Journal
NANO RESEARCH
Volume 6, Issue 12, Pages 853-870Publisher
TSINGHUA UNIV PRESS
DOI: 10.1007/s12274-013-0367-x
Keywords
colloidal quantum dots; semiconductor nanocrystals; DNA; conjugation; ligand exchange; covalent bond; core/shell
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Funding
- Office of Naval Research (ONR)
- National Science Foundation (NSF)
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This perspective provides an overview of the techniques that have been developed for the conjugation of DNA to colloidal quantum dots (QDs), or semiconductor nanocrystals. Methods described include: ligand exchange at the QD surface, covalent conjugation of DNA to the QD surface ligands, and one-step DNA functionalization on core QDs or during core/shell QD synthesis in aqueous solution, with an emphasis on the most recent progress in our lab. We will also discuss emerging trends in DNA-functionalized QDs for potential applications.
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