Synthetic oligosaccharides as active pharmaceutical ingredients: Lessons learned from the full synthesis of one heparin derivative on a large scale

Chemoenzymatic synthesis of glycosaminoglycans: Re-creating, re-modeling and re-designing nature's longest or most complex carbohydrate chains

(2013) P. L. DeAngelis et al.   GLYCOBIOLOGY

A Vision for Vaccines Built from Fully Synthetic Tumor-Associated Antigens: From the Laboratory to the Clinic

(2013) Rebecca M. Wilson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Use of biosynthetic enzymes in heparin and heparan sulfate synthesis

(2012) Elizabeth P. Chappell et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Toward Automated Oligosaccharide Synthesis

(2011) Che-Hsiung Hsu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering of routes to heparin and related polysaccharides

(2011) Ujjwal Bhaskar et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Specificity and selectivity profile of EP217609: a new neutralizable dual-action anticoagulant that targets thrombin and factor Xa

(2011) S. T. Olson et al.   BLOOD

Carbohydrate chemistry in drug discovery

(2011) M. Carmen Galan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chemoenzymatic Synthesis of Homogeneous Ultralow Molecular Weight Heparins

(2011) Y. Xu et al.   SCIENCE

Bioactive synthetic heparan sulfate and heparin derivatives: From long fragments mimetics to chimeras

(2010) David Bonnaffé   COMPTES RENDUS CHIMIE

Heparin/heparan sulphate-based drugs

(2010) Neha S. Gandhi et al.   DRUG DISCOVERY TODAY

Discovery and design of carbohydrate-based therapeutics

(2010) Laura Cipolla et al.   Expert Opinion on Drug Discovery

Chemoenzymatic Design of Heparan Sulfate Oligosaccharides

(2010) Renpeng Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reversibility of the anti-FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion

(2010) I. PATY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Role, Metabolism, Chemical Modifications and Applications of Hyaluronan

(2009) Nicola Volpi et al.   CURRENT MEDICINAL CHEMISTRY

Carbohydrates: A Frontier in Medicinal Chemistry

(2009) Pierre Stallforth et al.   JOURNAL OF MEDICINAL CHEMISTRY

Description of the chemical and pharmacological characteristics of a new hemisynthetic ultra-low-molecular-weight heparin, AVE5026

(2009) C. VISKOV et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Design of biologically active heparan sulfate and heparin using an enzyme-based approach

(2009) Sherket Peterson et al.   NATURAL PRODUCT REPORTS

Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

(2009) Thomas J. Boltje et al.   Nature Chemistry

From carbohydrate leads to glycomimetic drugs

(2009) Beat Ernst et al.   NATURE REVIEWS DRUG DISCOVERY

The Structure of Glycosaminoglycans and their Interactions with Proteins

(2008) Neha S. Gandhi et al.   Chemical Biology & Drug Design

Idraparinux: review of its clinical efficacy and safety for prevention and treatment of thromboembolic disorders

(2008) Paolo Prandoni et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

(2008) P. SAVI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS