
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- Quaid-i-Azam University, Islamabad, Pakistan
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Phytochemical investigation of the leaves of Astragalus beckari yielded four flavonol aglycones, namely kaempferol, quercetin, 5-deoxy kaempferol and fisitin. These isolated compounds were then synthesised in the laboratory using the Algar-Flyn-Oyamad reaction. Antioxidant activity of both the isolated and synthesised flavonoids was compared using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay method. The isolated flavonoids were found to be more active.
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