Article
Clinical Neurology
Tobia Zanotto, Jacob J. Sosnoff, Edward Ofori, Daniel Golan, Myassar Zarif, Barbara Bumstead, Marijean Buhse, Olivia Kaczmarek, Jeffrey Wilken, Lisa Muratori, Thomas J. Covey, Mark Gudesblatt
Summary: This study aimed to quantify the variability of spatiotemporal gait measures within homologous EDSS categories. The results showed that there was a correlation between gait measures and EDSS scores, and the variability of gait measures increased with the increase in EDSS categories. Therefore, more comprehensive objective metrics are needed to accurately evaluate disability in pwMS, in addition to the EDSS.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2022)
Article
Clinical Neurology
Floor C. C. Loonstra, Kim F. F. Falize, Lodewijk R. J. de Ruiter, Menno M. M. Schoonheim, Eva M. M. Strijbis, Joep Killestein, Helga E. E. de Vries, Bernard M. J. Uitdehaag, Merel Rijnsburger
Summary: The study found that adiponectin, leptin, and resistin, hormones secreted by white adipose tissue, are associated with the severity of multiple sclerosis (MS) independent of body mass index (BMI). The results suggest that these adipokines play an important role in the pathogenesis of MS.
JOURNAL OF NEUROLOGY
(2023)
Article
Health Care Sciences & Services
Maia P. Smith
Summary: This study found that under most conditions, the majority of COVID-19 morbidity was in survivors. Future research should investigate the incidence, risk factors, and clinical course of long-COVID to elucidate the total disease burden, and decisionmakers should allocate scarce resources to minimize total morbidity.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2022)
Article
Biodiversity Conservation
Qin Li, Xiaojun Kou
Summary: The study introduces a new index, WiBB, which combines information theory, standardized regression coefficient, and bootstrap resampling techniques. Through evaluations on simulated and empirical datasets, it demonstrates the superiority of WiBB in evaluating predictor importance.
Article
Clinical Neurology
Steve Simpson-Yap, Nupur Nag, Yasmine Probst, George Jelinek, Sandra Neate
Summary: The study found that better quality of diet and avoiding meat consumption were associated with reduced disability progression in people with MS. Consumption of dairy products showed mixed associations in both cross-sectional and prospective analyses.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Clinical Neurology
V Lepore, C. Bosetti, C. Santucci, P. Iaffaldano, M. Trojano, P. Mosconi
Summary: This study compared the use of fixed baseline and roving EDSS reference scores in detecting disability-worsening events in RRMS patients, and found that roving EDSS reference scores were more sensitive in detecting worsening events unrelated to relapse.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Psychology, Clinical
Maciej Wilski, Waldemar Brola, Magdalena Koper, Jaros law Gabryelski, Magdalena Luniewska, Ma lgorzata Fudala, Maciej Tomczak
Summary: This study aimed to examine the association between habitual physical activity and coping effectiveness in people with multiple sclerosis (MS), and to determine the extent to which self-efficacy acts as a mediator in this relationship. The findings indicated a positive correlation between engagement in physical activity and self-efficacy among participants with high and medium disability levels. Moreover, physical activity was associated with improved psychosocial functioning in people with high levels of disability caused by MS.
INTERNATIONAL JOURNAL OF CLINICAL AND HEALTH PSYCHOLOGY
(2024)
Article
Psychiatry
Mark Zimmerman, Justine S. Thompson, Daniel M. Mackin
Summary: The evaluation of depression treatment outcomes should consider broader factors beyond symptom improvement, such as well-being, life satisfaction, and coping ability.
PSYCHIATRY RESEARCH
(2022)
Article
Multidisciplinary Sciences
Yajun Wang, Shan Ye, Lu Chen, Lu Tang, Dongsheng Fan
Summary: Weight loss is common in ALS patients and often due to loss of appetite. Emotional issues like anxiety and depression can contribute to appetite loss in ALS patients, highlighting the importance of early intervention to prevent weight loss.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Franziska Di Pauli, Anne Zinganell, Bettina Boettcher, Janette Walde, Michael Auer, Robert Barket, Klaus Berek, Alexander Egger, Andrea Griesmacher, Natasa Sukalo, Florian Deisenhammer, Harald Hegen
Summary: The prevalence of sexual dysfunction (SD) in people with multiple sclerosis (pwMS) is 47%. Risk factors for SD in pwMS include smoking, disability, depression, and bladder and bowel dysfunction, while the use of disease-modifying treatment lowers the risk. SD is associated with worse quality of life and lower physical activity. Screening for SD is recommended, especially in patients with disability, depression, or bladder and bowel dysfunction.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Psychology, Multidisciplinary
Renzo Bianchi, Guadalupe Manzano-Garcia, Jean-Pierre Rolland
Summary: The study found consistent associations between burnout and neuroticism, job strain, skill development, security in daily life, and work-non-work conflict across the three samples. Predictors of burnout included factors such as sex, age, unreasonable work tasks, weekly working hours, job autonomy, and support in personal life. Neuroticism was identified as the best predictor of burnout in each sample.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Clinical Neurology
Masaaki Niino, Shoko Fukumoto, Tatsusada Okuno, Nobuo Sanjo, Hikoaki Fukaura, Masahiro Mori, Takashi Ohashi, Hideyuki Takeuchi, Yuko Shimizu, Juichi Fujimori, Izumi Kawachi, Jun-Ichi Kira, Eri Takahashi, Yusei Miyazaki, Nobuhiro Mifune
Summary: This study assessed the association of HRQOL with disabilities, fatigue, and depression in Japanese subjects with MS. The results showed that HRQOL had relatively close correlations with disabilities and fatigue, and depression had an especially close relationship with HRQOL.
JOURNAL OF NEUROLOGY
(2023)
Article
Medicine, General & Internal
Moran Livne-Margolin, Itay Tokatly Latzer, Orit Pinhas-Hamiel, Gil Harari, Anat Achiron
Summary: The study found that the disability level in individuals with MS was not correlated with disease duration, lifestyle habits, or overweight/obesity, but was associated with central obesity.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Emily M. Bartholomay, Stephanie Cox, Lawrence Tabone, Nova Szoka, Salim Abunnaja, Laura Aylward
Summary: The study aims to investigate the relationship between coping, anxiety, depression, and weight loss after bariatric surgery. It found that intrapersonal coping strategies used before the surgery predicted weight loss 24 months after the surgery, while interpersonal coping and maladaptive coping were not related to weight loss. Baseline anxiety and depression also did not predict weight loss after the surgery.
Article
Medicine, General & Internal
Silvia Cerea, Marta Ghisi, Marco Pitteri, Maddalena Guandalini, Lauren B. Strober, Simona Scozzari, Francesco Crescenzo, Massimiliano Calabrese
Summary: This study found that coping strategies have a significant impact on Health-Related Quality of Life and physical disability in patients with multiple sclerosis, highlighting the importance of adaptive coping strategies for better physical and mental health outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Roberto Mediavilla, Eduardo Fernandez-Jimenez, Gonzalo Martinez-Ales, Berta Moreno-Kustner, Irene Martinez-Morata, Fabiola Jaramillo, Ines Moran-Sanchez, Sergio Minue, Alberto Torres-Cantero, Ruben Alvarado, Jose Luis Ayuso-Mateos, Franco Mascayano, Ezra Susser, Maria-Fe Bravo-Ortiz
Summary: During the initial COVID-19 outbreak, healthcare workers faced various work-related stressors, such as inadequate protective equipment, changes in job functions, and patient prioritization decision-making, all of which were associated with symptoms of depression and psychological distress.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Franco Mascayano, Els van der Ven, Maria Francesca Moro, Sara Schilling, Sebastian Alarcon, Josleen Al Barathie, Lubna Alnasser, Hiroki Asaoka, Olatunde Ayinde, Arin A. Balalian, Armando Basagoitia, Kirsty Brittain, Bruce Dohrenwend, Sol Durand-Arias, Mehmet Eskin, Eduardo Fernandez-Jimenez, Marcela Ines Freytes Frey, Luis Gimenez, Lydia Gisle, Hans W. Hoek, Rodrigo Ezequiel Jaldo, Jutta Lindert, Humberto Maldonado, Gonzalo Martinez-Ales, Carmen Martinez-Viciana, Roberto Mediavilla, Clare McCormack, Landon Myer, Javier Narvaez, Daisuke Nishi, Uta Ouali, Victor Puac-Polanco, Jorge Ramirez, Alexandra Restrepo-Henao, Eliut Rivera-Segarra, Ana M. Rodriguez, Dahlia Saab, Dominika Seblova, Andrea Tenorio Correia da Silva, Linda Valeri, Ruben Alvarado, Ezra Susser
Summary: This paper describes the protocol of the ongoing global study, HEROES, which aims to track the mental health symptoms and disorders of healthcare workers during the COVID-19 pandemic. The study includes participants from various healthcare settings in different countries, with data collected over a two-year follow-up period. The results so far have recruited over 34,000 healthcare workers, providing valuable insights into the impact of the pandemic on their mental well-being.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Article
Geriatrics & Gerontology
Eduardo Fernandez-Jimenez, Ainoa Munoz-Sanjose, Roberto Mediavilla, Gonzalo Martinez-Ales, Iker I. Louzao, Jorge Andreo, Susana Cebolla, Maria-Fe Bravo-Ortiz, Carmen Bayon
Summary: The study found that NLR at hospital admission can predict subsequent delirium in older COVID-19 patients, especially in those aged between 69 and 80, with a higher risk. There were no differences in the association between baseline NLR and delirium by sex, and SII was not able to predict delirium development.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Psychiatry
Esther Ortiz-Calvo, Gonzalo Martinez-Ales, Roberto Mediavilla, Elisabeth Gonzalez-Gomez, Eduardo Fernandez-Jimenez, Maria-Fe Bravo-Ortiz, Berta Moreno-Kustner
Summary: The study found that resilience and self-perceived social support may help protect healthcare workers from the impacts of mental health problems, especially during the COVID-19 pandemic. Public health strategies targeting these potential protective factors may help reduce the impact of the pandemic on healthcare workers' mental health.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychiatry
Gonzalo Martinez-Ales, Eduardo Fernandez-Jimenez, Roberto Mediavilla, Manuel Quintana-Diaz, Iker Louzao, Susana Cebolla, Ainoa Munoz-Sanjose, Carmen Bayon, Ezra S. Susser, Maria Fe Bravo-Ortiz
Summary: This study examined whether excess chronic medical comorbidity mediated excess COVID-19 inpatient mortality among people with mental disorders in the early phase of the pandemic. The findings suggest that a large proportion of excess COVID-19 mortality among people with mental disorders may be explained by factors other than comorbidity.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Article
Multidisciplinary Sciences
Blanca Garcia-Vazquez, Gonzalo Martinez-Ales, Eduardo Fernandez-Jimenez, Jorge Andreo-Jover, Berta Moreno-Kustner, Sergio Minue, Fabiola Jaramillo, Ines Moran-Sanchez, Irene Martinez-Morata, Jose Luis Ayuso-Mateos, Carmen Bayon, Maria-Fe Bravo-Ortiz, Roberto Mediavilla
Summary: This study describes the use of psychological support among healthcare workers in Spain following the initial outbreak of COVID-19 and explores its association with workplace and COVID-19-related factors.
Article
Public, Environmental & Occupational Health
Roberto Mediavilla, Eduardo Fernandez-Jimenez, Irene Martinez-Morata, Fabiola Jaramillo, Jorge Andreo-Jover, Ines Moran-Sanchez, Franco Mascayano, Berta Moreno-Kustner, Sergio Minue, Jose Luis Ayuso-Mateos, Richard A. Bryant, Maria-Fe Bravo-Ortiz, Gonzalo Martinez-Ales
Summary: This study characterizes the evolution of healthcare workers' mental health status over a 1-year period following the initial COVID-19 pandemic outbreak and identifies baseline characteristics associated with resolution or persistence of mental health problems over time. The results show that poor mental health outcomes among healthcare workers persisted over time, highlighting the need for occupational programs and mental health strategies.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2022)
Meeting Abstract
Psychiatry
M. J. Maldonado-Belmonte, E. Fernandez-Jimenez, M. T. Sanchez-Polo
EUROPEAN PSYCHIATRY
(2021)
Meeting Abstract
Psychiatry
I. Torrea-Araiz, E. Fernandez-Jimenez, G. Navarro-Oliver, E. Vidal-Bermejo, T. Castellanos-Villaverde, A. Hospital-Moreno
EUROPEAN PSYCHIATRY
(2021)
Meeting Abstract
Psychiatry
E. Vidal-Bermejo, E. Fernandez-Jimenez, T. Castellanos-Villaverde, I. Torrea-Araiz, G. Navarro-Oliver, A. Hospital-Moreno
EUROPEAN PSYCHIATRY
(2021)
Meeting Abstract
Psychiatry
T. Castellanos-Villaverde, E. Fernandez-Jimenez, E. Vidal-Bermejo, I. Torrea-Araiz, G. Navarro-Oliver, A. Hospital-Moreno
EUROPEAN PSYCHIATRY
(2021)
Meeting Abstract
Psychiatry
E. Fernandez-Jimenez, E. Vidal-Bermejo, I. Torrea-Araiz, T. Castellanos-Villaverde, G. Navarro-Oliver, A. Hospital-Moreno
EUROPEAN PSYCHIATRY
(2021)
Meeting Abstract
Psychiatry
G. Navarro-Oliver, E. Fernandez-Jimenez, I. Torrea-Araiz, T. Castellanos-Villaverde, E. Vidal-Bermejo, A. Hospital-Moreno
EUROPEAN PSYCHIATRY
(2021)
Article
Psychology, Multidisciplinary
Eduardo Fernandez-Jimenez, Ivan Panyavin, Maria Angeles Perez-San-Gregorio, Maria T. Schultheis
Summary: This study compared QoL and depressive symptomatology between Spanish and American MS patients, finding that Spaniards showed worse depressive symptomatology and QoL, while Americans mainly suffered impairment in physical domains. The interrelationship between different QoL dimensions also varied between the two countries, with different predictors for depressive symptomatology observed.
Meeting Abstract
Psychiatry
M. J. Maldonado-Belmonte, E. Fernandez-Jimenez, J. M. Roman-Belmonte
EUROPEAN PSYCHIATRY
(2021)