Quantitative comparison between in vivo DNA adduct formation from exposure to selected DNA-reactive carcinogens, natural background levels of DNA adduct formation and tumour incidence in rodent bioassays

Detection of 7-(2′-Carboxyethyl)guanine but Not 7-Carboxymethylguanine in Human Liver DNA

(2010) Guang Cheng et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic

(2010) Diane Benford et al.   FOOD AND CHEMICAL TOXICOLOGY

A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes

(2010) Alicia Paini et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

(2009) Kent S. Gates   CHEMICAL RESEARCH IN TOXICOLOGY

Application of Key Events Analysis to Chemical Carcinogens and Noncarcinogens

(2009) Alan R. Boobis et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Risk assessment of chemical carcinogens and thresholds

(2009) Hans-Günter Neumann   CRITICAL REVIEWS IN TOXICOLOGY

Creating context for the use of DNA adduct data in cancer risk assessment: I. Data organization

(2009) Annie M. Jarabek et al.   CRITICAL REVIEWS IN TOXICOLOGY

Creating context for the use of DNA adduct data in cancer risk assessment: II. Overview of methods of identification and quantitation of DNA damage

(2009) Matthew W. Himmelstein et al.   CRITICAL REVIEWS IN TOXICOLOGY

8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis

(2009) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Biological significance of DNA adducts: Comparison of increments over background for various biomarkers of genotoxicity in L5178Y tk+/− mouse lymphoma cells treated with hydrogen peroxide and cumene hydroperoxide

(2009) Andreas Brink et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

ECETOC workshop on the biological significance of DNA adducts: Summary of follow-up from an Expert Panel Meeting

(2009) Lynn H. Pottenger et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The formation and biological significance of N7-guanine adducts

(2009) Gunnar Boysen et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Use of Physiologically Based Biokinetic (PBBK) Modeling to Study Estragole Bioactivation and Detoxification in Humans as Compared with Male Rats

(2009) Ans Punt et al.   TOXICOLOGICAL SCIENCES

Mutagenicity of tamoxifen DNA adducts in human endometrial cells and in silico prediction of p53 mutation hotspots

(2008) E. Liapis et al.   NUCLEIC ACIDS RESEARCH

Simultaneous determination of 8-oxo-2′-deoxyguanosine and 8-oxo-2′-deoxyadenosine in DNA using online column-switching liquid chromatography/tandem mass spectrometry

(2008) Rajinder Singh et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat

(2008) Ans Punt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Application of mode-of-action considerations in human cancer risk assessment

(2008) Gary M. Williams   TOXICOLOGY LETTERS

Biomarkers in Toxicology and Risk Assessment: Informing Critical Dose–Response Relationships

(2007) James A. Swenberg et al.   CHEMICAL RESEARCH IN TOXICOLOGY