Article
Nanoscience & Nanotechnology
Wenting Shao, Zidao Zeng, Alexander Star
Summary: The opioid crisis is a global public health crisis that has affected millions of people. Illicit fentanyl, a synthetic opioid, has emerged as the primary cause of overdose deaths. A highly sensitive, portable, and inexpensive biosensor is needed to quickly detect and assess the threat of fentanyl. This study presents a semiconductor-enriched single-walled carbon nanotube biosensor that can detect norfentanyl, the primary inactive metabolite of fentanyl, in urine samples with ultra-sensitivity and reliability.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Luyao Li, Xiaofeng Liu, Tongye Wei, Kemin Wang, Zijun Zhao, Juexian Cao, Yiwei Liu, Zhiyong Zhang
Summary: Carcinoembryonic antigen (CEA) is a recognized biomarker for lung cancer but its clinical value is limited due to the lack of high-sensitivity detection methods. In this study, a floating gate field-effect transistor (FET) biosensor was developed using a carbon nanotube (CNT) film and an undulating yttrium oxide (Y2O3) layer as the biosensing interface. The proposed biosensor exhibited a wide detection range (1 fg/mL to 1 ng/mL) and high sensitivity (72 ag/mL), making it promising for early lung cancer screening.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Hong Chen, Mengmeng Xiao, Jianping He, Yang Zhang, Yuqi Liang, Haiyang Liu, Zhiyong Zhang
Summary: Nanomaterial-based biosensors show promise in highly sensitive and selective detection of Alzheimer's disease blood biomarkers, overcoming challenges posed by the complex serum environment and low abundance of these biomarkers.
Review
Chemistry, Analytical
Zhongyu Li, Mengmeng Xiao, Chuanhong Jin, Zhiyong Zhang
Summary: The development of biosensors based on atomically thick carbon nanotubes (CNTs) as a channel material has the potential to revolutionize the field due to their small size, high sensitivity, label-free detection, and real-time monitoring capabilities. However, commercialization has not yet been achieved due to non-uniform and unstable device performance, difficulties in fabrication and sensor packaging, and a lack of reliable modification methods. This review article focuses on the practical applications of CNT-based biosensors in detecting ultra-low concentrations of biologically relevant molecules, highlighting the need for a robust commercial process that prioritizes product performance.
Article
Nanoscience & Nanotechnology
Wenting Shao, Michael R. Shurin, Sarah E. Wheeler, Xiaoyun He, Alexander Star
Summary: This study demonstrates the use of a high-purity semiconducting single-walled carbon nanotube field-effect transistor for rapid detection of SARS-CoV-2 antigens, displaying high sensitivity and specificity.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Mazin A. Zamzami, Gulam Rabbani, Abrar Ahmad, Ahmad A. Basalah, Wesam H. Al-Sabban, Saeyoung Nate Ahn, Hani Choudhry
Summary: A fast, easy-to-use, low-cost, and quantitative electrochemical biosensor based on CNT-FET has been developed for quick and accurate detection of SARS-CoV-2 S1 antigen in fortified saliva samples. The biosensor exhibits high sensitivity, selectivity, and can save time, making it a valuable platform for rapid detection of SARS-CoV-2 S1 antigen from patient saliva.
BIOELECTROCHEMISTRY
(2022)
Article
Engineering, Electrical & Electronic
Maryam Ghodrati, Ali Mir, Ali Farmani
Summary: Label-free monitoring of biomaterials using a DL-TCNTFET biosensor has been investigated for its sensitivity and performance. By adjusting parameters such as dielectric constant, improvements in ambipolar behavior and reduction in OFF current can be achieved, providing a new direction for label-free monitoring of biomaterials.
IEEE SENSORS JOURNAL
(2021)
Article
Nanoscience & Nanotechnology
Peng Lu, Maguang Zhu, Peixiong Zhao, Chenwei Fan, Huiping Zhu, Jiantou Gao, Can Yang, Zhengsheng Han, Bo Li, Jie Liu, Zhiyong Zhang
Summary: Recent advances in carbon nanotube-based integrated circuits have shown that they have potential in deep space exploration. The mechanism behind the displacement damage effect in semiconducting single-walled carbon nanotube field effect transistors (FETs) was investigated and it was found that trap generation in the gate dielectric, instead of damage to the carbon nanotube channel, was the dominant factor for device failure. This discovery suggests that carbon nanotube FETs have higher radiation tolerance than silicon devices and have potential for high-performance and high-robustness space applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Physical
Chin-Sheng Pang, Shu-Jen Han, Zhihong Chen
Summary: TFETs have emerged as a potential candidate to outperform conventional FETs at low voltages, with their operation mechanism overcoming the fundamental subthreshold swing limit. CNT-based TFETs show excellent performance with a minimum SS of 41 mV/dec and nearly no temperature dependence, paving a promising path for low-power electronic applications. TFET devices using CNTs with smaller bandgaps exhibit a record high BTBT current, indicating potential for high performance electronic applications.
Article
Chemistry, Physical
Lin Xu, Chenguang Qiu, Lian-mao Peng, Zhiyong Zhang
Summary: Carbon nanotube field-effect transistor (CNT FET) is considered a promising candidate for high-performance integrated circuits due to its ballistic transport and immunity to short channel effects. Researchers investigated how device geometry affects leakage current in CNT FETs, proposing a new structure that effectively suppresses off-state current through simulations. The proposed L-shaped-spacer CNT FET shows significantly reduced leakage current and excellent scalability, demonstrating potential for application in narrow-bandgap semiconductors.
Review
Biotechnology & Applied Microbiology
Bo Hu, Hao Sun, Jinpeng Tian, Jin Mo, Wantao Xie, Qiu Ming Song, Wenwei Zhang, Hui Dong
Summary: With the increasing demand for biomarker detection in wearable electronic devices, flexible biosensors have gained attention due to their high sensitivity, multifunctionality, rapid response, and low cost. Graphene field-effect transistors (GFETs) have emerged as key components for constructing biosensors because of their advantages of flexible substrates. This review provides a concise summary of design strategies for flexible GFET biosensors, highlighting notable advancements in sensing applications of biomolecules and discussing future challenges and prospects in this field.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Joydip Sengupta, Chaudhery Mustansar Hussain
Summary: An essential aspect of successful cancer diagnosis is the early identification of malignant tumors, which can greatly improve patient survival rates. Cancer biomarkers play a crucial role in determining the stage of cancer cells and evaluating treatment success. Conventional detection methods may not be suitable for rapid screening, but emerging biosensors, particularly CNT- and graphene-based transistor biosensors, show great potential due to their high sensitivity and selectivity. This review article discusses recent advances in the development of these biosensors for cancer detection.
Review
Physics, Applied
Lemeng Chao, Ying Liang, Xiao Hu, Huanhuan Shi, Ting Xia, Hong Zhang, Huiling Xia
Summary: Cancer is an incurable disease, and early detection is crucial for effective treatment. Traditional screening methods lack sensitivity, thus FET biosensors have been studied for their potential in early cancer detection. This review discusses the latest strategies and applications of FET biosensors in cancer sensing, with a focus on different cancer biomarkers.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Review
Chemistry, Physical
Qing Cao
Summary: This article examines the scaling advantages of carbon nanotubes compared to silicon, reviews the latest progress on addressing the manufacturability issues for scaled carbon-nanotube transistors, and discusses possible pathways for nanotube transistors to transition into commercial applications.
Article
Chemistry, Physical
Kemin Wang, Xiaofeng Liu, Zijun Zhao, Luyao Li, Qian Shang, Yiwei Liu, Zhiyong Zhang
Summary: This paper reports a carbon nanotube (CNT)-FET pH sensor with enhanced environmental stability by introducing HfO2 film into the gate insulator. The proposed sensor shows immunity to environmental interference and demonstrates high-performance pH sensing.
Article
Chemistry, Physical
Naoto Tanigaki, Katsuyuki Murata, Takuya Hayashi, Katsumi Kaneko
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2018)
Article
Physics, Applied
Masatoshi Maeda, Shin Iwasaki, Takafumi Kamimura, Katsuyuki Murata, Kazuhiko Matsumoto
JAPANESE JOURNAL OF APPLIED PHYSICS
(2008)
Article
Physics, Applied
Masuhiro Abe, Katsuyuki Murata, Tatsuaki Ataka, Kazuhiko Matsumoto
JOURNAL OF APPLIED PHYSICS
(2008)
Article
Physics, Applied
Masuhiro Abe, Katsuyuki Murata, Kazuhiko Matsumoto
JOURNAL OF APPLIED PHYSICS
(2010)
Article
Chemistry, Multidisciplinary
Masuhiro Abe, Kastuyuki Murata, Tatsuaki Ataka, Yasuo Ifuku, Kazuhiko Matsumoto
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
(2009)
Article
Nanoscience & Nanotechnology
Katsuyuki Murata, Tatsuaki Ataka
NANOSCIENCE AND NANOTECHNOLOGY LETTERS
(2009)
Article
Chemistry, Physical
Masuhiro Abe, Katsuyuki Murata, Atsuhiko Kojima, Yasuo Ifuku, Mitsuaki Shimizu, Tatsuaki Ataka, Kazuhiko Matsumoto
JOURNAL OF PHYSICAL CHEMISTRY C
(2007)
Letter
Chemistry, Physical
K Murata, M Yudasaka, S Iijima
Article
Chemistry, Physical
J Fan, M Yudasaka, J Miyawaki, K Ajima, K Murata, S Iijima
JOURNAL OF PHYSICAL CHEMISTRY B
(2006)
Article
Chemistry, Physical
K Murata, J Miyawaki, M Yudasaka, S Iijima, K Kaneko
Article
Chemistry, Multidisciplinary
CM Yang, H Noguchi, K Murata, M Yudasaka, A Hashimoto, S Iijima, K Kaneko
ADVANCED MATERIALS
(2005)
Letter
Chemistry, Physical
E Bekyarova, A Hashimoto, M Yudasaka, Y Hattori, K Murata, H Kanoh, D Kasuya, S Iijima, K Kaneko
JOURNAL OF PHYSICAL CHEMISTRY B
(2005)
Article
Chemistry, Multidisciplinary
K Murata, A Hashimoto, M Yudasaka, D Kasuya, K Kaneko, S Iijima
ADVANCED MATERIALS
(2004)
Article
Chemistry, Physical
E Bekyarova, K Murata, M Yudasaka, D Kasuya, S Iijima, H Tanaka, H Kahoh, K Kaneko
JOURNAL OF PHYSICAL CHEMISTRY B
(2003)
