Cytisine: a natural product lead for the development of drugs acting at nicotinic acetylcholine receptors

Core Modification of Cytisine: A Modular Synthesis

(2011) Christoph Hirschhäuser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Placebo-Controlled Trial of Cytisine for Smoking Cessation

(2011) Robert West et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nicotine Decreases Food Intake Through Activation of POMC Neurons

(2011) Y. S. Mineur et al.   SCIENCE

CRYSTAL STRUCTURE OF (1R,5S)-9-NITRO- 1,2,3,4,5,6-HEXAHYDRO-1,5-METHANOPYRIDO[1,2-a][1,5] DIAZOCIN-8-ONE (9-NITROCYTISINE), C11H13O3N3

(2011) ANTONIO GALDÁMEZ et al.   JOURNAL OF THE CHILEAN CHEMICAL SOCIETY

Identification of 9-fluoro substituted (−)-cytisine derivatives as ligands with high affinity for nicotinic receptors

(2010) Nicolas Houllier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pre-clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

(2010) H Rollema et al.   BRITISH JOURNAL OF PHARMACOLOGY

Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats

(2010) Juan Andrés Abin-Carriquiry et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synthesis of a cytisine/epibatidine hybrid: a radical approach

(2010) Nicolas Houllier et al.   TETRAHEDRON

Synthesis, Binding, and Modeling Studies of New Cytisine Derivatives, as Ligands for Neuronal Nicotinic Acetylcholine Receptor Subtypes

(2009) Bruno Tasso et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cytisine-Based Nicotinic Partial Agonists as Novel Antidepressant Compounds

(2009) Y. S. Mineur et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

In vivo effects of 3-iodocytisine: Pharmacological and genetic analysis of hypothermia and evaluation of chronic treatment on nicotinic binding sites

(2009) C.A. Zambrano et al.   NEUROPHARMACOLOGY

Deconstructing cytisine: The syntheses of (±)-cyfusine and (±)-cyclopropylcyfusine, fused ring analogs of cytisine

(2008) Daniel Yohannes et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Influence of the Nitrogen Substitution in Three Cytisine Derivatives as Ligands for the Neuronal nAChRs: A Structural and Theoretical Study

(2008) Gabriella Bombieri et al.   CHEMISTRY & BIODIVERSITY

In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: Implications for Parkinson's Disease

(2008) J. Andrés Abin-Carriquiry et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

First Total Synthesis of (±)-3-Hydroxy-11-norcytisine: Structure Confirmation and Biological Characterization

(2008) Daniel Yohannes et al.   ORGANIC LETTERS

Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats

(2008) Mark G. LeSage et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Long-term exposure to the new nicotinic antagonist 1,2-bisN-cytisinylethane upregulates nicotinic receptor subtypes of SH-SY5Y human neuroblastoma cells

(2005) Loredana Riganti et al.   BRITISH JOURNAL OF PHARMACOLOGY