Composite end points to assess delay of disability progression by MS treatments

Disability outcome measures in multiple sclerosis clinical trials: current status and future prospects

(2012) Jeffrey A Cohen et al.   LANCET NEUROLOGY

EDSS variability before randomization may limit treatment discovery in primary progressive MS

(2012) Jiameng Zhang et al.   Multiple Sclerosis Journal

EDSS improvement: recovery of function or noise?

(2012) Daniel Ontaneda et al.   Multiple Sclerosis Journal

Quality of life reporting in multiple sclerosis clinical trials: enough quality?

(2012) Alessandra Solari   Multiple Sclerosis Journal

The natural history of multiple sclerosis, a geographically based study 10: relapses and long-term disability

(2010) Antonio Scalfari et al.   BRAIN

Disease progression in multiple sclerosis: combining physicians’ and patients’ perspectives?

(2010) JJ Kragt et al.   Multiple Sclerosis Journal

Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial

(2009) Kathleen Hawker et al.   ANNALS OF NEUROLOGY

Assessing disability progression with the Multiple Sclerosis Functional Composite

(2009) RA Rudick et al.   Multiple Sclerosis Journal

Responsiveness and predictive value of EDSS and MSFC in primary progressive MS

(2008) J. J. Kragt et al.   NEUROLOGY