Article
Nanoscience & Nanotechnology
Kannan Sapna, Joseph Sonia, Yoon- Bo Shim, A. B. Arun, K. Sudhakara Prasad
Summary: This article describes the development of a disposable immunosensor based on gold nanoparticle-modified paper electrodes for rapid and sensitive detection of leptospirosis in clinical samples. The sensor has a wide linear range and a low limit of detection, and demonstrates acceptable precision and stability.
ACS APPLIED NANO MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Antonio Minopoli, Emanuela Scardapane, Bartolomeo Della Ventura, Julian A. Tanner, Andreas Offenhaeusser, Dirk Mayer, Raffaele Velotta
Summary: A novel double-resonant plasmonic substrate for fluorescence amplification in a chip-based apta-immunoassay was reported. The substrate relies on the plasmon-enhanced fluorescence (PEF) effect to amplify the fluorescence signal. It can potentially be used for multiplexing applications. In a malaria apta-immunoassay, the substrate successfully detected Plasmodium falciparum lactate dehydrogenase (PfLDH) in human whole blood with high sensitivity and without complex pretreatments.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Applied
Subhasis Mahari, Akanksha Roberts, Sonu Gandhi
Summary: A novel electrochemical biosensor integrated with gold nanorods was used to explore the interaction between antibodies and Salmonella in this study, leading to the development of a method to detect Salmonella in meat and milk samples. The method has a long shelf life, good repeatability, and reproducibility, making it a potential alternative to conventional analytical approaches.
Article
Chemistry, Multidisciplinary
Xinru Huang, Shengbo Sang, Zhongyun Yuan, Qianqian Duan, Xing Guo, Hongpeng Zhang, Chun Zhao
Summary: Lysozymes in urine are important indicators for renal diseases. Current detection methods like ELISA are tedious, while newer methods are time-consuming and complex. A rapid, low-cost, and easy-to-prepare lysozyme detection method is still needed for clinical monitoring.
Article
Food Science & Technology
Lin Zhu, Xiu-Xiu Dong, Chun-Bin Gao, Zuoqi Gai, Yong-Xin He, Zhen-Jie Qian, Yingju Liu, Hong-Tao Lei, Yuan-Ming Sun, Zhen-Lin Xu
Summary: A highly sensitive and selective electrochemical immunosensor was established for the rapid screening of Rhodamine B in paprika and capsicol. Preparation of Rh B complete antigen, obtaining anti-Rh B monoclonal antibody, electrodeposition of cobalt hydroxide and gold nanoparticles, and optimization of the assembled immunosensor contributed to the successful development of the sensor. The assay showed a linear range for Rh B detection, high sensitivity, and good recovery rate, indicating its potential for practical applications.
Article
Chemistry, Analytical
Xinxia Fan, Dongmei Deng, Zichao Chen, Ji Qi, Yuanyuan Li, Baosan Han, Ke Huan, Liqiang Luo
Summary: A novel amperometric immunosensor was developed using ZnMn2O4@rGO composites to detect CEA, showing a broad linear detection range and low detection limit. The sensor demonstrated high sensitivity and specificity for monitoring CEA in clinical diagnosis, indicating its potential for use in tumor marker detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Materials Science, Multidisciplinary
J. E. Ortega-Valencia, J. Oliva-Ramirez, O. Garcia-Barradas, M. Jimenez-Fernandez, G. H. Rosas-Saito, J. E. Oseguera-Pena, D. V. Melo-Maximo
Summary: This study developed an immunosensor using quartz crystal microbalance (QCM) to detect Salmonella typhimurium, with gold nanoparticles as signal enhancers. The effect of gold nanoparticle size was explored to determine the optimal size for enhancing the detection signal.
Review
Chemistry, Analytical
Jingjing Jiang, Jili Xia, Yang Zang, Guowang Diao
Summary: Electrochemistry- and photoelectrochemistry-based biosensors have been recognized as powerful tools for trace monitoring of carcinoembryonic antigen (CEA) due to their high sensitivity, excellent selectivity, and low cost. They are classified into two main categories: immunosensors and aptasensors. This review presents recent examples and discusses signaling strategies, advanced materials, and detection modes.
Article
Chemistry, Analytical
Aihua Lyu, Yisha Wang, Hua Cui
Summary: In this study, a new mechanism for enhancing chemiluminescence (CL) was developed through the coembedding of N-(aminobutyl)-N-(ethylisoluminol) (ABEI) and Co2+ into gold nanoparticle-modified covalent-organic frameworks (COFs). The confinement of ABEI and Co2+ into Au-COF brought over 20-fold enhancement of CL intensity. This work proposes a novel enhancement mechanism for CL based on crystalline porous materials, which provides a new perspective for the development of CL-functionalized materials for biosensors and bioassays.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Lingya Ning, Yumin Bai, Zixiao Wang, Wenjun Wen, Junping Wang
Summary: A novel and rapid electro-chemiluminescence (ECL) immunosensor was successfully fabricated for ultrasensitive detection of 3-NT. The sensor utilized gold nanoparticles as the luminophore and electropolymerized polyaniline to promote the luminescence of the nanoparticles. It exhibited good analytical performance for 3-NT detection with a wide linear detection range and low detection limit, and had high recovery rate in practical sample applications.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Abdulrahman A. Almehizia, Ahmed M. Naglah, Lamees S. Alrasheed, Mashael G. Alanazi, Abdel El-Galil E. Amr, Ayman H. Kamel
Summary: A robust, reliable, and affordable paper-based analytical apparatus for potentiometric sensing has been developed for the rapid identification of cardiovascular disorders, which is particularly important for point-of-care monitoring.
Article
Spectroscopy
Ying Bao, Kexin Han, Zhifang Ding, Yue Li, Ting Li, Ming Guan, Guixin Li
Summary: Polypyrrole-luminol-AuNPs nanocomposites were prepared and utilized for a label-free electrochemiluminescence (ECL) immunosensor for detecting carbohydrate antigen 153 (CA153). The nanocomposites exhibited excellent ECL activity and good film-forming property, allowing them to be fixed on electrode surface without the need for additional film-forming materials.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Agriculture, Dairy & Animal Science
Kaiwen Feng, Ting Li, Cuizhu Ye, Xiaoyu Gao, Xianglin Yue, Shuangyan Ding, Qiuling Dong, Mingqi Yang, Ganhui Huang, Jinsheng Zhang
Summary: An electrochemical immunosensor was developed for the detection of Salmonella using a Fe3O4@graphene nanocomposite modified electrode. The Fe3O4@graphene nanocomposite exhibited excellent electrical signal due to the properties of graphene and Fe3O4, which greatly enhanced the sensitivity of the immunosensor. Gold nanoparticles were further deposited on the nanocomposite for antibody immobilization. The immunosensor showed a good linear relationship in the concentration range of Salmonella and a low limit of detection. It also demonstrated acceptable selectivity, reproducibility, and stability, offering a new approach for pathogenic bacteria detection in milk.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Chemistry, Analytical
Akanksha Roberts, Subhasis Mahari, Deepshikha Shahdeo, Sonu Gandhi
Summary: A novel immunosensor for detecting the spike protein of the coronavirus was reported, showing high sensitivity and stability under optimized conditions for detecting very low levels of the virus protein in standard buffer. This immunosensor could serve as a rapid, specific, and sensitive diagnostic tool for detecting traces of the coronavirus spike antigen in clinical samples.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Applied
Haoran Liu, Longyingzi Xie, Yiwen Wang, Yanlin Liu, Ruijie Fu, Yongliang Cui, Qiyang Zhao, Chengqiu Wang, Bining Jiao, Yue He
Summary: A portable immunosensor based on ALP-labeled and secondary antibody-modified AuNPs is proposed for sensitive detection of CBD. The enzymatic reactions and signal amplification strategy involving AuNPs enable a low detection limit of 0.37 ng/mL. Good-consistency results are obtained when using this portable method to analyze citrus fruit, canned citrus, and cabbage, demonstrating its potential for CBD monitoring in resource-poor settings.
Article
Ophthalmology
Zhongyun Yuan, Kai Zhuo, Qiang Zhang, Chun Zhao, Shengbo Sang
ACTA OPHTHALMOLOGICA
(2019)
Article
Biotechnology & Applied Microbiology
Qiang Zhang, Zhenyin Hai, Jic Wang, Aoqun Jian, Qianqian Duan, Jianlong Ji, Wcndong Zhang, Shengbo Sang
CURRENT NANOSCIENCE
(2019)
Article
Nanoscience & Nanotechnology
Sang Shengbo, Liu Lihua, Jian Aoqun, Duan Qianqian, Ji Jianlong, Zhang Qiang, Zhang Wendong
Article
Optics
Aoqun Jian, Gang Bai, Yanxia Cui, Chongguang Wei, Xin Liu, Qianwu Zhang, Shengbo Sang, Xuming Zhang
OPTICS COMMUNICATIONS
(2018)
Article
Chemistry, Analytical
Xing Guo, Shengbo Sang, Aoqun Jian, Shuang Gao, Qianqian Duan, Jianlong Ji, Qiang Zhang, Wendong Zhang
SENSORS AND ACTUATORS B-CHEMICAL
(2018)
Article
Chemistry, Physical
Xiaojing Cui, Hulin Zhang, Shengli Cao, Zhongyun Yuan, Jie Ding, Shengbo Sang
Article
Energy & Fuels
Hulin Zhang, Xiaojing Cui, Shengli Cao, Qiang Zhang, Shengbo Sang, Wendong Zhang
Article
Materials Science, Multidisciplinary
Shengli Cao, Hulin Zhang, Xiaojing Cui, Zhongyun Yuan, Jie Ding, Shengbo Sang
ADVANCED ENGINEERING MATERIALS
(2019)
Article
Biochemical Research Methods
Qianqian Duan, Mingxuan Che, Shengliang Hu, Haichao Zhao, Yi Li, Xingyi Ma, Wendong Zhang, Yixia Zhang, Shengbo Sang
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2019)
Article
Nanoscience & Nanotechnology
Yi Du, Qiang Zhang, Kai Zhuo, Jianlong Ji, Zhongyun Yuan, Chao Ji, Wendong Zhang, Shengbo Sang
MICRO & NANO LETTERS
(2019)
Article
Nanoscience & Nanotechnology
Qiang Zhang, Yi Du, Youyi Sun, Kai Zhuo, Jianlong Ji, Zhongyun Yuan, Wendong Zhang, Shengbo Sang
NANOSCALE RESEARCH LETTERS
(2019)
Article
Nanoscience & Nanotechnology
Shengbo Sang, Xing Guo, Rong Liu, Jingzhe Wang, Jinyu Guo, Yixia Zhang, Zhongyun Yuan, Wendong Zhang
NANOSCALE RESEARCH LETTERS
(2018)
Article
Chemistry, Analytical
Aoqun Jian, Huiming Li, Yixia Zhang, Qianqian Duan, Qianwu Zhang, Shengbo Sang
Article
Energy & Fuels
Xiaojing Cui, Shengli Cao, Zhongyun Yuan, Gang Xie, Jie Ding, Shengbo Sang, Hulin Zhang
Article
Pharmacology & Pharmacy
Qianqian Duan, Yuan Ma, Mingxuan Che, Boye Zhang, Yixia Zhang, Yi Li, Wendong Zhang, Shengbo Sang
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2019)
