Article
Materials Science, Multidisciplinary
Lanqing Liang, Boxin Wei, Mengmeng Zhang, Wenbin Fang, Lei Chen, Yujin Wang
Summary: Novel TiC-based ceramics were prepared by reactive hot-pressing using TiC, Si, and ZrC powders. The microstructure and mechanical properties of the ceramics were found to be influenced by the addition of ZrC and temperature. The main toughening mechanisms observed were crack bridging by the layered Ti3SiC2 and crack deflection by the ZrSi particle. TiC-36 mol% Si-10 mol% ZrC exhibited excellent mechanical properties, surpassing most TiC-based ceramics in previous reports.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Materials Science, Ceramics
Hao-Yang Wu, Ji Zou, Mirva Eriksson, Jing-Jing Liu, Wei-Min Wang, Zheng-Yi Fu
Summary: A novel approach to rapidly densify ceramic matrix composite was developed by combining ceramic and composite processing through spark plasma sintering. The newly formed particles from the conversion of ZrSi2 and resin were preferentially incorporated into the preform layer with randomly oriented fibers, enhancing the overall properties of the composites.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2021)
Article
Materials Science, Ceramics
Hong-Yang Wang, Yu Li, Shu-Qiang Jiao, Guo-Hua Zhang
Summary: It is found that CaCl2 can be dissolved in silicate glasses, suggesting that using CaCl2-bearing glass for the preparation of glass-ceramic could be a potential method for treating CaCl2-bearing wastes.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2023)
Article
Materials Science, Ceramics
Shoulei Yang, Yinxiao Zhu, Lei Fan, Sirui Yang, Mengwen Zhang, Linan An
Summary: Oscillatory pressure can effectively promote densification and mechanical properties of SiCw-Al2O3-YAG ceramic composites. Samples prepared by HOP exhibit higher hardness and fracture toughness.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Ceramics
Lingappa Rangaraj
Summary: Ti3AlC2 ceramic was prepared by reactive hot pressing, exhibiting high relative density and mechanical properties. Pressure and time had a certain influence on the phase volume and density of the material at 1300 degrees C.
INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
(2023)
Article
Materials Science, Ceramics
Xin Zhang, Jia-Yu Hu, Bai-Xin Dong, Xin Li, Shu-Qing Kou, Shuang Zhang, Feng Qiu
Summary: The addition of Zn and Cu in TiB2/Al composites greatly enhanced the interfacial bonding strength and reaction temperature, leading to improved mechanical properties such as increased yield strength and ultimate compressive strength. These improvements can be attributed to solid solution strengthening and second phase strengthening.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Ceramics
Rajaguru Kannan, Lingappa Rangaraj, Vikram Jayaram
Summary: The study demonstrates that densification and reaction in non-stoichiometric TiC0.5 ceramic can be improved by adding a small amount of Ni, resulting in full density at lower pressure and comparable hardness. The enhanced relative density and residual metallic phase in the nickel-containing TiC0.5 ceramic show high flexural strength, similar to materials processed at high temperature and pressure.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2021)
Article
Materials Science, Ceramics
M. Tavakoli, B. Movahedi, A. Alhaji
Summary: Magnesium fluoride (MgF2) nanoparticles were successfully synthesized through the fluoridation method, and the influences of parameters such as pH, concentration ratio, F:Mg mole ratio, washing method, and calcination temperature were investigated. The results showed that the morphology of MgF2 nanoparticles changed from rod to spherical shape as the pH value increased from 1 to 9.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Ceramics
Hao Li, Yiping Yu, Bing Fang, Peng Xiao, Song Wang
Summary: In this study, the Hf6Ta2O17/Ta2O5 eutectic system was prepared for the first time using a combination of solvothermal method and spark plasma sintering. The eutectic liquid phase produced during the sintering process enhanced the sintering process and resulted in coherent interfaces between orthorhombic-Hf6Ta2O17 and tetragonal-Ta2O5. The clean and flat interfaces exhibited single crystal characteristics without impurities and amorphous phase, and the potential application of the eutectic system was analyzed based on microstructure analysis.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Ceramics
Jianmin Li, Buhao Zhang, Run Tian, Xiaojian Mao, Jian Zhang, Shiwei Wang
Summary: In this study, highly transparent AlON ceramics were successfully fabricated using a method involving the dissolution of gas inclusions. The optimization of fabrication parameters was conducted, resulting in the ability to anneal the ceramics without degrading their microstructure and transparency. This transformation and dissolution of gas into AlON ceramics enable the retention of high transparency and minimize loss during annealing processes.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2021)
Article
Materials Science, Ceramics
Takahiro Kozawa
Summary: The present study focuses on the microstructural development of MnCO3 microsphere compacts through hydrothermal hot-pressing (HHP), and different microstructure changes were observed. The direct production of microstructure-controlled compacts by HHP is significant for new structural designs and enhancing the functionality of existing applications.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2022)
Article
Materials Science, Ceramics
Zuzhi Huang, Yang Yang, Haipeng Lv, Caixia Shi, Tian Li, Yihan Ling, Ting Chen, Shaorong Wang
Summary: In this study, large-area PCFCs were successfully fabricated using multilayer-tape casting and hot-pressing lamination technology. Through optimizing the sintering process, PCFCs with dense electrolyte were obtained, showing good performance and durability.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2023)
Article
Materials Science, Multidisciplinary
Jianning Wang, Wensheng Liu, Yunzhu Ma, Wentan Zhu, Baishan Chen, Lei Zhang, Kuokuo Bao, Chaoping Liang, Qingshan Cai
Summary: This study systematically examines the material evolution during liquid phase sintering (LPS) process in the hot isostatic pressing process (HIP) and proposes a new strategy for designing and fabricating powder metallurgy materials.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Materials Science, Ceramics
Yong Hou, Guo-Hua Zhang, Kuo-Chih Chou
Summary: The influences of different alkali metal oxides on the crystallization behavior and densification of glass ceramics were studied. Higher sintering temperatures promoted crystalline phase precipitation and transformation. Fully dense ceramics containing Na2O could be obtained through hot pressing, while those containing K2O had lower densification levels.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2021)
Article
Chemistry, Physical
Yingchao Guo, Yongfeng Liang, Junpin Lin
Summary: In this study, the induction hot-pressing sintering method was used to synthesize Ti-47.7Al-7.1Nb-(V, Cr)+ xY2O3 (x = 0.05, 0.1, and 0.2 at%) composites, and the influence of Y2O3 content and sintering parameters on phase composition, microstructure evolution, and mechanical properties was investigated. The results showed that the addition of 0.05 at% nano-Y2O3 significantly refined the lamellar colonies and improved both the room-temperature and high-temperature mechanical properties.
Article
Anatomy & Morphology
Carla Ferreira-Baptista, Andre Queiros, Rita Ferreira, Maria Helena Fernandes, Pedro Sousa Gomes, Bruno Colaco
Summary: This study compared the functional activity and osteogenic potential of adipose tissue-derived stromal cells (ADSCs) isolated from subcutaneous and visceral adipose tissue in cats. The results showed that visceral adipose tissue had a greater osteogenic-inductive capacity, especially when retinoic acid was used.
JOURNAL OF ANATOMY
(2023)
Article
Materials Science, Multidisciplinary
Tania Peixoto, Daniel Silva, Miguel Rodrigues, Miguel Neto, Rui Silva, Maria C. Paiva, Liliana Grenho, Maria Helena Fernandes, Maria A. Lopes
Summary: This study investigates the surface functionalization of polymeric braids to improve their application in tendon repair. By incorporating amine groups, the researchers successfully enhance the interaction between cells and the material, potentially improving the biointegration of the braids. The NH3 plasma approach is considered more environmentally friendly, faster, and easier to scale-up.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2023)
Article
Chemistry, Physical
Gabriel Kato, Pedro Sousa Gomes, Karin Hermana Neppelenbroek, Claudia Rodrigues, Maria Helena Fernandes, Liliana Grenho
Summary: Calcium silicate-based cements (CSCs) are commonly used in vital pulp-capping procedures. Reduced set time and pre-mixed formulations are important during the treatment of pulpal exposure to improve work efficiency and asepsis control. The biological performance of these materials is crucial for clinical success. In this study, three fast-setting CSCs (Biodentine, TotalFill BC RRM Fast Putty, and Theracal LC) were characterized for antibacterial, irritation, and cytocompatibility features. The results showed that all three cements exhibited similar antibiofilm activity against S. mutans. The eluates of the set cements were not irritating, but elicited different cytotoxicity profiles on fibroblastic cells, with Biodentine being non-toxic, TotalFill showing dose-dependent initial toxicity, and Theracal LC being harmful at high concentrations. Compared to ProRoot MTA cement, Biodentine had a similar performance, while TotalFill and Theracal LC had poorer antibiofilm activity/cytocompatibility features, and Theracal LC raised safety concerns.
Article
Chemistry, Multidisciplinary
Edoardo Cianflone, Fabien Brouillet, David Grossin, Jeremy Soulie, Claudie Josse, Sanjana Vig, Maria Helena Fernandes, Christophe Tenailleau, Benjamin Duployer, Carole Thouron, Christophe Drouet
Summary: Biomimetic apatites have high reactivity and can be modulated by ion substitutions for in vivo response. A novel approach was developed to combine bioactive ions in a spatially controlled manner for subsequent releases. The concept was validated by developing core-shell particles with antibacterial ions in the outer shell and pro-angiogenic or osteogenic ions in the inner core.
Article
Endocrinology & Metabolism
Victor Martin, Liliana Grenho, Maria H. Fernandes, Pedro S. Gomes
Summary: This study assessed the response of human bone marrow-derived mesenchymal stromal cells to sarecycline, showing increased metabolic activity, enhanced osteoblastic differentiation, and modulation of Wnt, Hedgehog, and Notch signaling pathways. An ex vivo model also demonstrated increased collagen deposition, extended migration areas of osteogenesis, and increased bone mineral content, suggesting the potential of sarecycline for bone healing/regeneration enhancement.
JOURNAL OF BONE AND MINERAL METABOLISM
(2023)
Article
Medicine, General & Internal
Wladimir Gushiken de Campos, Rita Araujo, Victor Martin, Marilia Trierveiler, Pedro Gomes, Celso Augusto Lemos
Summary: This article presents a case of a 29-year-old male patient with glandular odontogenic cyst (GOC). The clinical manifestations and treatment methods of GOC are described. A conservative treatment approach was taken, and there was no recurrence after surgery.
Article
Environmental Sciences
Alyne Lamy-Mendes, David Lopes, Ana V. Girao, Rui F. Silva, Wim J. Malfait, Luisa Duraes
Summary: This research explores the effect of amino functionalization and the addition of carbon nanostructures to MTMS-based silica aerogels on their removal capacities for various contaminants. The aerogels successfully removed various organic compounds and drugs, achieving high adsorption capacities for toluene and xylene. The addition of a co-precursor containing amine groups and/or carbon nanomaterials enhanced the adsorption capacities of the aerogels and demonstrated their potential as alternative industrial sorbents.
Article
Engineering, Biomedical
Joana Fontes, Victor Zacharias Martin, Marta Resende, Bruno Colaco, Pedro de Sousa Gomes, Jose Manuel Amarante
Summary: This study investigated the stability of orthodontic mini-implants under immediate orthodontic functional load, with or without splinting, and examined the histomorphometric parameters of the adjacent bone tissue in an in vivo experimental model. Mini-implants were placed in rabbits' proximal tibia and loaded with a 150g force. The study found that splinting reduced the tipping of mini-implants to levels similar to unloaded implants, and immediate loading increased bone formation at the peri-implant region. This study highlights the importance of splinting in minimizing displacement while promoting bone formation in orthodontic treatment with mini-implants.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Engineering, Biomedical
Gabriel Kato, Rita Araujo, Claudia Rodrigues, Pedro Sousa Gomes, Liliana Grenho, Maria Helena Fernandes
Summary: This study aimed to evaluate the biological response of calcium silicate-based cements with distinct properties in an ex vivo model of bone development. The results showed that Biodentine (TM) exhibited the best performance among the cements tested.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Lorena Castro Mariano, Liliana Grenho, Maria Helena Fernandes, Pedro de Sousa Gomes
Summary: Osteomyelitis is a bone disease characterized by infection and tissue destruction. This study successfully established a new ex vivo bone infection model using embryonic chicken femurs colonized with Staphylococcus aureus, demonstrating the model's responsiveness at various levels of analysis.
Article
Dentistry, Oral Surgery & Medicine
Gilberto Ribeiro, Victor Martin, Claudia Rodrigues, Pedro Gomes
Summary: This ex vivo study compared the performance of WaveOne Gold (WOG), TruNatomy (TN), and ProTaper Ultimate (PU) file systems in terms of canal shaping, dentin preservation, and smear layer removal ability. The results showed that TN and PU systems had better performance in canal shaping and dentin preservation, but none of the assessed systems provided complete removal of the smear layer in the apical region.
JOURNAL OF ENDODONTICS
(2023)
Article
Cell Biology
Victor Martin, Ana Francisca Bettencourt, Catarina Santos, Maria Helena Fernandes, Pedro Sousa Gomes
Summary: This study compares the osteogenic potential of four broad-spectrum antibiotics in human bone cells and finds that these antibiotics can promote osteogenic differentiation through distinct signaling pathways, making them promising candidates for treating bone-related disorders.
Review
Pharmacology & Pharmacy
Celia Marques, Maria Helena Fernandes, Sofia A. Costa Lima
Summary: Berberine, an alkaloid extracted from plants, has shown potential as an anti-inflammatory and antioxidant agent. However, its poor solubility, low bioavailability, permeability, and absorption hinder its therapeutic efficacy. Nanotechnology has been used to improve these limitations and enhance the potential of berberine as a photosensitizer for photodynamic therapy.
Article
Dentistry, Oral Surgery & Medicine
Alexandra Vinagre, Catarina Barros, Joana Goncalves, Ana Messias, Filipe Oliveira, Joao Ramos
Summary: This study evaluated the effect of two finishing and polishing methods on the surface roughness of different resin composites. The results showed that both the polishing methods and the type of resin composite had a significant impact on the surface roughness, with differences observed between the two polishing methods. Some resin composites exhibited better polishability, while others showed inconsistent results.
INTERNATIONAL JOURNAL OF DENTISTRY
(2023)
