Article
Biochemical Research Methods
Olga A. Goryacheva, K. David Wegner, Aleksandr M. Sobolev, Ines Haeusler, Nikolai Gaponik, Irina Y. Goryacheva, Ute Resch-Genger
Summary: Light-emitting nanoparticles, known as quantum dots (QDs), have great potential for biosensing and bioimaging applications. However, their use in biological systems requires them to be water-dispersible without affecting their optical properties. In this study, researchers developed a new surface silanization method to preserve the optical properties of QDs and successfully prepared water-dispersible QDs.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Chong Li, Qi Liu, Shengyang Tao
Summary: This study reports the synthesis of a hybrid dye system based on TPE encapsulated organic dyes, achieving an ideal light-harvesting system at a low cost. The composite dye nanoparticles, synthesized through supramolecular self-assembly, exhibit co-emission of aggregation-induced emission dyes and aggregation-caused quenching dyes. Numerical simulations and molecular spectroscopy reveal the synthesis mechanism of the composite dye nanoparticles. The system demonstrates efficient cascade Forster resonance energy transfer and achieves the desired light-harvesting system.
NATURE COMMUNICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Shuling Zhou, Bin Xie, Xuan Yang, Xinfeng Zhang, Xiaobing Luo
Summary: This study successfully prepared a superior hydrophobic methylated silica-coated quantum dot material, improving its water stability. Compared to traditional materials, this new material has a longer working lifespan and greater potential for diverse applications in humid environments.
Article
Nanoscience & Nanotechnology
Gerardo Saavedra Rodriguez, Raul Sanchez-Zeferino, Christian Chapa, Mario Enrique Alvarez Ramos
Summary: In this study, the tunability of ZnS quantum dots embedded in a silica matrix from blue to cold white light emission was achieved through simple heating treatments without the need for rare earth or heavy metal ion doping. The composition of the samples changed gradually as a result of the heating, leading to alterations in their optical properties. The thermal treatment not only allowed for easy tuning of the emission color, but also increased the stability of the samples for long-term use as emitting devices.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Physical
Dhritiman Banerjee, Asit Kumar Kar
Summary: This research reports a new strategy for achieving high carrier recombination and high photocatalytic efficiency simultaneously by incorporating interface states in ZnO quantum dots. SiO2 encapsulated ZnO quantum dots (ZnO@SiO2 QDs) were prepared using TEOS and zinc acetate as precursors. The formation of interface states due to Zn-O-Si bonds between the SiO2 matrix and ZnO quantum dots was confirmed by XPS, FTIR, and negative photoconductivity tests. ZnO@SiO2 QDs exhibited remarkable photocatalytic dye degradation properties, outperforming uncoated and commercially available ZnO, with a high quantum yield ranging from 46.1% to 56.4%.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Chemistry, Physical
Sudhakar Narra, Sumit S. Bhosale, Aparna K. Kharade, Sue-min Chang, Eric Wei-Guang Diau
Summary: Femtosecond transient absorption spectral investigations were conducted to understand carrier relaxation mechanism in perovskite nanocrystals. The study found that Cs(1-x)FA(x)PbBr(3) (CF) samples exhibited slower charge recombination rates compared to CsPbBr3 (CS) samples, consistent with their photocatalytic performances.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Biochemistry & Molecular Biology
Ilia Litvinov, Anna Salova, Nikolay Aksenov, Elena Kornilova, Tatiana Belyaeva
Summary: In this study, the photophysical characteristics of core/shell InP/ZnS quantum dots (InP-QDs) were analyzed in cell culture medium, salt solutions, and directly in the cells. It was found that InP-QDs were internalized into endolysosomes in HeLa and A549 cells with similar dynamics to Cd-based QDs, but the two cell lines accumulated them differently. InP-QDs were reliably detected in the endosomes despite their low quantum yields. Factors such as cell culture medium, acidic pH, and salt solutions were found to affect the photoluminescence lifetime of InP-QDs. The scatter between endosomes in the same cell was observed, indicating the complex impact of these factors on the state of InP-QDs. The toxicity of InP-QDs for both cell lines at concentrations higher than 20 nM was demonstrated.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Materials Science, Multidisciplinary
Navneet Chaudhary, Damini Verma, Jai Gopal Sharma, Pratima R. Solanki
Summary: A novel bioinspired and fluorescent carbon quantum dots were successfully prepared from tejpata leaves extract using a simple hydrothermal method in this study. The developed fluorescent sensor showed excellent detection ability for ciprofloxacin with a high quantum yield of 31%.
Article
Materials Science, Multidisciplinary
Shuo Song, Wenzhi Wang, Bingqiang Cao
Summary: In this study, mono-dispersed pure CsPbBr3 PQDs with cubic morphologies were prepared using a modified hot-injection method. A surface activation strategy was developed to prepare single CsPbBr3@SiO2 core-shell PQDs, which exhibited improved stability compared to CsPbBr3 PQDs. The findings provide a simple and reliable synthesis method for single core-shell particles.
Review
Chemistry, Multidisciplinary
Thomas C. Wareing, Piergiorgio Gentile, Anh N. Phan
Summary: Carbon dots are regarded as a solution to the challenges faced by semiconductor quantum dots due to their high biocompatibility and ability to be synthesized from abundant and non-toxic biomass materials. In the biomedical field, biomass-based carbon dots hold great potential for research, especially in terms of synthesis and application, showing promising future development prospects.
Article
Chemistry, Multidisciplinary
Chao-Sheng Chen, Aaron Shinnosuke Yokokawa, Kuan-Hsun Tseng, Ming-Hsu Wang, Kevin Sheng-Kai Ma, Chin-Feng Wan
Summary: A simple and environmentally friendly method has been developed to prepare water-soluble fluorescent carbon dots (C-dots) for detecting reactive oxygen species (ROS). The C-dots, created using lactose as the carbon source and Tris as the passivation reagent, exhibit high fluorescence and excellent biocompatibility. They can serve as probes for fluorescence turn-off detection, with a high sensitivity to the hydroxyl radical, and can also track glucose concentrations when combined with glucose oxidase.
Article
Oncology
Heba ElSayed ElZorkany, Khaled Yehia Farroh, Haidan M. El-Shorbagy, Hisham A. Elshoky, Tareq Youssef, Taher A. Salaheldin, Salwa Sabet
Summary: This study mainly compares the efficiency and uptake of graphene quantum dots (GQDs) and cadmium-based quantum dots (Cd-QDs) for fluorescent imaging purposes in living cells. The effect of growing a silica shell on the emission and uptake of the quantum dots is also studied.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2022)
Article
Physics, Multidisciplinary
Roshan Singh, Jobin Jose
Summary: Atoms trapped in the fullerene C(60) shell, referred to as confined atoms (A @C-60), have unique features and are suitable for various applications in science and technology. A simple potential model, such as the annular square well (ASW) potential with the atom trapped in the center, adequately describes the system. However, the confined atoms can move inside the C-60, leading to the atom being off-centered. This study uses Feynman's path integral approach to break the symmetry and investigate the effect of confinement on off-centered endohedral and exohedral complexes, studying the electronic properties and the influence of varying atom location and ASW potential strength on the system.
EUROPEAN PHYSICAL JOURNAL PLUS
(2023)
Article
Nanoscience & Nanotechnology
Na Wu, Yue Zhai, Peng Chang, Hang Mei, Ziyan Wang, Hong Zhang, Qiangqiang Zhu, Pei Liang, Le Wang
Summary: The doping characteristics of Mn2+ ions in CsPbCl3 PQDs are regulated by adopting the Rb+ ions co-doping strategy, and the synthesized CsPbCl3:(Rb+, Mn2+) PQDs exhibit enhanced photoluminescence quantum yield. White light emission of CsPb(Cl/Br)(3):(Rb+, Mn2+) PQDs is achieved through anion exchange reaction, and the constructed WLED has a CIE coordinate of (0.33, 0.29) and a correlated color temperature of 5497 K.
Article
Multidisciplinary Sciences
Sophia F. Mersmann, Emma Johns, Tracer Yong, Will A. McEwan, Leo C. James, Edward A. K. Cohen, Joe Grove
Summary: This study presents a novel method that combines fluorescence microscopy and statistical modelling to accurately determine the number of molecules within a complex. By differentially labelling biomolecules and mixing them, the frequency of label appearance can be used to infer molecular counts. This approach was validated using complexes of Adenovirus particles and monoclonal antibodies.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Analytical
Jiani Yu, Weitao Yang, Shige Xing, Jun Wang, Huanxing Han, Pengfei Zhang, Chenyang Xiang, Bingbo Zhang
Article
Chemistry, Multidisciplinary
Peiru Wang, Weitao Yang, Shuzhan Shen, Chao Wu, Long Wen, Qian Cheng, Bingbo Zhang, Xiuli Wang
Article
Nanoscience & Nanotechnology
Defan Yao, Yanshu Wang, Rongfeng Zou, Kexin Bian, Pei Liu, Shuzhan Shen, Weitao Yang, Bingbo Zhang, Dengbin Wang
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Engineering, Biomedical
Weiwei Zeng, Yan Xu, Weitao Yang, Kai Liu, Kexin Bian, Bingbo Zhang
ADVANCED HEALTHCARE MATERIALS
(2020)
Review
Engineering, Biomedical
Yan Xu, Weitao Yang, Bingbo Zhang
Summary: Optical imaging is a useful tool for visualizing biological processes and disease progression, but its image quality is often compromised by background signals. To address this issue, low-background optical imaging techniques such as chemiluminescence imaging, afterglow imaging, and photoacoustic imaging have been developed. Stimuli-responsive probes, particularly those sensitive to reactive oxygen species, offer promise for improving imaging quality by reducing interference signals.
BIOMEDICAL MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Hui Wang, Weitao Yang, Kexin Bian, Weiwei Zeng, Xiao Jin, Ruizhuo Ouyang, Yan Xu, Chenyu Dai, Shuang Zhou, Bingbo Zhang
Summary: This research reports that oxygen-deficient black BiOCl nanoplates, treated with UV excitation, can generate stronger singlet oxygen under ultrasound stimulation. Furthermore, incorporating the GSH biosynthesis inhibitor BSO into BiOCl NPs resulted in enhanced ROS production, especially in the presence of overexpressed GSH in tumors. The findings highlight the potential of using this multifunctional approach for improving sonodynamic therapy in cancer treatment.
Article
Chemistry, Multidisciplinary
Kexin Bian, Weitao Yang, Yan Xu, Weiwei Zeng, Hui Wang, Hongying Liang, Tianming Cui, Zhuo Wang, Bingbo Zhang
Summary: This study demonstrates the importance of the reduction potential state of sonosensitizers in reactive oxygen species (ROS) generation. The reduction potential of band-edge is found to be critical, especially when aligned with the reduction of oxygen. Additionally, ultrasound-generated oxidation holes are effective in consuming overexpressed glutathione, enhancing cellular oxidative stress and inducing tumor cell death. The intrinsic fluorescence property of semiconductors provides imaging capability and guides the sonodynamic therapy (SDT) process.
Article
Chemistry, Multidisciplinary
Yan Xu, Weitao Yang, Yi Han, Kexin Bian, Weiwei Zeng, Liangwen Hao, Hui Wang, Yingsheng Cheng, Peijun Wang, Bingbo Zhang
Summary: This study presents a biomimetic strategy using albumin as a mediator for the synthesis of highly active molybdenum sulfide nanocatalysts, capable of generating singlet oxygen and superoxide anion simultaneously. These reactive oxygen species activate the ferroptosis pathway and cause efficient cancer therapy. The catalytic activity of the nanocatalysts is visualized in situ and a catalytic imaging modality for specific imaging of inflammation diseases is developed based on this biomimetic strategy.
Article
Chemistry, Multidisciplinary
Weitao Yang, Cuijun Deng, Xiudong Shi, Yan Xu, Chenyu Dai, Hui Wang, Kexin Bian, Tianming Cui, Bingbo Zhang
Summary: This study presents a structural and molecular fusion MRI nanoprobe for differential diagnosis of benign and malignant tumors. The nanoprobe enables both structural and molecular imaging of tumors, and can catalyze chemodynamic therapy within the tumor. This innovative nanoprobe strategy allows for the diagnosis of tumors from both spatial and molecular perspectives in a single-step MRI imaging, with potential applications in precision intervention.
Article
Engineering, Biomedical
Jun Wang, YanYan Wu, Kai Liu, Weitao Yang, Weiwei Zeng, Xiaolong Gao, ShiYuan Liu, Bingbo Zhang
Summary: The development of a pH/thermal dual-responsive multifunctional drug delivery system based on polydopamine-coated mesoporous silica-gold nanorods (PDA-AuNRs@MSN) could enhance therapeutic efficacy by combining chemo and photothermal therapy.
APL BIOENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Lu Yu, Aokun Liu, Bingbo Zhang, Jian Kuang, Xiaoqi Guo, Changlin Tian, Yi Lu
Summary: The EPR-based method presented in this study uses dual paramagnetically-labeled probes to detect protease activity, allowing for direct quantitative enzymatic kinetic assessment and screening of protease inhibitors.
CHEMICAL COMMUNICATIONS
(2021)
Review
Nanoscience & Nanotechnology
Xiao Jin, Weitao Yang, Yan Xu, Kexin Bian, Bingbo Zhang
Summary: MRI is a noninvasive technique with high spatial resolution, but traditional contrast agents always have poor target-to-background signal ratio. Activatable CAs with design strategies such as ion conversion, self-assembly, and disassembly significantly improve the TBR and show advantages in biomedical applications compared to conventional CAs.
Article
Chemistry, Multidisciplinary
Yan Xu, Weitao Yang, Defan Yao, Kexin Bian, Weiwei Zeng, Kai Liu, Dengbin Wang, Bingbo Zhang
Article
Materials Science, Biomaterials
Pei Liu, Weitao Yang, Lei Shi, Haiyan Zhang, Yan Xu, Peiru Wang, Guolong Zhang, Wei R. Chen, Bingbo Zhang, Xiuli Wang
JOURNAL OF MATERIALS CHEMISTRY B
(2019)
Article
Chemistry, Multidisciplinary
Defan Yao, Shuyan Yang, Yanshu Wang, Kexin Bian, Weitao Yang, Dengbin Wang, Bingbo Zhang
