Article
Chemistry, Multidisciplinary
Fuxian Wei, Jing Chen, Xi Zhao, Yuting Wu, Huiyao Wang, Xiaoli Chen, Zuhong Xiong
Summary: High-efficiency and low-efficiency FOLEDs are achieved through doping TBRb molecules into an energy-level matched exciplex co-host. By combining the LL-RISC process in the exciplex co-host with the HL-RISC process in TBRb, the triplet energy is fully harvested, leading to a record-high EQE of 20.4%.
Article
Nanoscience & Nanotechnology
Arthur R. J. Barreto, Graziani Candiotto, Harold J. C. Avila, Rafael S. Carvalho, Aline Magalhaes dos Santos, Mario Prosa, Emilia Benvenuti, Salvatore Moschetto, Stefano Toffanin, Rodrigo B. Capaz, Michele Muccini, Marco Cremona
Summary: Organic light-emitting transistors (OLETs) combine the advantages of organic light-emitting diodes (OLEDs) and organic field-effect transistors (OFETs) but face challenges of low charge mobility and high threshold voltage. This study demonstrates that using polyurethane films as a dielectric layer material in OLET devices can significantly reduce traps and improve device parameters. The findings provide a simple solution for low-bias device operation and overcome the limiting factors of OLETs.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Inorganic & Nuclear
Hong-Xiang Nie, Bo Zhang, Yi-Ming Liu, Mei-Hui Yu, Ze Chang
Summary: Fluorescence modulation of host-guest donor-acceptor (D-A) coordination polymer (CP) materials can be achieved through subtle structural engineering, resulting in multifarious emission properties and demonstrating great potential in achieving fluorescence modulation.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Inorganic & Nuclear
Hong-Xiang Nie, Bo Zhang, Yi-Ming Liu, Mei-Hui Yu, Ze Chang
Summary: Fluorescence modulation of host-guest donor-acceptor (D-A) coordination polymer (CP) materials can be achieved through subtle structural engineering, resulting in multifarious emission properties and demonstrating great potential for fluorescence modulation.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Physics, Applied
Yiwen Chen, Liangjian Chen, Shu Xiao, Xianfeng Qiao, Dongge Ma
Summary: Using exciplex as the host and fluorescence emitter with dopant materials has been proven to be successful in fabricating highly-efficient organic light-emitting diodes. Understanding the electroluminescence mechanisms in exciplex-based devices is crucial for optimizing device configuration. In this study, exciton dynamics in devices with exciplex as the host and red fluorescence emitter were investigated.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Kyriacos Georgiou, Rahul Jayaprakash, Andreas Othonos, David G. Lidzey
Summary: This study investigates polariton-mediated energy transfer between coupled states in strong-coupled microcavities over mesoscopic distances. By separating thin-films of two J-aggregated molecular dyes with a spacer layer up to 2 micrometers thick, strong light-matter coupling and hybridisation between excitonic transitions were identified. The process of energy transfer through polaritons was found to be enhanced compared to non-cavity control structures.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Organic
Mizhen Sun, Chenglin Ma, Mingliang Xie, Lizhi Chu, Xin Wang, Qikun Sun, Wenjun Yang, Shanfeng Xue
Summary: This study synthesized two donor-acceptor (D-A) type blue emitters and improved electron mobility by introducing the acceptor molecule DPO. The molecules exhibited high electron mobility and balanced carrier mobility, leading to a highly efficient blue OLED device.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Organic
Mizhen Sun, Chenglin Ma, Mingliang Xie, Lizhi Chu, Xin Wang, Qikun Sun, Wenjun Yang, Shanfeng Xue
Summary: In this study, two donor-acceptor (D-A) type blue emitters with bipolar transmission were synthesized, and their hybridized local and charge-transfer (HLCT) excited state was demonstrated to achieve high electron mobility. The single crystal results showed that tPPIDPO exhibited effective acceptor-acceptor π-stacking and highly ordered molecular arrangement, leading to higher electron and more balanced carrier mobilities. The non-doped blue OLED based on tPPIDPO achieved a maximum external quantum efficiency (EQEmax) of approximately 7.0%, which is among the highest reported for D-A type blue fluorescence emitters with HLCT using DPO as the acceptor. The development of a blue emitter with effective acceptor-acceptor π-stacking improves and balances carrier mobilities, resulting in higher device efficiency.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Zhennan Zhao, Yuchao Liu, Lei Hua, Shouke Yan, Zhongjie Ren
Summary: This study proposes a strategy to improve the light-emitting performance of conjugated polymers by adjusting the local electronegativity of the polymer backbone. It also demonstrates the impact of strongly electronegative atoms on the charge-transfer properties of TADF polymers, leading to a rapid reverse intersystem crossing process through vibronic coupling.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Computer Science, Interdisciplinary Applications
Leandro Benatto, Omar Mesquita, Lucimara S. Roman, Rodrigo B. Capaz, Graziani Candiotto, Marlus Koehler
Summary: Photoluminescence Quenching Simulator (PLQ-Sim) is a user-friendly software for studying the dynamics of photoexcited states at the interface between organic semiconductors. It provides important information on organic photovoltaic and photothermal devices and calculates transfer rates and quenching efficiency.
COMPUTER PHYSICS COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Chengwei Lin, Pengbo Han, Shu Xiao, Fenlan Qu, Jingwen Yao, Xianfeng Qiao, Dezhi Yang, Yanfeng Dai, Qian Sun, Dehua Hu, Anjun Qin, Yuguang Ma, Ben Zhong Tang, Dongge Ma
Summary: The study investigates the hot exciton process between high-lying triplet state and lowest excited singlet state in AIE material TPB-PAPC and demonstrates the improvement in efficiency with Forster resonance energy transfer. Doping a blue fluorescent emitter aids in inhibiting losses and achieving high EQE in blue OLEDs, both in AIE and HLCT materials, leading to efficiency breakthroughs in blue fluorescence OLEDs.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Physical
Kaito Shigemasa, Antonio Atienza-Marquez, Kaisei Inoue, Sunpil Jang, Fatima Isabella Reyna Pena, Takuto Araki, Takuma Terao, Kensaku Nagasawa, Shigenori Mitsushima
Summary: Methylcyclohexane is a desirable liquid organic hydrogen carrier produced from toluene hydrogenation. The direct toluene electro-hydrogenation technique in proton exchange membrane electrolyzers avoids heat loss.
JOURNAL OF POWER SOURCES
(2023)
Article
Engineering, Chemical
Jing Song, Bo Cheng, Yujun Wang, Jian Deng, Guangsheng Luo
Summary: In this study, an asymmetric step-T-junction was developed to enhance mass transfer by modifying the structure of the droplet formation position. The mass transfer contribution of the droplet formation stage can range from 38.1% to 48.2% for the asymmetric step-T-junction, and the mass transfer coefficient can be 27.8-64.3 times higher compared to the droplet motion stage. The mass transfer coefficient of the asymmetric step-T-junction is more than an order of magnitude higher than that of the conventional T-junction under the same residence time.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Chaoke Liu, Tengyue Li, Mizhen Sun, Mingliang Xie, Yannan Zhou, Wenjuan Feng, Qikun Sun, Shi-Tong Zhang, Shanfeng Xue, Wenjun Yang
Summary: Novel host materials PPI22PPPBO and PPI33PPPBO are designed with appropriate triplet energy levels (E-T) for phosphorescent organic light emitting diodes (PhOLEDs), leading to low turn-on voltages and high external quantum efficiency (EQE). Particularly, PPI33PPPBO demonstrates ordered face-to-face stacking, improving carrier mobility and reducing efficiency roll-offs. This study presents the first application of PBO in PhOLED host materials using a twisted connection method.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
K. H. Lee, J. Y. Lee
Summary: The development of a two-channel singlet exciton harvesting device utilizing a dual TADF mechanism significantly improved the external quantum efficiency of fluorescent OLEDs. The device consisted of two TADF materials and a green fluorophore, with one serving as the main TADF matrix and the other as an exciplex, effectively maximizing singlet exciton formation and enhancing EQE by 4.7%.
MATERIALS TODAY ENERGY
(2021)
Article
Chemistry, Multidisciplinary
Brett Yurash, Alana Dixon, Carolina Espinoza, Alexander Mikhailovsky, Sangmin Chae, Hajime Nakanotani, Chihaya Adachi, Thuc-Quyen Nguyen
Summary: Research in photon upconversion focuses on improving efficiency, performance, and reducing production costs. Studies utilizing TADF sensitizers have gained interest, and for the first time, ternary photon upconversion strategy with TADF sensitizer 4CzIPN has successfully doubled the upconversion quantum yield.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Tanguy Jousselin-Oba, Masashi Mamada, Karen Wright, Jerome Marrot, Chihaya Adachi, Abderrahim Yassar, Michel Frigoli
Summary: The synthesis and optoelectronic properties of TIPS-peri-pentacenopentacene (TIPS-PPP) were reported, showing high stability and mobility for use in organic field-effect transistors and near-infrared organic light-emitting diodes. The unique structure of TIPS-PPP with a 2D brickwall motif in crystals leads to enhanced performance in devices.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Physics, Applied
Sahar Alasvand Yazdani, Amir Mikaeili, Fatima Bencheikh, Chihaya Adachi
Summary: This study investigates the impact of excitonic and photonic losses on the performance of organic semiconductor lasers. The results show that these losses can increase the laser threshold and decrease the slope efficiency. It is also found that using thermally activated delayed fluorescence (TADF) emitters as the gain medium can significantly improve the laser performance.
JAPANESE JOURNAL OF APPLIED PHYSICS
(2022)
Article
Polymer Science
Atul Shukla, Volter Entoma, Sarah K. M. McGregor, Monirul Hasan, Masashi Mamada, Evan G. Moore, Chihaya Adachi, Shih-Chun Lo, Ebinazar B. Namdas
Summary: The roll-off of external quantum efficiency (EQE) under high current injection hampers the development of organic semiconductor laser diodes (OSLDs). While progress has been made in organic semiconductors (OSCs) emitting in the blue-green region, OSCs emitting at longer wavelengths (>600 nm) lag behind in both material development and device architectures. In this study, a host-guest system comprising a high performing polymer and an efficient small molecule laser dye is used to achieve low threshold and high EQE in organic light-emitting diodes (OLEDs) fabricated via solution processing.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Polymer Science
Nicholle R. Wallwork, Masashi Mamada, Angus B. Keto, Sarah K. M. McGregor, Atul Shukla, Chihaya Adachi, Elizabeth H. Krenske, Ebinazar B. Namdas, Shih-Chun Lo
Summary: This study reports the use of dendrimers in HF-OLEDs, which have high solubility and good external quantum efficiency. Triplet diffusion is effectively hindered by steric protection of the emitters. Further improvements can be made by adding more dendrons and increasing the generation of the dendrimer.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Masaki Tanaka, Morgan Auffray, Hajime Nakanotani, Chihaya Adachi
Summary: The authors demonstrate the active control of dipole direction in organic glassy films by utilizing physical vapour deposition, which could improve the performance of organic optoelectronic and energy-harvesting devices.
Article
Chemistry, Multidisciplinary
Takahiko Yamanaka, Hajime Nakanotani, Katsuhiro Nakamoto, Chihaya Adachi
Summary: Understanding the intrinsic carrier lifetime in disordered organic solid-state semiconductors is crucial for enhancing the performance of optoelectronic devices and photocatalysts. This study reveals an ultralong intrinsic carrier lifetime of more than one month in a disordered film of an organic semiconductor stored at room temperature without external power. The extraordinary lifetime is achieved through carrier stabilization by spontaneous orientation polarization, excited spin-triplet recycling, and blocking of recombination processes in disordered films.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Tony C. Wu, Andres Aguilar-Granda, Kazuhiro Hotta, Sahar Alasvand Yazdani, Robert Pollice, Jenya Vestfrid, Han Hao, Cyrille Lavigne, Martin Seifrid, Nicholas Angello, Fatima Bencheikh, Jason E. Hein, Martin Burke, Chihaya Adachi, Alan Aspuru-Guzik
Summary: Conventional materials discovery is time-consuming, but an automated platform has the potential to accelerate materials discovery, such as for organic lasers.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Chun Li, Henrik Schopmans, Lukas Langer, Stefan Marschner, Abhinav Chandresh, Jochen Buerck, Youichi Tsuchiya, Adachi Chihaya, Wolfgang Wenzel, Stefan Braese, Mariana Kozlowska, Lars Heinke
Summary: Researchers have successfully prepared a crystalline film based on porphyrin with chiral properties and demonstrated excellent optoelectronic performance. By assembling in a metal-organic framework film, the porphyrin core becomes twisted and chiral. The close packing and crystalline order of the porphyrin cores in the film result in outstanding optoelectronic properties. Through exciting the Soret band of porphyrin, efficient photoconduction with a high On-Off ratio is achieved. Moreover, handedness-dependent circularly-polarized-light photoconduction is obtained. The combination of assembly-induced chirality with the rich porphyrin chemistry opens up possibilities for organic materials with exceptional chiral and optoelectronic properties.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Optics
Xiao-Chun Fan, Kai Wang, Yi-Zhong Shi, Ying-Chun Cheng, Yi-Ting Lee, Jia Yu, Xian-Kai Chen, Chihaya Adachi, Xiao-Hong Zhang
Summary: Researchers have developed a new ultrapure green emitter called DBTN-2, which greatly improves the efficiency and color purity of OLED technology. The unique molecular design of this material reduces relaxation energy between excited and ground states and enhances spin-orbit couplings, resulting in highly efficient operation. These advancements make DBTN-2 a promising candidate for commercial green OLED displays.
Article
Chemistry, Multidisciplinary
Masashi Mamada, Satoshi Maedera, Susumu Oda, Thanh Ba Nguyen, Hajime Nakanotani, Takuji Hatakeyama, Chihaya Adachi
Summary: In this study, distributed feedback (DFB) laser devices were fabricated to investigate the light amplification properties of thermally activated delayed fluorescence (TADF) materials. It was found that DABNA derivatives with multiple-resonance effect achieved a very low lasing threshold. Moreover, advanced light amplification architectures composed of dual DABNA derivatives showed remarkably low lasing thresholds at high concentrations.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Physical
Ryoichi Ishimatsu, Shuya Tashiro, Koji Nakano
Summary: This study investigates the electrogenerated chemiluminescence (ECL) properties of pyrene (Py) and 2,7-di-tert-butylpyrene (di-t-BuPy). The researchers found that the ECL spectra were time-dependent at a commonly employed concentration (1 mM), and the shape of the spectra at a low concentration range (20-30 μM) was determined by isolated pairs of excited (R*) and ground state (R) generated through ion annihilation. Additionally, diffusion equation analysis suggested that the lower excimer formation in di-t-BuPy was due to a longer electron transfer distance between the radical ions.
JOURNAL OF PHYSICAL CHEMISTRY B
(2023)
Proceedings Paper
Engineering, Electrical & Electronic
Seiya Yamamoto, Ryoichi Ishimatsu, Koji Okada, Emiri Kato, Jun Mizuno, Takashi Kasahara
Summary: In this study, we evaluated the performance of a red microfluidic ECL device using DBP as a fluorescent guest. By dissolving rubrene, a well-known yellow fluorescent material, in an organic solvent as the host molecule, the solution with DBP-doped rubrene showed a bright red emission. The electrochemical properties of rubrene and DBP were also analyzed by cyclic voltammetry to understand the emission mechanism.
2022 INTERNATIONAL CONFERENCE ON ELECTRONICS PACKAGING (ICEP 2022)
(2022)
Article
Materials Science, Multidisciplinary
Emma Puttock, Chandana Sampath Kumara Ranasinghe, Mohammad Babazadeh, Jos C. M. Kistemaker, Junhyuk Jang, Mile Gao, David M. Huang, Chihaya Adachi, Paul L. Burn, Paul E. Shaw
Summary: We report the study on thermally activated delayed fluorescence (TADF) poly(dendrimer)s, which are composed of a polymer backbone and dendritic side-chain chromophores. These poly(dendrimer)s exhibit excellent photoluminescence properties and charge transport characteristics.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Materials Science, Multidisciplinary
Tanguy Jousselin-Oba, Masashi Mamada, Karen Wright, Jerome Marrot, Chihaya Adachi, Abderrahim Yassar, Michel Frigoli
Summary: A series of pi-conjugated diindenothienothiophene derivatives (DITTs) with an extended as-indacene core have been synthesized and their closed-shell configuration has been confirmed by X-ray structure analysis. The bond lengths of the diindenoacene diradicaloids show peculiarities, which are influenced by the annellation mode at the outer rings. These featured molecules have low energy band gap and high electron affinities, similar to their benzo-fused indeno[2,1-c]-fluorene counterparts. Analysis of molecule tropicity reveals that the central rings of DITTs have weak antiaromaticity and can be considered as quinoidal molecules bridged by two sulphur atoms. Furthermore, three out of four molecules exhibit ambipolar behavior with moderate mobilities in OFETs.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
