Article
Medicine, General & Internal
Neus Altet, Irene Latorre, Maria Angeles Jimenez-Fuentes, Antoni Soriano-Arandes, Raquel Villar-Hernandez, Celia Mila, Pablo Rodriguez-Fernandez, Beatriz Muriel-Moreno, Patricia Comella-del-Barrio, Pere Godoy, Joan-Pau Millet, Maria Luiza de Souza-Galvao, Carlos A. Jimenez-Ruiz, Jose Dominguez
Summary: This study found that exposure to second-hand smoke (SHS) is associated with an increased risk of tuberculosis (TB) and latent TB infection (LTBI) in children. Furthermore, smoking also affects the accuracy of Interferon-Gamma Release Assays (IGRAs) and cytokine immune responses.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Sean Hasan, Belal Alshaikh, Kamran Yusuf
Summary: Our study reveals higher levels of sFasL in pregnant women who smoke, potentially reducing the incidence of preeclampsia by inducing apoptosis of immune cells.
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
(2021)
Article
Multidisciplinary Sciences
Ryan H. Nguyen, Laura B. Vater, Lava R. Timsina, Gregory A. Durm, Katelin Rupp, Keylee Wright, Miranda H. Spitznagle, Brandy Paul, Shadia Jalal, Lisa Carter-Harris, Karen S. Hudmon, Nasser H. Hanna, Patrick J. Loehrer, DuyKhanh P. Ceppa
Summary: The study found that counties with stronger smoke-free air ordinances had lower smoking rates and fewer new lung cancer cases per year. Therefore, strengthening smoke-free air ordinances is crucial for reducing lung cancer incidence.
Article
Cell Biology
Chao Cao, Baoping Tian, Xinwei Geng, Hongbin Zhou, Zhiwei Xu, Tianwen Lai, Yanping Wu, Zhengqiang Bao, Zhihua Chen, Wen Li, Huahao Shen, Songmin Ying
Summary: Chronic inflammation has been identified as a risk factor for human cancer, and this study showed that cigarette smoke-induced genomic instability may be partially attributed to IL-17-mediated inflammation. Higher levels of IL-17 and DDR were observed in smokers' lung tissues compared to non-smokers, as well as in mice exposed to cigarette smoke. These findings suggest that IL-17 could play a crucial role in the development of lung cancer.
Article
Immunology
Courtney Lynn Schubert, Kamran Yusuf
Summary: This study compared the serum levels of related factors in smoking and non-smoking pregnant women and found that TGF-β1 levels were significantly higher in smoking mothers, which may help explain the lower risk of preeclampsia in smoking mothers.
JOURNAL OF REPRODUCTIVE IMMUNOLOGY
(2021)
Article
Critical Care Medicine
Farzad Moazed, Carolyn Hendrickson, Alejandra Jauregui, Jeffrey Gotts, Amanda Conroy, Kevin Delucchi, Hanjing Zhuo, Mikhaela Arambulo, Kathryn Vessel, Serena Ke, Thomas Deiss, Amy Ni, Aleksandra Leligdowicz, Jason Abbott, Mitchell J. Cohen, Pratik Sinha, Antonio Gomez, Kirsten Kangelaris, Lucy Kornblith, Michael Matthay, Neal Benowitz, Kathleen Liu, Carolyn S. Calfee
Summary: Cigarette smoke exposure is associated with an increased risk of developing ARDS in both pulmonary and nonpulmonary sepsis patients. Among ARDS patients, those with exposure to cigarette smoke have lower systemic inflammation levels, and active smokers also have lower severity of illness compared to non-smokers, indicating that smoking contributes to biological heterogeneity in ARDS.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Medicine, Research & Experimental
Tingting Wu, Keye Xu, Chaobo Liu, Yan Li, Mingcai Li
Summary: This study aimed to investigate the effect of interleukin-37 (IL-37) on cigarette smoke-induced lung inflammation. By administering IL-37-expressing lentivirus to mice, it was found that IL-37 can alleviate weight loss and pulmonary inflammation induced by cigarette smoke. IL-37 also significantly inhibited inflammatory cell recruitment, reduced inflammatory cell increase, and suppressed the production of pro-inflammatory cytokines.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Biochemistry & Molecular Biology
Naserddine Hamadi, Sumaya Beegam, Nur Elena Zaaba, Ozaz Elzaki, Mariam Abdulla Altamimi, Abderrahim Nemmar
Summary: Waterpipe smoking (WPS) is popular in Asian and Middle Eastern countries and has gained popularity worldwide, especially among youth. Chronic exposure to WPS is associated with inflammation, oxidative stress, apoptosis, microgliosis, and astrogliosis in the cerebellum. These effects involve the activation of NF-kappa B.
Article
Biotechnology & Applied Microbiology
Moon-shong Tang, Hyun-Wook Lee, Mao-wen Weng, Hsiang-Tsui Wang, Yu Hu, Lung-Chi Chen, Sung-Hyun Park, Huei-wei Chan, Jiheng Xu, Xue-Ru Wu, He Wang, Rui Yang, Karen Galdane, Kathryn Jackson, Annie Chu, Elizabeth Halzack
Summary: The allure of tobacco smoking and e-cigarettes lies in the instant gratification from nicotine inhalation. However, both forms of smoking contribute to DNA damage and inhibit DNA repair, increasing the risk of cancer.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
(2022)
Article
Medicine, Research & Experimental
Yi Lu, Yuanpu Peter Di, Ming Chang, Xin Huang, Qiuyan Chen, Ni Hong, Beth A. Kahkonen, Marissa E. Di, Chunyan Yu, Evan T. Keller, Jian Zhang
Summary: The study found that cigarette smoke exposure significantly disrupts the balance between bone resorption and bone formation. Short-term smoke exposure effectively induces osteoclast activity and inhibits osteoblast differentiation.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Aimee Kroll-Desrosiers, Cathryn Glanton Holzhauer, Lindsey Russo, Eric C. DeRycke, Rebecca L. Kinney, Lori A. Bastian, Kristin M. Mattocks
Summary: The study found a high smoking rate during pregnancy, but more than half of women successfully quit smoking during pregnancy. Early initiation of prenatal care, living without household smokers, and having it not be a first pregnancy were significant predictors of quitting versus persistent smoking during pregnancy.
WOMENS HEALTH ISSUES
(2021)
Article
Microbiology
Danicke Willemse, Chivonne Moodley, Smriti Mehra, Deepak Kaushal
Summary: Smoking is a known added risk factor for tuberculosis, increasing the risk of active TB and reducing cure and treatment completion rates. Cigarette smoke contains harmful compounds that may potentially enhance the virulence of the tubercle bacilli. Further research is needed to explore the impact of cigarette smoke on Mycobacterium tuberculosis and its potential implications for TB treatment efficacy.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Immunology
Tiantian Cen, Yifeng Mai, Jie Jin, Minxuan Huang, Mingcai Li, Shanshan Wang, Hongying Ma
Summary: Our study aimed to investigate the ability of IL-41 to protect against CS-induced lung inflammation in vivo. The results showed that IL-41 pre-treatment alleviated pulmonary inflammatory infiltration and lung tissue lesions, limited CS-induced weight loss, and promoted the polarization of M2 macrophages. IL-41 also increased the levels of IL-10 and reduced the production of TNF-α, IL-6, and IL-1β.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Review
Environmental Sciences
Yubin Liu, Lan Lu, Huan Yang, Xu Wu, Xinyue Luo, Jing Shen, Zhangang Xiao, Yueshui Zhao, Fukuan Du, Yu Chen, Shuai Deng, Chi Hin Cho, Qianxiu Li, Xiaobing Li, Wanping Li, Fang Wang, Yuhong Sun, Li Gu, Meijuan Chen, Mingxing Li
Summary: This article provides a comprehensive review on the impact of cigarette smoking on inflammation and cancer. It discusses the harmful chemicals in cigarettes, the effect of smoking on the immune system, and the molecular mechanisms by which smoking induces inflammation and cancer.
ENVIRONMENTAL POLLUTION
(2023)
Article
Medicine, Research & Experimental
Hongmei Tang, Yun Zhang, Qiao Wang, Ziling Zeng, Xiaoyun Wang, Yuejiao Li, Zhibin Wang, Ning Ma, Guofeng Xu, Xiaolin Zhong, Linlin Guo, Xiefang Yuan, Xing Wang
Summary: This study found that astaxanthin can attenuate DNA damage and apoptosis caused by cigarette smoke, and reduce the activation of Caspase-3. Astaxanthin can also decrease the production of intracellular reactive oxygen species by suppressing the expression of NOX4 and DUOX1.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Oncology
Glenda Nicioli da Silva, Leandro Toshio Filoni, Maria Cecilia Salvadori, Daisy Maria Favero Salvadori
PATHOLOGY & ONCOLOGY RESEARCH
(2018)
Article
Genetics & Heredity
Cristiana M. M. Freire, Mariana G. Braz, Joao Paulo C. Marcondes, Nayara M. Arruda, Jose Reinaldo C. Braz, Claudia A. Rainho, Leandro G. Braz, Daisy M. F. Salvadori
Article
Biotechnology & Applied Microbiology
Fabio Henrique Fernandes, Gisela de Aragao Umbuzeiro, Daisy Maria Favero Salvadori
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
(2019)
Article
Reproductive Biology
Maruhen A. D. Silveira, Joao Paulo C. Marcondes, Juliana R. Lara, Wellerson R. Scarano, Iracema M. P. Calderon, Marilza V. C. Rudge, Daisy M. F. Salvadori
REPRODUCTIVE TOXICOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Marilza Vieira Cunha Rudge, Angelica Mercia Pascon Barbosa, Luis Sobrevia, Rafael Bottaro Gelaleti, Raghavendra Lakshmana Shetty Hallur, Joao Paulo Castro Marcondes, Daisy Maria Favero Salvadori, Caroline Baldini Prudencio, Claudia Garcia Magalhaes, Roberto Costa, Joelcio Francisco Abbade, Jose Eduardo Corrente, Iracema de Mattos Paranhos Calderon, M. Rudge, I. M. P. Calderon, A. P. Barbosa, J. Abbade, R. A. A. Costa, C. G. Magalhaes, D. F. Salvadori, R. Gelaleti, R. L. S. Hallur, J. P. Marcondes, J. F. Floriano, D. R. A. Reyes, L. Sobrevia, C. B. Prudencio, F. Piculo, G. Marini, G. Vesentini, G. Morceli, C. A. Negrato, H. D. Prazeres, S. Molina, M. Arantes, A. C. Cavassini, L. Kerche, A. K. C. De Luca, S. Correa-Silva, E. Bevilacqua, J. B. Moreli, L. Pietro, S. Daher, S. Fabio, A. C. Honorio-Franca, A. A. Queiroz, C. C. P. Hara, C. A. L. Boraschi, T. A. V. L. Pauletti, L. Jovanovic, A. Dias, A. N. Atallah, M. D. Ramos, M. A. M. Brasil, C. V. C. Rudge, A. Tristao, U. Del Nero, M. Mendonca, S. S. Witkin, C. Sartorao Filho, S. K. Nuens, F. A. Pinheiro, S. Quiroz, T. Pascon, T. D. Caldeirao, A. P. Oliveira, B. F. Nicolosi, C. Bolognani, D. L. G. Fagundes, I. C. F. Llanos, J. M. Vernini, L. B. S. M. Reis, M. P. Sirimarco, N. M. Basso, N. A. Q. Maquesim, S. A. L. C. Silva, S. C. Silva, T. T. Scudeller, W. Ayach, A. P. M. Almeida, B. F. C. A. Nicolosi, C. P. Lima, D. Luminoso, F. C. Vasconcellos, G. A. R. Ferraz, H. Migiolaro, L. P. Camargo, M. L. S. Macedo, M. R. K. Rodrigues, P. H. O. Anezio
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2020)
Article
Environmental Sciences
Bertha Irina Gastelbondo-Pastrana, Fabio Henrique Fernandes, Daisy Maria Favero Salvadori, Daniela Carvalho dos Santos
Article
Biochemistry & Molecular Biology
Luciana Maria Feliciano, Andre Luiz Ventura Savio, Joao Paulo de Castro Marcondes, Glenda Nicioli da Silva, Daisy Maria Favero Salvadori
JOURNAL OF MOLECULAR NEUROSCIENCE
(2020)
Article
Environmental Sciences
Maria Esther Suarez Alpire, Elaine Aparecida de Camargo, Caroline Margonato Cardoso, Daisy Maria Favero Salvadori, Camilo Dias Seabra Pereira, Daniel Araki Ribeiro
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2020)
Article
Obstetrics & Gynecology
Marilza V. C. Rudge, Fatima P. Souza, Joelcio F. Abbade, Raghavendra L. S. Hallur, Joao Paulo C. Marcondes, Fernanda Piculo, Gabriela Marini, Giovana Vesentini, Lehana Thabane, Steven S. Witkin, Iracema M. P. Calderon, Angelica M. P. Barbosa, M. V. Rudge, A. M. P. Barbosa, I. M. P. Calderon, F. P. Souza, J. F. Abbade, L. S. R. Hallur, F. Piculo, G. Marini, G. Vesentini, L. Thabane, M. S. Palma, C. F. O. Graeff, R. K. Arni, R. D. Herculano, D. F. Salvadori, S. Mateus, M. Dal Pai Silva, C. G. Magalhaes, R. A. Costa, S. A. M. Lima, S. L. Felisbino, W. Barbosa, A. Atallah, M. J. B. Girao, Z. Di Bella, S. M. Uchoa, S. Payao, A. Hijas, B. Berghman, R. De Bie, L. Sobrevia, B. Junginger, F. C. B. Alves, P. S. Rossignoli, C. B. Prudencio, M. I. G. Orlandi, M. I. Goncalves, S. K. Nunes, B. B. Catinelli, S. Quiroz, B. V. Sarmento, F. A. Pinheiro, C. I. Sartorao, R. R. Lucas, D. R. A. Reyes, S. B. C. V. Quiroz, E. M. A. Enriquez, R. G. Oliveira, J. F. Floriano, J. P. C. Marcondes, S. Barneze, T. D. Dangio, T. Pascon, P. Rossignoli, J. V. Freitas, L. Takano, F. Reis, T. D. Caldeirao, J. N. Fernandes, A. M. Carr, M. V. C. Gaitero, J. E. Corrente, H. R. C. Nunes, A. F. Candido, S. M. B. Costa, T. D. Dangio, T. Pascon, J. V. F. Melo, L. Takano, F. V. D. S. Reis, T. D. Caldeirao, A. M. Carr, G. A. Garcia, G. B. Rabadan, H. C. M. Bassin, K. S. Suyama, L. N. Damasceno, M. L. S. Takemoto, M. D. Menezes, D. G. Bussaneli, V. K. C. Nogueira, P. R. Lima, I. O. Lourenco, J. Marostica de Sa, R. A. Megid, I. P. Caruso, L. T. Rasmussen, G. M. Prata, F. Piculo, G. Vesentini, M. A. Arantes, G. A. R. Ferraz, L. P. Camargo, M. R. Kron, J. E. Corrente, H. R. C. Nunes
BMC PREGNANCY AND CHILDBIRTH
(2020)
Article
Pharmacology & Pharmacy
Leonardo da Cunha Menezes Souza, Fabio Henrique Fernandes, Paula Torres Presti, Ana Lucia Anjos Ferreira, Daisy Maria Favero Salvadori
Summary: This study investigated the molecular mechanisms underlying DOX cardiotoxicity and the cardioprotective effect of Alda-1. Treatment with DOX led to progressive cardiac tissue injury and altered lipid profile, but Alda-1 administration reduced histopathological injuries and restored Slc27a2 overexpression. The findings suggest a relationship between DOX exposure and FABP4 and Slc27a2 overexpression in the development of DOX-mediated cardiomyopathy.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
Article
Environmental Sciences
Amanda Rodrigues Tanamachi, Fabio Henrique Fernandes, Josiane Aparecida de Souza Vendemiatti, Patricia Prediger, Natalia Gabriele Camparotto, Noeme Sousa Rocha, Gisela Aragao Umbuzeiro, Daisy Maria Favero Salvadori
Summary: This study found that certain dinitrophenylazo dyes and their resulting PBTAs, discovered in wastewater from textile plants, cause genetic damage to DNA and cells in mice, and increase the frequency of micronucleated cells.
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
(2021)
Article
Agronomy
Carla Fredrichsen Moya, Marcelo Piagentini, Danilo da Cunha Silva, Fabio Henrique Fernandes, Daisy Maria Favero Salvadori, Eunice Oba
Summary: The study evaluated the effects of different concentrations of selenium on sperm DNA integrity in male ovines, with results suggesting that selenium supplementation can decrease DNA damage in sperm cells.
Meeting Abstract
Environmental Sciences
A. R. Tanamachi, F. H. Fernandes, J. S. Vendemiatti, P. Prediger, G. A. Umbuzeiro, D. M. F. Salvadori
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
(2019)
Meeting Abstract
Environmental Sciences
A. L. Ventura Savio, K. R. Moreira Leite, S. Burns, G. N. da Silva, P. A. Favaretto Galante, L. O. Ferraz Penalva, D. M. Favero Salvadori
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
(2018)
Meeting Abstract
Oncology
Andre Luiz Ventura Savio, Ricardo Piuco, Katia Ramos Moreira Leite, Daisy Maria Favero Salvadori, Pedro Alexandre Favoretto Galante, Luiz Otavio Ferraz Penalva
CLINICAL CANCER RESEARCH
(2018)