Bactericidal Property of Macro-, Micro- and Nanocurcumin: An Assessment

The bactericidal properties of curcumin are well established. In the current communication, we have studied the effect of macro-, micro- and nanocurcumin on their respective bactericidal properties. The bactericidal property was evaluated through interacting curcumin with four predominant pathogenic bacteria. The results demonstrated a fivefold enhancement in bactericidal activity by nanocurcumin. CLSM was instrumental in understanding the mechanism behind the enhanced activity of the nanocurcumin. The higher penetration as shown by the CLSM imaging and the enhanced solubility of the nanocurcumin are speculated to be reasons for the observed superior bactericidal property of nanocurcumin.