Application of NMR methods to the study of the interaction of natural products with biomolecular receptors

2D TR-NOESY Experiments Interrogate and Rank Ligand-Receptor Interactions in Living Human Cancer Cells

(2010) Silvia Mari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interaction between double helix DNA fragments and the new antitumor agent sabarubicin, Men10755

(2010) Stefania Mazzini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

NMR spectroscopy and computational analysis of interaction between Serratia marcescens chitinase B and a dipeptide derived from natural-product cyclopentapeptide chitinase inhibitor argifin

(2010) Hiroaki Gouda et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mapping residue-specific contacts of polymyxin B with lipopolysaccharide by saturation transfer difference NMR: Insights into outer-membrane disruption and endotoxin neutralization

(2010) Anirban Bhunia et al.   BIOPOLYMERS

Molecular Recognition of Peloruside A by Microtubules. The C24 Primary Alcohol is Essential for Biological Activity

(2010) Benet Pera et al.   CHEMBIOCHEM

Ligand-Receptor Binding Affinities from Saturation Transfer Difference (STD) NMR Spectroscopy: The Binding Isotherm of STD Initial Growth Rates

(2010) Jesús Angulo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Lectin-Based Drug Design: Combined Strategy to Identify Lead Compounds using STD NMR Spectroscopy, Solid-Phase Assays and Cell Binding for a Plant Toxin Model

(2010) João P. Ribeiro et al.   ChemMedChem

Complexity in Influenza Virus Targeted Drug Design: Interaction with Human Sialidases

(2010) Leonard M. G. Chavas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

(2010) Ashley Jarvis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multi-Timescale Dynamics Study of FKBP12 Along the Rapamycin–mTOR Binding Coordinate

(2010) Paul J. Sapienza et al.   JOURNAL OF MOLECULAR BIOLOGY

Presentation of Membrane-Anchored Glycosphingolipids Determined from Molecular Dynamics Simulations and NMR Paramagnetic Relaxation Rate Enhancement

(2010) Mari L. DeMarco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The proteasome antechamber maintains substrates in an unfolded state

(2010) Amy M. Ruschak et al.   NATURE

Mapping the Interactions between a Major Pollen Allergen and Human IgE Antibodies

(2010) Guilherme Razzera et al.   STRUCTURE

Functional Cell-Based Screening and Saturation Transfer Double-Difference NMR Have Identified Haplosamate A as a Cannabinoid Receptor Agonist

(2009) Alban Pereira et al.   ACS Chemical Biology

The carbohydrate-binding domain on galectin-1 is more extensive for a complex glycan than for simple saccharides: implications for galectin–glycan interactions at the cell surface

(2009) Michelle C. Miller et al.   BIOCHEMICAL JOURNAL

High Resolution NMR-based Model for the Structure of a scFv-IL-1β Complex

(2009) Ian C. Wilkinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NMR Structure of Pardaxin, a Pore-forming Antimicrobial Peptide, in Lipopolysaccharide Micelles

(2009) Anirban Bhunia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Artemisinin and Curcumin Micellar Formulations: Drug Solubility Studies by NMR Spectroscopy

(2009) Silvia Lapenna et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Screening Potential Antitumor Agents from Natural Plant Extracts by G-Quadruplex Recognition and NMR Methods

(2008) Qiuju Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Bound Conformation of Microtubule-Stabilizing Agents: NMR Insights into the Bioactive 3D Structure of Discodermolide and Dictyostatin

(2008) Angeles Canales et al.   CHEMISTRY-A EUROPEAN JOURNAL

Four Generations of Water-Soluble Dendrimers with 9 to 243 Benzoate Tethers: Synthesis and Dendritic Effects on Their Ion Pairing with Acetylcholine, Benzyltriethylammonium, and Dopamine in Water

(2008) Elodie Boisselier et al.   CHEMISTRY-A EUROPEAN JOURNAL

Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor

(2008) Haina Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NMR-Based Analysis of Aminoglycoside Recognition by the Resistance Enzyme ANT(4′): The Pattern of OH/NH3+Substitution Determines the Preferred Antibiotic Binding Mode and Is Critical for Drug Inactivation

(2008) Julia Revuelta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY