Lysine-based surfactants in nanovesicle formulations: the role of cationic charge position and hydrophobicity inin vitrocytotoxicity and intracellular delivery

Food for thought … on alternative methods for nanoparticle safety testing

(2016) Thomas Hartung   ALTEX-Alternatives to Animal Experimentation

HPMA Copolymers as Surfactants in the Preparation of Biocompatible Nanoparticles for Biomedical Application

(2012) Annette Kelsch et al.   BIOMACROMOLECULES

New cationic nanovesicular systems containing lysine-based surfactants for topical administration: Toxicity assessment using representative skin cell lines

(2012) Daniele Rubert Nogueira et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Rational design of new product candidates: The next generation of highly deformable bilayer vesicles for noninvasive, targeted therapy

(2012) Gregor Cevc   JOURNAL OF CONTROLLED RELEASE

Delivery of proteins to the brain by bolaamphiphilic nano-sized vesicles

(2012) George R. Dakwar et al.   JOURNAL OF CONTROLLED RELEASE

Nanofibers: Effective Generation by Electrospinning and Their Applications

(2012) P. Ramesh Kumar et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Phospholipid Bilayer-Perturbing Properties Underlying Lysis Induced by pH-Sensitive Cationic Lysine-Based Surfactants in Biomembranes

(2012) Daniele Rubert Nogueira et al.   LANGMUIR

pH-Sensitive Surfactants from Lysine: Assessment of Their Cytotoxicity and Environmental Behavior

(2012) Aurora Colomer et al.   LANGMUIR

Functionalized Fe3O4@Au superparamagnetic nanoparticles:in vitrobioactivity

(2012) J Salado et al.   NANOTECHNOLOGY

Apoptosis induction by silica nanoparticles mediated through reactive oxygen species in human liver cell line HepG2

(2012) Javed Ahmad et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The role of counterions in the membrane-disruptive properties of pH-sensitive lysine-based surfactants

(2011) D.R. Nogueira et al.   Acta Biomaterialia

Membrane-destabilizing activity of pH-responsive cationic lysine-based surfactants: role of charge position and alkyl chain length

(2011) Daniele Rubert Nogueira et al.   AMINO ACIDS

The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer

(2011) P. Venkatesan et al.   BIOMATERIALS

Lomustine Loaded Chitosan Nanoparticles: Characterization and in-Vitro Cytotoxicity on Human Lung Cancer Cell Line L132

(2011) Archana Mehrotra et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

In Vitro Evaluation of Cellular Response Induced by Manufactured Nanoparticles

(2011) Masanori Horie et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Comparative sensitivity of tumor and non-tumor cell lines as a reliable approach for in vitro cytotoxicity screening of lysine-based surfactants with potential pharmaceutical applications

(2011) Daniele Rubert Nogueira et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Inclusion of a single-tail amino acid-based amphiphile in a lipoplex formulation: Effects on transfection efficiency and physicochemical properties

(2011) Dan Lundberg et al.   MOLECULAR MEMBRANE BIOLOGY

Amorphous silica nanoparticles do not induce cytotoxicity, cell transformation or genotoxicity in Balb/3T3 mouse fibroblasts

(2011) Chiara Uboldi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Cytotoxity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing

(2011) Eleonore Fröhlich et al.   Nanotoxicology

Surface charge-specific cytotoxicity and cellular uptake of tri-block copolymer nanoparticles

(2011) Sourav Bhattacharjee et al.   Nanotoxicology

Nanotoxicology and in vitro studies: The need of the hour

(2011) Sumit Arora et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The importance of endo-lysosomal escape with lipid nanocapsules for drug subcellular bioavailability

(2010) Archibald Paillard et al.   BIOMATERIALS

Novel pH-sensitive non-ionic surfactant vesicles: comparison between Tween 21 and Tween 20

(2010) Luisa Di Marzio et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Biocompatible surfactants from renewable hydrophiles

(2010) Ma Rosa Infante et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Uptake and trafficking of liposomes to the endoplasmic reticulum

(2010) Stephanie Pollock et al.   FASEB JOURNAL

Novel Biocompatible DNA Gel Particles

(2010) M. Carmen Morán et al.   LANGMUIR

Pullulan acetate coated magnetite nanoparticles for hyper-thermia: Preparation, characterization and in vitro experiments

(2010) Fuping Gao et al.   Nano Research

Nanomaterial cytotoxicity is composition, size, and cell type dependent

(2010) Syed K Sohaebuddin et al.   Particle and Fibre Toxicology

Assessment of cytocompatibility of surface-modified CdSe/ZnSe quantum dots for BALB/3T3 fibroblast cells

(2010) Sanjeev Kumar Mahto et al.   TOXICOLOGY IN VITRO

In vitro assessments of nanomaterial toxicity

(2009) Clinton F. Jones et al.   ADVANCED DRUG DELIVERY REVIEWS

Analytical methods to assess nanoparticle toxicity

(2009) Bryce J. Marquis et al.   ANALYST

The role of hydrophobic amino acid grafts in the enhancement of membrane-disruptive activity of pH-responsive pseudo-peptides

(2009) Rongjun Chen et al.   BIOMATERIALS

Effect of chain length on physicochemical properties and cytotoxicity of cationic vesicles composed of phosphatidylcholines and dialkyldimethylammonium bromides

(2009) Chia-Hua Liang et al.   CHEMISTRY AND PHYSICS OF LIPIDS

The influence of size, lipid composition and bilayer fluidity of cationic liposomes on the transfection efficiency of nanolipoplexes

(2009) Mohammad Ramezani et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Hyaluronic acid coated poly(butyl cyanoacrylate) nanoparticles as anticancer drug carriers

(2009) Miao He et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Interactions of aluminum nanoparticles with human epidermal keratinocytes

(2009) Nancy A. Monteiro-Riviere et al.   JOURNAL OF APPLIED TOXICOLOGY

Cationic–anionic vesicle templating from fluorocarbon/fluorocarbon and hydrocarbon/fluorocarbon surfactants

(2009) Vivian A. Ojogun et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism

(2009) Wei Bai et al.   JOURNAL OF NANOPARTICLE RESEARCH

A Novel Docetaxel-Loaded Poly (ε-Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment

(2009) Lin Mei et al.   Nanoscale Research Letters

Eco-, geno- and human toxicology of bio-active nanoparticles for biomedical applications

(2009) Johan Robbens et al.   TOXICOLOGY

Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells

(2008) P. V. AshaRani et al.   ACS Nano

Cationic surfactants from lysine: Synthesis, micellization and biological evaluation

(2008) Lourdes Pérez et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition

(2008) Hui Yang et al.   JOURNAL OF APPLIED TOXICOLOGY

Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line

(2008) N.A. Monteiro-Riviere et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells

(2008) Yi-Hong Hsin et al.   TOXICOLOGY LETTERS