Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 207, Issue -, Pages 819-826Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2014.10.120
Keywords
Bismuth sulfide nanorod; Polyaniline; Electropolymerization; DNA biosensor; Electrochemical impedance spectroscopy
Funding
- National Natural Science Foundation of China [21275127]
- Program for New Century Excellent Talents in Fujian Province University [JA12204]
- Natural Science Foundation of Fujian Province [2011J01059]
Ask authors/readers for more resources
A highly sensitive impedimetric DNA biosensor based on rod-like bismuth sulfide nano (rBi(2)S(3)) and polyaniline (PANI) nanocomposite film modified ionic liquid-carbon paste electrode (IL-CPE) has been developed. The rBi(2)S(3) particles were first dropt on IL-CPE that was constituted with 1-butyl-3-methylimidazolium hexafluorophosphate (BMIMPF6) and graphite powder, and then the PANI polymer was deposited on the surface of rBi(2)S(3) through potentiodynamic polymerization using aniline as the source, forming the PANI capped Bi2S3 nanocomposite. The morphologies and electrocatalytic property of the composite were characterized by scanning electron microscopy (SEM) and electrochemical techniques including electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV), respectively. The integrated advantages such as the large surface area, excellent electronic conductivity, easy to fabrication, and good biocompatibility make the electrode favorable for DNA immobilization and hybridization detection. It was found that remarkable increase of electrochemical impedance wasobserved after the probe DNA modified electrode was hybridized with the target DNA. The dynamic detection range was determined to be from 1.0 x 10(-15) to 1.0 x 10(-11) M with a detection limit of 4.37 x 10(-16) M. The DNA biosensor also displayed good regeneration ability, reproducibility and stability. (C) 2014 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available