Ultrasensitive single-nucleotide polymorphism detection using target-recycled ligation, strand displacement and enzymatic amplification

Fluorescently Cationic Conjugated Polymer as an Indicator of Ligase Chain Reaction for Sensitive and Homogeneous Detection of Single Nucleotide Polymorphism

(2012) Yongqiang Cheng et al.   ANALYTICAL CHEMISTRY

Highly Selective Detection of Single-Nucleotide Polymorphisms Using a Quartz Crystal Microbalance Biosensor Based on the Toehold-Mediated Strand Displacement Reaction

(2012) Dingzhong Wang et al.   ANALYTICAL CHEMISTRY

Using Commercially Available Personal Glucose Meters for Portable Quantification of DNA

(2012) Yu Xiang et al.   ANALYTICAL CHEMISTRY

High-Resolution Melting Analysis as a Sensitive Prescreening Diagnostic Tool to Detect KRAS, BRAF, PIK3CA, and AKT1 Mutations in Formalin-Fixed, Paraffin-Embedded Tissues

(2012) Jasmin Teresa Ney et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Highly sensitive and selective colorimetric genotyping of single-nucleotide polymorphisms based on enzyme-amplified ligation on magnetic beads

(2012) Xiaojun Chen et al.   BIOSENSORS & BIOELECTRONICS

Highly sensitive and selective chemiluminescent imaging for DNA detection by ligation-mediated rolling circle amplified synthesis of DNAzyme

(2012) Haifeng Dong et al.   BIOSENSORS & BIOELECTRONICS

KRAS mutation detection by high-resolution melting analysis significantly predicts clinical benefit of cetuximab in metastatic colorectal cancer

(2012) U Malapelle et al.   BRITISH JOURNAL OF CANCER

Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly

(2012) Ai-Xian Zheng et al.   CHEMICAL COMMUNICATIONS

Magnetic particle-based ultrasensitive biosensors for diagnostics

(2012) Yue Zhang et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Gold Nanoparticle-Enabled Real-Time Ligation Chain Reaction for Ultrasensitive Detection of DNA

(2012) Wei Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optimizing the specificity of nucleic acid hybridization

(2012) David Yu Zhang et al.   Nature Chemistry

A rule of seven in Watson-Crick base-pairing of mismatched sequences

(2012) Ibrahim I Cisse et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A universal mismatch-directed signal amplification platform for ultra-selective and sensitive DNA detection under mild isothermal conditions

(2012) Xianjin Xiao et al.   Chemical Science

Homogeneous Label-Free Genotyping of Single Nucleotide Polymorphism Using Ligation-Mediated Strand Displacement Amplification with DNAzyme-Based Chemiluminescence Detection

(2011) Hong-Qi Wang et al.   ANALYTICAL CHEMISTRY

Highly sensitive chemiluminescent point mutation detection by circular strand-displacement amplification reaction

(2011) Chao Shi et al.   BIOSENSORS & BIOELECTRONICS

Label-free visual detection of nucleic acids in biological samples with single-base mismatch detection capability

(2011) Yanling Song et al.   CHEMICAL COMMUNICATIONS

A Sequential Strand-Displacement Strategy Enables Efficient Six-Step DNA-Templated Synthesis

(2011) Yu He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multilayer enzyme-coupled magnetic nanoparticles as efficient, reusable biocatalysts and biosensors

(2011) Josep Garcia et al.   Nanoscale

Dynamic DNA nanotechnology using strand-displacement reactions

(2011) David Yu Zhang et al.   Nature Chemistry

Label-free single-molecule detection of DNA-hybridization kinetics with a carbon nanotube field-effect transistor

(2011) Sebastian Sorgenfrei et al.   Nature Nanotechnology

Thermophoretic melting curves quantify the conformation and stability of RNA and DNA

(2011) C. J. Wienken et al.   NUCLEIC ACIDS RESEARCH

Engineering DNA aptamers for novel analytical and biomedical applications

(2011) Mingxu You et al.   Chemical Science

Controlled Assembly for Well-Defined 3D Bioarchitecture Using Two Active Enzymes

(2010) Dong Chung Kim et al.   ACS Nano

Triggered Polycatenated DNA Scaffolds for DNA Sensors and Aptasensors by a Combination of Rolling Circle Amplification and DNAzyme Amplification

(2010) Sai Bi et al.   ANALYTICAL CHEMISTRY

Pyrene-Excimer Probes Based on the Hybridization Chain Reaction for the Detection of Nucleic Acids in Complex Biological Fluids

(2010) Jin Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visualizing Low-Level Point Mutations: Enzyme-like Selectivity Offered by Nanoparticle Probes

(2010) Yanbing Zu et al.   Small

Cationic Conjugated Polymers for Optical Detection of DNA Methylation, Lesions, and Single Nucleotide Polymorphisms

(2009) Xinrui Duan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Ultrasensitive and Selective Colorimetric DNA Detection by Nicking Endonuclease Assisted Nanoparticle Amplification

(2009) Wei Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold-Nanoparticle-Based Multicolor Nanobeacons for Sequence-Specific DNA Analysis

(2009) Shiping Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

COLD-PCR-Enhanced High-Resolution Melting Enables Rapid and Selective Identification of Low-Level Unknown Mutations

(2009) C. A. Milbury et al.   CLINICAL CHEMISTRY

Multiplex Single-Nucleotide Polymorphism Typing by Nanoparticle-Coupled DNA-Templated Reactions

(2009) Xuejia Xue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Profiling the selectivity of DNA ligases in an array format with mass spectrometry

(2009) Joohoon Kim et al.   NUCLEIC ACIDS RESEARCH

Unlabeled Hairpin-DNA Probe for the Detection of Single-Nucleotide Mismatches by Electrochemical Impedance Spectroscopy

(2008) Ying Wang et al.   ANALYTICAL CHEMISTRY

Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing

(2008) Jin Li et al.   NATURE MEDICINE