Fluorescence Spectroscopy and Chemometric Modeling for Bioprocess Monitoring

Comprehensive, quantitative bioprocess productivity monitoring using fluorescence EEM spectroscopy and chemometrics

(2014) Boyan Li et al.   ANALYST

Simultaneous determination of aromatic amino acids in different systems using three-way calibration based on the PARAFAC-ALS algorithm coupled with EEM fluorescence: exploration of second-order advantages

(2014) Chao Kang et al.   Analytical Methods

Wheat flour characterization using NIR and spectral filter based on Ant Colony Optimization

(2014) Cassiano Ranzan et al.   CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS

Multivariate PAT solutions for biopharmaceutical cultivation: current progress and limitations

(2014) Sarah M. Mercier et al.   TRENDS IN BIOTECHNOLOGY

Fluorescence spectroscopy and multi-way techniques. PARAFAC

(2013) Kathleen R. Murphy et al.   Analytical Methods

Real-time estimation of glucose concentration in algae cultivation system using Raman spectroscopy

(2013) Se-Kyu Oh et al.   BIORESOURCE TECHNOLOGY

Evaluation of wavelength selection methods for 2D fluorescence spectra applied to bioprocesses characterization

(2013) S. S. Masiero et al.   BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING

2D-fluorescence and multivariate data analysis for monitoring of sourdough fermentation process

(2013) Bianca Grote et al.   FOOD CONTROL

Use of NAD(P)H Fluorescence Measurement for On-Line Monitoring of Metabolic State of Azohydromonas australica in Poly(3-hydroxybutyrate) Production

(2012) Geeta Gahlawat et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Chemometric modeling and two-dimensional fluorescence analysis of bioprocess with a new strain of Klebsiella pneumoniae to convert residual glycerol into 1,3-propanediol

(2012) Daniele Misturini Rossi et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

A new and efficient variable selection algorithm based on ant colony optimization. Applications to near infrared spectroscopy/partial least-squares analysis

(2011) Franco Allegrini et al.   ANALYTICA CHIMICA ACTA

In situ sensor techniques in modern bioprocess monitoring

(2011) Sascha Beutel et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

On-line monitoring of recombinant bacterial cultures using multi-wavelength fluorescence spectroscopy

(2011) Garima Jain et al.   BIOCHEMICAL ENGINEERING JOURNAL

On-line high performance liquid chromatography measurements of extracellular metabolites in an aerobic batch yeast (Saccharomyces cerevisiae) culture

(2011) Niina Tohmola et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

In-line monitoring of Saccharomyces cerevisiae fermentation with a fluorescence probe: new approaches to data collection and analysis

(2011) Andrey Bogomolov et al.   JOURNAL OF CHEMOMETRICS

Introducing process analytical technology (PAT) in filamentous cultivation process development: comparison of advanced online sensors for biomass measurement

(2011) Nanna Petersen Rønnest et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Prediction of Cell Culture Media Performance Using Fluorescence Spectroscopy

(2010) Paul W. Ryan et al.   ANALYTICAL CHEMISTRY

Sensor combination and chemometric variable selection for online monitoring of Streptomyces coelicolor fed-batch cultivations

(2010) Peter Ödman et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Evaluation of software sensors for on-line estimation of culture conditions in an Escherichia coli cultivation expressing a recombinant protein

(2010) Benedikt Warth et al.   JOURNAL OF BIOTECHNOLOGY

On-line estimation of biomass, glucose and ethanol in Saccharomyces cerevisiae cultivations using in-situ multi-wavelength fluorescence and software sensors

(2009) Peter Ödman et al.   JOURNAL OF BIOTECHNOLOGY

Validation of a high-throughput fermentation system based on online monitoring of biomass and fluorescence in continuously shaken microtiter plates

(2009) Frank Kensy et al.   Microbial Cell Factories

Quality by design for biopharmaceuticals

(2009) Anurag S Rathore et al.   NATURE BIOTECHNOLOGY

Model based substrate set point control of yeast cultivation processes based on FIA measurements

(2008) Christine Klockow et al.   ANALYTICA CHIMICA ACTA

On-line Characterization of Physiological State in Poly(β-Hydroxybutyrate) Production by Wautersia eutropha

(2008) Shilpi Khanna et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

In situ 2D fluorometry and chemometric monitoring of mammalian cell cultures

(2008) Ana P. Teixeira et al.   BIOTECHNOLOGY AND BIOENGINEERING

Use of NADH fluorescence measurement for on-line biomass estimation and characterization of metabolic status in bioreactor cultivation of plant cells for azadirachtin (a biopesticide) production

(2008) Smita Srivastava et al.   PROCESS BIOCHEMISTRY

Plant Cell Culture Monitoring Using an in Situ Multiwavelength Fluorescence Probe

(2005) Steve Hisiger et al.   BIOTECHNOLOGY PROGRESS

Evaluation of Multiwavelength Culture Fluorescence for Monitoring the Aroma Compound 4-Hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2H)-furanone (HEMF) Production

(2004) A. Hagedorn et al.   BIOTECHNOLOGY PROGRESS